(+)-ALPHA-DIHYDROTETRABENAZINE
- Product Name
- (+)-ALPHA-DIHYDROTETRABENAZINE
- CAS No.
- 3466-75-9
- Chemical Name
- (+)-ALPHA-DIHYDROTETRABENAZINE
- Synonyms
- DTBZ;DIHYDROTETRABENAZINE;Hydroxy Tetrabenazine;(+)-ALPHA-DIHYDROTETRABEZINE;(+)-ALPHA-DIHYDROTETRABENAZINE;(+)-ALPHA-DIHYDROTETRABENAZINE;Hydroxy Tetrabenazine - Mixture of cis and trans Isomers;2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-;2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-;9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
- CBNumber
- CB0716932
- Molecular Formula
- C19H29NO3
- Formula Weight
- 319.44
- MOL File
- 3466-75-9.mol
(+)-ALPHA-DIHYDROTETRABENAZINE Property
- Boiling point:
- 457.8±45.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Chloroform: soluble; Methanol: soluble
- form
- A solid
- pka
- 14.75±0.40(Predicted)
- CAS DataBase Reference
- 3466-75-9
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 27182
- Product name
- Dihydrotetrabenazine
- Packaging
- 500μg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 27182
- Product name
- Dihydrotetrabenazine
- Packaging
- 1mg
- Price
- $230
- Updated
- 2024/03/01
- Product number
- H627630
- Product name
- HydroxyTetrabenazine-MixtureofcisandtransIsomers
- Packaging
- 100mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- Z3455
- Product name
- trans-Dihydrotetrabenazine
- Packaging
- 1mg
- Price
- $353
- Updated
- 2021/12/16
- Product number
- T-6836
- Product name
- 2-alpha-DihydrotetrabenazineLabeledd7
- Packaging
- 10mg
- Price
- $2375
- Updated
- 2021/12/16
(+)-ALPHA-DIHYDROTETRABENAZINE Chemical Properties,Usage,Production
Description
Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum (Kds = 2.72, 2.28, and 2.4 nM, respectively) and inhibits synaptic vesicular serotonin (5-HT) uptake (IC50s = 2.2, 2.8, and 2.3 nM, respectively). It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta (Kds = 2.9, 2.5, and 2.8 nM, respectively). Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum.
Chemical Properties
Colourless solid
Definition
ChEBI: B-Dihydrotetrabenazine is a member of isoquinolines.
(+)-ALPHA-DIHYDROTETRABENAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
(+)-ALPHA-DIHYDROTETRABENAZINE Suppliers
- Tel
- --
- Fax
- --
- info@abx.de
- Country
- Germany
- ProdList
- 369
- Advantage
- 68