BENZATHINE PENICILLINE G TETRAHYDRATE Property

Melting point:

>118°C (dec.)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly)

color 

White to Off-White

Safety

Hazard Codes 

Xi

Risk Statements 

42/43

Safety Statements 

22-36/37-45-24/25

HS Code 

29411099

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H332Harmful if inhaled

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

BENZATHINE PENICILLINE G TETRAHYDRATE Chemical Properties,Usage,Production

Uses

Antibacterial.

Uses

Penicillin G Benzathine is an antimicrobial medicament. Used in the treatment of pneumococcus and streptococcus bacterial infections.

brand name

Bicillin (Wyeth); Permapen (Pfizer).

Clinical Use

Benzylpenicillin benzathine was developed as a dilatorily acting benzylpenicillin that maintains an effective serum concentration for 2 days following a single intramuscular injection of 600000 U. It is also used as an orally active benzylpenicillin because it is only slightly affected by a patient’s meal .