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(+)-ALPHA-DIHYDROTETRABENAZINE

Product Name
(+)-ALPHA-DIHYDROTETRABENAZINE
CAS No.
3466-75-9
Chemical Name
(+)-ALPHA-DIHYDROTETRABENAZINE
Synonyms
DTBZ;DIHYDROTETRABENAZINE;Hydroxy Tetrabenazine;(+)-ALPHA-DIHYDROTETRABEZINE;(+)-ALPHA-DIHYDROTETRABENAZINE;(+)-ALPHA-DIHYDROTETRABENAZINE;Hydroxy Tetrabenazine - Mixture of cis and trans Isomers;2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-;2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-;9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
CBNumber
CB0716932
Molecular Formula
C19H29NO3
Formula Weight
319.44
MOL File
3466-75-9.mol
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(+)-ALPHA-DIHYDROTETRABENAZINE Property

Boiling point:
457.8±45.0 °C(Predicted)
Density 
1.13±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Chloroform: soluble; Methanol: soluble
form 
A solid
pka
14.75±0.40(Predicted)
CAS DataBase Reference
3466-75-9
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27182
Product name
Dihydrotetrabenazine
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
27182
Product name
Dihydrotetrabenazine
Packaging
1mg
Price
$230
Updated
2024/03/01
TRC
Product number
H627630
Product name
HydroxyTetrabenazine-MixtureofcisandtransIsomers
Packaging
100mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
Z3455
Product name
trans-Dihydrotetrabenazine
Packaging
1mg
Price
$353
Updated
2021/12/16
Chemtos
Product number
T-6836
Product name
2-alpha-DihydrotetrabenazineLabeledd7
Packaging
10mg
Price
$2375
Updated
2021/12/16
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(+)-ALPHA-DIHYDROTETRABENAZINE Chemical Properties,Usage,Production

Description

Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum (Kds = 2.72, 2.28, and 2.4 nM, respectively) and inhibits synaptic vesicular serotonin (5-HT) uptake (IC50s = 2.2, 2.8, and 2.3 nM, respectively). It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta (Kds = 2.9, 2.5, and 2.8 nM, respectively). Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum.

Chemical Properties

Colourless solid

Definition

ChEBI: B-Dihydrotetrabenazine is a member of isoquinolines.

(+)-ALPHA-DIHYDROTETRABENAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-ALPHA-DIHYDROTETRABENAZINE Suppliers

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Shaanxi Dideu Medichem Co. Ltd
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Qi Qi hang Biotechnology Co., Ltd.
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Shanghai Jieshikai Biotechnology Co. , Ltd.
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Henan Fengda Chemical Co., Ltd
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LEAPCHEM CO., LTD.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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View Lastest Price from (+)-ALPHA-DIHYDROTETRABENAZINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
(+)-ALPHA-DIHYDROTETRABENAZINE 3466-75-9
Price
US $0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-01

3466-75-9, (+)-ALPHA-DIHYDROTETRABENAZINERelated Search:


  • (+)-ALPHA-DIHYDROTETRABENAZINE
  • 2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-
  • DIHYDROTETRABENAZINE
  • DTBZ
  • 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-
  • 1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol
  • Hydroxy Tetrabenazine
  • (+)-ALPHA-DIHYDROTETRABEZINE
  • 9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
  • Hydroxy Tetrabenazine - Mixture of cis and trans Isomers
  • (+)-ALPHA-DIHYDROTETRABENAZINE
  • 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-
  • 9,10-dimethoxy-3-(propan-2-yl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol
  • 3466-75-9