ChemicalBook > CAS DataBase List > L-Canavanine sulfate

L-Canavanine sulfate

Product Name
L-Canavanine sulfate
CAS No.
2219-31-0
Chemical Name
L-Canavanine sulfate
Synonyms
L-CANAVANINE SULPHATE;CANAVANINE SULFATE;canavanine sulphate;L-CANAVANINE SULFATE;CANAVANINE SULFATE, L-;CANAVANINE SULFATE, L-(P);L-Canavanine Sulfate L-CANAVANINE SULFATE SALT;CANAVANINE SULFATE, L-(RG);L-CANAVANINE SULFATE HYDRATE
CBNumber
CB0746906
Molecular Formula
C5H14N4O7S
Formula Weight
274.25
MOL File
2219-31-0.mol
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L-Canavanine sulfate Property

Melting point:
160-165 °C (dec.)
storage temp. 
2-8°C
solubility 
H2O: 100 mg/mL
form 
powder
color 
white
BRN 
6121291
Stability:
Hygroscopic
CAS DataBase Reference
2219-31-0(CAS DataBase Reference)
EPA Substance Registry System
L-Canavanine sulfate (2219-31-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
36-26
RIDADR 
2811
WGK Germany 
3
HS Code 
2925290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C9758
Product name
L-Canavanine sulfate salt
Purity
≥99% (TLC), powder
Packaging
1g
Price
$242
Updated
2024/03/01
Sigma-Aldrich
Product number
C9758
Product name
L-Canavanine sulfate salt
Purity
≥99% (TLC), powder
Packaging
5g
Price
$919
Updated
2024/03/01
TCI Chemical
Product number
C0018
Product name
L-Canavanine Sulfate Hydrate
Purity
>97.0%(T)
Packaging
100mg
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
C9758
Product name
L-Canavanine sulfate salt
Purity
≥99% (TLC), powder
Packaging
100mg
Price
$56.1
Updated
2024/03/01
Sigma-Aldrich
Product number
C9758
Product name
L-Canavanine sulfate salt
Purity
≥99% (TLC), powder
Packaging
250mg
Price
$71.4
Updated
2024/03/01
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L-Canavanine sulfate Chemical Properties,Usage,Production

Uses

A Nitric Oxide Synthase inhibitor

Uses

Canavanine sulfate salt has been used:

  • as a translation inhibitor in yeast translation studies
  • as a component of synthetic complete (SC) drop-out medium for screening yeast
  • for screening Saccharomyces cerevisiae in canavanine mutation frequency assay

Definition

ChEBI: An organic sulfate salt obtained by combining L-canavanine with one molar equivalent of sulfuric acid.

General Description

Canavanine is a homolog of arginine and a non-protein amino acid. It is present in plants like alfalfa, cloves, beans onions and sprouts. Canavanine is synthesized from L-canavaninosuccinic acid and the biosynthetic pathway was first elucidated in jack bean plant.

Biological Activity

NO synthase inhibitor.

Biochem/physiol Actions

Canavanine is a naturally occurring?L-amino acid that competes and interferes with?L-arginine-utilizing enzymes due to its structural similarity with this?L-amino acid. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). It acts as a substrate for arginyl tRNA and is incorporated during protein synthesis leading to aberrant canavanyl proteins. Supplementation with canavanine worsens the alfalfa induced Systemic lupus erythematosus (SLE) like syndrome and its incorporation with endosome and proteasome disrupts the antigen processing.

Purification Methods

Recrystallise the sulfate by dissolving (~1g) in H2O (10mL), and adding with stirring 0.5 to 1.0 volumes of 95% EtOH whereby crystals separate. These are collected, washed with Me2CO/EtOH (1:1) and dried over P2O5 in a vacuum. [Hunt & Thompson Biochemical Preparations 13 416 1971, Feacon & Bell Biochem J 59 221 1955, Beilstein 4 III 1636, 4 IV 3188.]

