3-CHLORO-2,6-DIFLUOROBENZONITRILE

Product Name: 3-CHLORO-2,6-DIFLUOROBENZONITRILE
CAS No.: 86225-73-2
Chemical Name: 3-CHLORO-2,6-DIFLUOROBENZONITRILE
Synonyms: 3-CHLORO-2,6-DIFLUOROBENZONITRILE;Benzonitrile, 3-chloro-2,6-difluoro-
CBNumber: CB0717863
Molecular Formula: C7H2ClF2N
Formula Weight: 173.55
MOL File: 86225-73-2.mol

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3-CHLORO-2,6-DIFLUOROBENZONITRILE Property

refractive index: 1.5125
storage temp.: Sealed in dry,Room Temperature
Appearance: Colorless to light yellow Liquid
Water Solubility: Not miscible or difficult to mix with water.
CAS DataBase Reference: 86225-73-2

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Safety

HazardClass: 6.1
HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: C377668
Product name: 3-Chloro-2,6-difluorobenzonitrile
Packaging: 1g
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: PC302088
Product name: 3-Chloro-2,6-difluorobenzonitrile
Purity: 98%
Packaging: 1g
Price: $37
Updated: 2021/12/16

Apolloscientific

Product number: PC302088
Product name: 3-Chloro-2,6-difluorobenzonitrile
Purity: 98%
Packaging: 5g
Price: $109
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3637-7-16
Product name: 3-Chloro-2,6-difluorobenzonitrile
Packaging: 5G
Price: $128
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3637-7-16
Product name: 3-Chloro-2,6-difluorobenzonitrile
Packaging: 25g
Price: $495
Updated: 2021/12/16

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3-CHLORO-2,6-DIFLUOROBENZONITRILE Chemical Properties,Usage,Production

Uses

3-Chloro-2,6-difluorobenzonitrile is used as a pharmaceutical intermediate.

Synthesis

4681-11-2

86225-73-2

(2) Fluorination step: In 800 g of dimethyl sulfoxide (DMSO), 206.5 g of 2,3,6-trichlorobenzonitrile was dissolved, followed by the addition of 145.3 g of potassium fluoride (KF) to the solution. The reaction mixture was heated to 170 °C with continuous stirring and maintained for 1.5 hours. After completion of the reaction, the mixture was poured into water and extracted with dichloromethane (DCM). After removing the solvent by distillation, the reaction mixture was further distilled and the fraction with a boiling point of 95 °C/11 mmHg was collected to give 166.6 g of 3-chloro-2,6-difluorobenzonitrile in 96.0% yield.

References

[1] Patent: US4406841, 1983, A
[2] Patent: US4406841, 1983, A

3-CHLORO-2,6-DIFLUOROBENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-2,6-DIFLUOROBENZONITRILE Suppliers

China 74 Germany 2 India 1 United Kingdom 5 United States 19 Global 101

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
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Energy Chemical

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Wuhan ariel chemical Co., LTD.

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Bide Pharmatech Ltd.

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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Changzhou Anxuan Chemical, Co., Ltd.

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Zhengzhou Alfachem Co., Ltd.

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View Lastest Price from 3-CHLORO-2,6-DIFLUOROBENZONITRILE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3-CHLORO-2,6-DIFLUOROBENZONITRILE 86225-73-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-10

Career Henan Chemical Co

Product: 3-CHLORO-2,6-DIFLUOROBENZONITRILE 86225-73-2
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-09

86225-73-2, 3-CHLORO-2,6-DIFLUOROBENZONITRILERelated Search:

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3-CHLORO-2,6-DIFLUOROBENZONITRILE

Benzonitrile, 3-chloro-2,6-difluoro-

86225-73-2