ChemicalBook > CAS DataBase List > 3-CHLORO-2,6-DIFLUOROBENZONITRILE

3-CHLORO-2,6-DIFLUOROBENZONITRILE

Product Name
3-CHLORO-2,6-DIFLUOROBENZONITRILE
CAS No.
86225-73-2
Chemical Name
3-CHLORO-2,6-DIFLUOROBENZONITRILE
Synonyms
3-CHLORO-2,6-DIFLUOROBENZONITRILE;Benzonitrile, 3-chloro-2,6-difluoro-
CBNumber
CB0717863
Molecular Formula
C7H2ClF2N
Formula Weight
173.55
MOL File
86225-73-2.mol
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3-CHLORO-2,6-DIFLUOROBENZONITRILE Property

refractive index 
1.5125
storage temp. 
Sealed in dry,Room Temperature
Appearance
Colorless to light yellow Liquid
Water Solubility 
Not miscible or difficult to mix with water.
CAS DataBase Reference
86225-73-2
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Safety

HazardClass 
6.1
HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
C377668
Product name
3-Chloro-2,6-difluorobenzonitrile
Packaging
1g
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
PC302088
Product name
3-Chloro-2,6-difluorobenzonitrile
Purity
98%
Packaging
5g
Price
$109
Updated
2021/12/16
SynQuest Laboratories
Product number
3637-7-16
Product name
3-Chloro-2,6-difluorobenzonitrile
Packaging
5G
Price
$128
Updated
2021/12/16
SynQuest Laboratories
Product number
3637-7-16
Product name
3-Chloro-2,6-difluorobenzonitrile
Packaging
25g
Price
$495
Updated
2021/12/16
AK Scientific
Product number
3475AC
Product name
3-Chloro-2,6-difluorobenzonitrile
Packaging
25g
Price
$521
Updated
2021/12/16
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3-CHLORO-2,6-DIFLUOROBENZONITRILE Chemical Properties,Usage,Production

Uses

3-Chloro-2,6-difluorobenzonitrile is used as a pharmaceutical intermediate.

Synthesis

4681-11-2

86225-73-2

(2) Fluorination step: In 800 g of dimethyl sulfoxide (DMSO), 206.5 g of 2,3,6-trichlorobenzonitrile was dissolved, followed by the addition of 145.3 g of potassium fluoride (KF) to the solution. The reaction mixture was heated to 170 °C with continuous stirring and maintained for 1.5 hours. After completion of the reaction, the mixture was poured into water and extracted with dichloromethane (DCM). After removing the solvent by distillation, the reaction mixture was further distilled and the fraction with a boiling point of 95 °C/11 mmHg was collected to give 166.6 g of 3-chloro-2,6-difluorobenzonitrile in 96.0% yield.

References

[1] Patent: US4406841, 1983, A
[2] Patent: US4406841, 1983, A

3-CHLORO-2,6-DIFLUOROBENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-2,6-DIFLUOROBENZONITRILE Suppliers

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View Lastest Price from 3-CHLORO-2,6-DIFLUOROBENZONITRILE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
3-CHLORO-2,6-DIFLUOROBENZONITRILE 86225-73-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-10
Career Henan Chemical Co
Product
3-CHLORO-2,6-DIFLUOROBENZONITRILE 86225-73-2
Price
US $3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-09

86225-73-2, 3-CHLORO-2,6-DIFLUOROBENZONITRILERelated Search:

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  • 3-CHLORO-2,6-DIFLUOROBENZONITRILE
  • Benzonitrile, 3-chloro-2,6-difluoro-
  • 86225-73-2