ChemicalBook > CAS DataBase List > p-Tolyl isocyanate

p-Tolyl isocyanate

Product Name
p-Tolyl isocyanate
CAS No.
622-58-2
Chemical Name
p-Tolyl isocyanate
Synonyms
1-Isocyanato-4-methylbenzene;4-METHYLPHENYL ISOCYANATE;1-isocyanato-4-methyl-Benzene;P-TOLYISOCYANATE;p-Tolylcarbonimide;P-TOLYL ISOCYANATE;4-TOLYL ISOCYANATE;p-Isocyanatotoluene;p-tolueneisocyanate;4-Isocyanatotoluene
CBNumber
CB0731054
Molecular Formula
C8H7NO
Formula Weight
133.15
MOL File
622-58-2.mol
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p-Tolyl isocyanate Property

Melting point:
155-156 °C(Solv: acetonitrile (75-05-8); hexane (110-54-3))
Boiling point:
70-72 °C/10 mmHg (lit.)
Density 
1.056 g/mL at 25 °C (lit.)
vapor pressure 
75.5Pa at 25℃
refractive index 
n20/D 1.531(lit.)
Flash point:
152 °F
storage temp. 
2-8°C
form 
Liquid
color 
Clear slightly brown
Water Solubility 
7.5g/L at 20℃
Sensitive 
Moisture Sensitive
BRN 
471494
InChIKey
MGYGFNQQGAQEON-UHFFFAOYSA-N
LogP
1.39
CAS DataBase Reference
622-58-2(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-isocyanato-4-methyl-(622-58-2)
EPA Substance Registry System
p-Tolyl isocyanate (622-58-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-42
Safety Statements 
23-26-45-36/37/39
RIDADR 
2206
WGK Germany 
3
RTECS 
DA3681666
F 
21
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29299010
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
143634
Product name
p-Tolyl isocyanate
Purity
99%
Packaging
5g
Price
$48.4
Updated
2025/07/31
Sigma-Aldrich
Product number
143634
Product name
p-Tolyl isocyanate
Purity
99%
Packaging
25g
Price
$72.2
Updated
2025/07/31
TCI Chemical
Product number
T0321
Product name
p-Tolyl Isocyanate
Purity
>98.0%(GC)
Packaging
25g
Price
$86
Updated
2025/07/31
TCI Chemical
Product number
T0321
Product name
p-Tolyl Isocyanate
Purity
>98.0%(GC)
Packaging
100g
Price
$210
Updated
2025/07/31
Sigma-Aldrich
Product number
143634
Product name
p-Tolyl isocyanate
Purity
99%
Packaging
100g
Price
$245
Updated
2025/07/31
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p-Tolyl isocyanate Chemical Properties,Usage,Production

Chemical Properties

CLEAR SLIGHTLY BROWN LIQUID

Uses

p-Tolyl isocyanate was used to study the catalytic role of supported Rhodium(I) complex toward the reductive carbonylation of nitrobenzene in DMF medium.

Definition

ChEBI: An isocyanate comprising a benzene core with isocyanato and methyl substituents para to each other.

General Description

p-Tolyl isocyanate reacts with human serum albumin to form antigen which helps in detecting IgE antibodies in workers hypersensitive to toluene diisocyanate.

Hazard

A Poison by inhalation. Moderately toxic by ingestion.

p-Tolyl isocyanate Preparation Products And Raw materials

Raw materials

Preparation Products

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p-Tolyl isocyanate Suppliers

Belgium 2 China 181 China Hong Kong 1 Czech Republic 1 Germany 4 India 9 Japan 2 Poland 1 South Korea 2 Spain 1 Switzerland 2 Ukraine 1 United Kingdom 9 United States 25 Global 241
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View Lastest Price from p-Tolyl isocyanate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
p-Tolyl isocyanate 622-58-2
Price
US $1000.00/KG
Min. Order
0.1KG
Purity
98%HPLC
Supply Ability
2tons
Release date
2025-08-15
Hebei Chuanghai Biotechnology Co., Ltd
Product
p-Tolyl isocyanate 622-58-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
p-Tolyl isocyanate 622-58-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

622-58-2, p-Tolyl isocyanateRelated Search:

Isocyanatocyclohexane Chlorosulfonyl isocyanate 1,4-PHENYLENE DIISOTHIOCYANATE Phenyl isothiocyanate Propyl isocyanate Sodium p-toluenesulfinate p-Toluenesulfonyl Isocyanate ISOCYANATE 4-Chloro-α,α,α-trifluoro-m-tolyl isocyanate 4-TOLYL ISOCYANATE 4-Chloro-2-isocyanatotoluene 4-Methoxy-o-tolyl isocyanate à,à,à-trifluoro-p-tolyl isocyanate,ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLYL ISOCYANATE,α,α,α-Trifluoro-p-tolyl isocyanate 6-Methoxy-m-tolyl isocyanate O-TOLYL ISOCYANATE, 99+%,O-TOLYL ISOCYANATE,2-TOLYL ISOCYANATE 2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 3-chloro-p-tolyl isocyanate TOLUALDEHYDES

  • Isocyanic acid, p-tolyl ester (7CI,8CI)
  • Oftoluene diisocyanate
  • p-Tolyl isocyanate 99%
  • benzene,1-isocyanato-4-methyl-
  • isocyanatedep-toluene
  • p-Isocyanatotoluene
  • p-Toluene isocyanate
  • p-tolueneisocyanate
  • AROCLOR 1232, 1X1ML, HEXANE 1000UG/ML
  • p-Tolylisocyanate,99%
  • PARA-TOLYL(MONO)ISOCYANATE
  • P-TOLYISOCYANATE
  • p-Tolylcarbonimide
  • para-tolyl isocyanate
  • p-Tolyl isocyanate, 99% 25GR
  • ISOCYANIC ACID P-TOLYL ESTER
  • P-METHYL PHENYL ISOCYANATE
  • P-TOLYL ISOCYANATE
  • 1-isocyanato-4-methyl-benzen
  • 1-Isocyanato-4-methylbenzene
  • 1-isocyanato-4-methyl-Benzene
  • 4-Isocyanato-1-methylbenzene
  • 4-Isocyanatotoluene
  • 4-METHYLPHENYL ISOCYANATE
  • 4-TOLYL ISOCYANATE
  • <i>p</i>-Tolyl isocyanate
  • 622-58-2
  • Isocyanates
  • Nitrogen Compounds
  • Organic Building Blocks
  • Building Blocks
  • ester series
  • organic chemical