ChemicalBook > CAS DataBase List > (+)-ALPHA-DIHYDROTETRABENAZINE

(+)-ALPHA-DIHYDROTETRABENAZINE

Product Name
(+)-ALPHA-DIHYDROTETRABENAZINE
CAS No.
3466-75-9
Chemical Name
(+)-ALPHA-DIHYDROTETRABENAZINE
Synonyms
DTBZ;DIHYDROTETRABENAZINE;Hydroxy Tetrabenazine;(+)-ALPHA-DIHYDROTETRABEZINE;(+)-ALPHA-DIHYDROTETRABENAZINE;(+)-ALPHA-DIHYDROTETRABENAZINE;Hydroxy Tetrabenazine - Mixture of cis and trans Isomers;2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-;2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-;9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
CBNumber
CB0716932
Molecular Formula
C19H29NO3
Formula Weight
319.44
MOL File
3466-75-9.mol
More
Less

(+)-ALPHA-DIHYDROTETRABENAZINE Property

Boiling point:
457.8±45.0 °C(Predicted)
Density 
1.13±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Chloroform: soluble; Methanol: soluble
form 
A solid
pka
14.75±0.40(Predicted)
CAS DataBase Reference
3466-75-9
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
27182
Product name
Dihydrotetrabenazine
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
27182
Product name
Dihydrotetrabenazine
Packaging
1mg
Price
$230
Updated
2024/03/01
TRC
Product number
H627630
Product name
HydroxyTetrabenazine-MixtureofcisandtransIsomers
Packaging
100mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
Z3455
Product name
trans-Dihydrotetrabenazine
Packaging
1mg
Price
$353
Updated
2021/12/16
Chemtos
Product number
T-6836
Product name
2-alpha-DihydrotetrabenazineLabeledd7
Packaging
10mg
Price
$2375
Updated
2021/12/16
More
Less

(+)-ALPHA-DIHYDROTETRABENAZINE Chemical Properties,Usage,Production

Description

Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum (Kds = 2.72, 2.28, and 2.4 nM, respectively) and inhibits synaptic vesicular serotonin (5-HT) uptake (IC50s = 2.2, 2.8, and 2.3 nM, respectively). It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta (Kds = 2.9, 2.5, and 2.8 nM, respectively). Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum.

Chemical Properties

Colourless solid

Definition

ChEBI: B-Dihydrotetrabenazine is a member of isoquinolines.

(+)-ALPHA-DIHYDROTETRABENAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(+)-ALPHA-DIHYDROTETRABENAZINE Suppliers

China 17 Germany 1 India 3 Ukraine 1 United States 3 Global 25
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6854
Advantage
65
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
Advantage
56
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9507
Advantage
60
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
Shanghai Yanze Chemical Co., Ltd.
Tel
021-13773155751 19901447308
Email
260924549@qq.com
Country
China
ProdList
8709
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31163
Advantage
58

3466-75-9, (+)-ALPHA-DIHYDROTETRABENAZINERelated Search:

Butylphthalide HOMOCALYCOTOMINE (+)-9-O-DESMETHYL-ALPHA-DIHYDROTETRABENAZINE (+)-ALPHA-DIHYDROTETRABENAZINE

  • (+)-ALPHA-DIHYDROTETRABENAZINE
  • 2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-
  • DIHYDROTETRABENAZINE
  • DTBZ
  • 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-
  • 1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol
  • Hydroxy Tetrabenazine
  • (+)-ALPHA-DIHYDROTETRABEZINE
  • 9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
  • Hydroxy Tetrabenazine - Mixture of cis and trans Isomers
  • (+)-ALPHA-DIHYDROTETRABENAZINE
  • 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-
  • 3466-75-9