L-Canavanine sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Canavanine sulfate Suppliers

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View Lastest Price from L-Canavanine sulfate manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
L-CANAVANINE SULFATE 2219-31-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
L-CANAVANINE SULFATE 2219-31-0
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-24

2219-31-0, L-Canavanine sulfateRelated Search:

AMT HYDROCHLORIDE 1,4-PBIT DIHYDROBROMIDE L-Canavanine sulfate L-CANALINE BASE Ammonium sulfite monohydrate DL-Homoserine Ammonium sulfate Sulfuric acid Formamidine acetate L-Canavanine Ammonium Sulfite Guanidine acetate METHYLAMINE SULFATE L-HOMOSERINE HYDROCHLORIDE L-(+)-CANAVANINE SULFATE MONOHYDRATE 9&,L-(+)-Canavanine sulfate salt monohydrate,L-(+)-CANAVANINE SULFATE MONOHYDRATE, 98 % D-Canavanine sulfate DL-Canavanine sulfate L-(+)-CANAVANINE SULFATE MONOHYDRATE

  • canavanine sulphate
  • L-canavanine sulfate crystalline
  • L-Canavanine Sulfate, Canavalia ensiformis
  • l-α-amino-γ-(guanidinooxy)butyric acid sulfate salt
  • CANAVANINE SULFATE, L-(RG)
  • L-CANAVANINE SULFATE HYDRATE
  • L-CANAVANINE SULFATE
  • CANAVANINE SULFATE
  • CANAVANINE SULFATE, L-
  • o-[(aminoiminomethyl)amino]-l-homoserinsulfate(1:1)
  • L-Canavanine sulfate L-Canavanine sulfate
  • 2-AMino-4-(guanidinooxy)butyric Acid Sulfate
  • O-[(AMinoiMinoMethyl)aMino]-L-hoMoserine Sulfate
  • CANAVANINE SULFATE, L-(P)
  • L-HoMoserine, O-[(aMinoiMinoMethyl)aMino]-, sulfate (1:1)
  • O-{[amino(imino)methyl]amino}homoserine sulfate (salt)
  • L-Canavanine Sulfate&nbsp
  • L-2-AMINO-4-(GUANIDIOOXY)BUTYRIC ACID SULFATE
  • L-ALPHA-AMINO-GAMMA-(GUANIDINOOXYL)-N-BUTYRIC ACID SULFATE
  • L-ALPHA-AMINO-GAMMA (GUANIDINOOXY)-N-BUTYRIC ACID SULFATE
  • L-ALPHA-AMINO-GAMMA-[GUANIDINOOXY]-N-BUTYRIC ACID SULFATE SALT
  • L-CANAVANINE SULFATE SALT
  • L-CANAVANINE SULPHATE
  • (S)-2-Amino-4-(guanidinooxy)butanoic acid compound with sulfuric acid (1:1)
  • L-Canavanine Sulfate Hydrate&gt
  • L-Canavanine sulfate USP/EP/BP
  • 2219-31-0
  • C5H14N4O7S
  • C5H12O3N3
  • C5H12N4OH2SO4
  • C5H12N4O3H2SO4
  • C5H12N4O3xH2SO4
  • C5H12N4O3H2SO4xH2O
  • C5H12N4O3H2O4S
  • Biochemicals and Reagents
  • BioChemical
  • L to O
  • Peptide Synthesis
  • Others
  • Nitric Oxide Synthase (iNOS)
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Enzyme
  • Enzymes, Inhibitors, and Substrates
  • Hydroxylamines (N-Substituted)
  • Hydroxylamines
  • Hydroxylamines (O-Substituted)
  • amino acid derivative
  • Amino Acids & Derivatives
  • Amino Acids
  • Inhibitors
  • Nitric Oxide Reagents
  • Hydroxylamines (N-Substituted)
  • Hydroxylamines (O-Substituted)
  • non-Proteinorganic Amino Acids
  • Amino Acids
  • Biochemistry