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EXO1

Product Name
EXO1
CAS No.
75541-83-2
Chemical Name
EXO1
Synonyms
EXO1;EOX 1;NSC 214045;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-Fluoro-benzoylami;Exo 1 >=98% (HPLC), solid;Exo1 - CAS 75541-83-2 - Calbiochem;Exo1,inhibit,Exo-1,Exo 1,Inhibitor;Methyl 2-(4-fluorobenzamido)benzoate
CBNumber
CB0713355
Molecular Formula
C15H12FNO3
Formula Weight
273.26
MOL File
75541-83-2.mol
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EXO1 Property

storage temp. 
+2C to +8C
solubility 
DMSO: 19 mg/mL, soluble
form 
solid
color 
White to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E8280
Product name
Exo 1
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$69.3
Updated
2024/03/01
Sigma-Aldrich
Product number
341220
Product name
Exo1
Packaging
25mg
Price
$182
Updated
2024/03/01
Cayman Chemical
Product number
18455
Product name
Exo 1
Purity
≥99%
Packaging
10mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
18455
Product name
Exo 1
Purity
≥99%
Packaging
50mg
Price
$324
Updated
2024/03/01
Sigma-Aldrich
Product number
E8280
Product name
Exo 1
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$244
Updated
2024/03/01
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EXO1 Chemical Properties,Usage,Production

Uses

Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 μM). It interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum by dissociating the GTPase activator ADP-ribosylation factor (ARF1) from Golgi membranes, which leads to a consequent collapse of the Golgi apparatus.

Uses

Exo 1 acts as a cell-permeable reverse inhibitor of exocytosis. Potential anti-inflammatory activity.

Uses

Exo 1 has been used as a component of the BRB80 buffer to study coat protein 1 (COPI)-mediated membrane trafficking. It has also been used as a Golgi inhibitor to study its effects on the long?interspersed?nuclear?element-1 (L1) retrotransposition.

Definition

ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides.

Biochem/physiol Actions

Exo 1 is a cell-permeable methylanthranilate analog that promotes the release of adenosine diphosphate (ADP)-ribosylation factor (ARF) 1 from Golgi membranes. It also inhibits the membrane trafficking between the endoplasmic reticulum (ER) and the Golgi bodies.

EXO1 Preparation Products And Raw materials

Raw materials

Preparation Products

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EXO1 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8012
Advantage
62
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9952
Advantage
58
Yantai ShengKailun Chemical Technology Co., Ltd.
Tel
13356901049
Fax
QQ:1025383091
Email
3119594100@qq.com
Country
China
ProdList
7964
Advantage
55
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58

75541-83-2, EXO1Related Search:


  • 4-FLUORO-BZ-2-ABZ-OME
  • 2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER
  • 2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
  • 2-(4-Fluoro-benzoylami
  • 2-(4-Fluorobenzoylamino)benzoic acid methyl ester, 2-(4-Fluorobenzoylamino)methylbenzoate
  • EOX 1
  • EXOCYTIC INHIBITOR 1
  • EXO1
  • Exo1, Exocytic Inhibitor 1, 2-(4-Fluoro-benzoylaMino)-benzoic acid Methyl ester
  • EXOCYTIC INHIBITOR 1;NSC 214045;EXO 1;EXO-1
  • NSC 214045
  • Exo1 - CAS 75541-83-2 - Calbiochem
  • Benzoic acid, 2-[(4-fluorobenzoyl)amino]-, methyl ester
  • Exo 1 >=98% (HPLC), solid
  • Exo1,inhibit,Exo-1,Exo 1,Inhibitor
  • Methyl 2-(4-fluorobenzamido)benzoate
  • 75541-83-2
  • C15H12NFO3