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A 61603 HYDROBROMIDE

Product Name
A 61603 HYDROBROMIDE
CAS No.
107756-30-9
Chemical Name
A 61603 HYDROBROMIDE
Synonyms
A 61603;A 61603 HYDROBROMIDE;N-[5-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-2-HYDROXY-5,6,7,8-TETRAHYDRONAPHTHALEN-1-YL]METHANESULFONAMIDE HYDROBROMIDE;N-(5-(4,5-Dihydro-(1H)-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)methanesulfonamidehydrobromide
CBNumber
CB0723691
Molecular Formula
C14H20BrN3O3S
Formula Weight
390.3
MOL File
107756-30-9.mol
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A 61603 HYDROBROMIDE Property

storage temp. 
Desiccate at +4°C
solubility 
Soluble in H2O
form 
crystalline solid
color 
White to off-white
Water Solubility 
Soluble to 50 mM in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17358
Product name
A-61603
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17358
Product name
A-61603
Purity
≥98%
Packaging
5mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
17358
Product name
A-61603
Purity
≥98%
Packaging
10mg
Price
$139
Updated
2024/03/01
Tocris
Product number
1052
Product name
A61603hydrobromide
Packaging
10
Price
$195
Updated
2021/12/16
Tocris
Product number
1052
Product name
A61603hydrobromide
Packaging
50
Price
$818
Updated
2021/12/16
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A 61603 HYDROBROMIDE Chemical Properties,Usage,Production

Uses

A 61603 is a selective α1A-adrenergic receptor agonist.

Biological Activity

Potent α -adrenoceptor agonist that is at least 35-fold more potent at α 1A than at α 1B or α 1D sites. Induces dose response increases in spontaneous Ca 2+ transients in rat ventricular myocytes in vitro (EC 50 = 6.9 nmol/L). Also available as part of the α 1 -Adrenoceptor Tocriset™ .

storage

Desiccate at +4°C

References

[1]. knepper sm, buckner sa, brune me, et al. a-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1a receptor subtype. j pharmacol exp ther, 1995, 274(1): 97-103.
[2]. meyer md, altenbach rj, hancock aa, et al. synthesis and in vitro characterization of n-[5-(4,5-dihydro-1h-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: a novel selective alpha 1a receptor agonist. j med chem, 1996, 39(20): 4116-4119.
[3]. luo dl, gao j, fan ll, et al. receptor subtype involved in alpha 1-adrenergic receptor-mediated ca2+ signaling in cardiomyocytes. acta pharmacol sin, 2007, 28(7): 968-974.
[4]. martínez-salas sg1, campos-peralta jm, pares-hipolito j, et al. alpha1a-adrenoceptors predominate in the control of blood pressure in mouse mesenteric vascular bed. auton autacoid pharmacol, 2007, 27(3): 137-142.

A 61603 HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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A 61603 HYDROBROMIDE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32038
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30241
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
Jinan Jiuli Biotechnology Co. , Ltd.
Tel
15865264761
Email
486064515@qq.com
Country
China
ProdList
3542
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24649
Advantage
58
Shanghai Tachizaki Biomedical Research Center
Tel
18014399201
Email
sales@chemlab-tachizaki.com
Country
China
ProdList
2559
Advantage
58

107756-30-9, A 61603 HYDROBROMIDERelated Search:


  • N-[5-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-2-HYDROXY-5,6,7,8-TETRAHYDRONAPHTHALEN-1-YL]METHANESULFONAMIDE HYDROBROMIDE
  • N-(5-(4,5-Dihydro-(1H)-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)methanesulfonamidehydrobromide
  • A 61603 HYDROBROMIDE
  • A 61603
  • 107756-30-9
  • C14H20BRN3O3S
  • C14H19N3O3SHBr