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PPADS TETRASODIUM SALT

Product Name
PPADS TETRASODIUM SALT
CAS No.
192575-19-2
Chemical Name
PPADS TETRASODIUM SALT
Synonyms
PPADS;PPADS Tetrasodium;4'-disulfonic acid;PPADS (sodium salt);PPADS TETRASODIUM SALT;PPADS tetrasodium salt hydrate;PPADS tetrasodium salt, anhydrous;Pyridoxalphosphate-6-azophenyl-2';pyridoxal-phosphate-6-azophenyl-2',4'- disulfoni;PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID 4NA
CBNumber
CB0758079
Molecular Formula
C14H15N3NaO12PS2
Formula Weight
535.37
MOL File
192575-19-2.mol
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PPADS TETRASODIUM SALT Property

storage temp. 
−20°C
solubility 
H2O: >10 mg/mL
form 
solid
color 
red to orange
Water Solubility 
Soluble to 100 mM in water
Stability:
Unstable in Aqueous Solution
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P178
Product name
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate
Purity
solid, ≥98% (HPLC)
Packaging
10mg
Price
$100
Updated
2024/03/01
Sigma-Aldrich
Product number
P178
Product name
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate
Purity
solid, ≥98% (HPLC)
Packaging
50mg
Price
$234.6
Updated
2024/03/01
Cayman Chemical
Product number
14537
Product name
PPADS (sodium salt)
Purity
≥95%
Packaging
10mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
14537
Product name
PPADS (sodium salt)
Purity
≥95%
Packaging
50mg
Price
$183
Updated
2024/03/01
Sigma-Aldrich
Product number
P178
Product name
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate
Purity
solid, ≥98% (HPLC)
Packaging
250mg
Price
$1610
Updated
2023/06/20
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PPADS TETRASODIUM SALT Chemical Properties,Usage,Production

Uses

P2X and P2Y purinergic receptors are ATP-sensitive receptors responsible for mediating a large variety of excitatory postsynaptic responses including fast transmission at central synapses, contraction of smooth muscle cells, platelet aggregation, macrophage activation, and apoptosis. PPADS is a non-selective P2 purinergic antagonist that blocks recombinant P2X1-5 (IC50s = 1-2.6 μM), native P2Y2-like (IC50 = ~0.9 mM), and recombinant P2Y4 (IC50 = ~15 mM) receptors. PPADS antagonism of ATP-sensitive P2 receptors produces neuroprotective effects in an ischemia model with permanent middle cerebral artery occlusion in spontaneously hypertensive rats.

Uses

PPADS Tetrasodium is an non-selective purinergic antagonists of P2 ATP receptors. PPADS Tetrasodium is also a potential neuroprotective agents for the treatment of autoimmune and demyelinating disease.

Definition

ChEBI: Tetrasodium 5'-phosphonatopyridoxal-6-azobenzene-2,4-disulfonate is an organic sodium salt that is the tetrasodium salt of 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid It has a role as a purinergic receptor P2X antagonist. It is an organic sodium salt and an organosulfonate salt. It contains a 5'-phosphonatopyridoxal-6-azobenzene-2,4-disulfonate.

storage

-20°C (desiccate)

PPADS TETRASODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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PPADS TETRASODIUM SALT Suppliers

Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74

192575-19-2, PPADS TETRASODIUM SALTRelated Search:


  • PPADS Tetrasodium
  • PPADS tetrasodium salt, anhydrous
  • PPADS (sodium salt)
  • 4-[(2E)-2-[4-formyl-6-methyl-5-oxo-3-(phosphonatooxymethyl)pyridin-2-ylidene]hydrazinyl]benzene-1,3-disulfonate
  • PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULFONIC ACID TETRASODIUM SALT
  • PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID 4NA
  • PYRIDOXAL-PHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID TETRASODIUM
  • PPADS
  • PPADS TETRASODIUM SALT
  • pyridoxal-phosphate-6-azophenyl-2',4'- disulfoni
  • PYRIDOXAL-PHOSPHATE-6-AZOPHENYL-2',4'-DI -SULPHONIC ACID TETRAS
  • PPADS hydrate tetrasodium salt, 4-[[4-Formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-2-pyridinyl]azo]-1,3-benzenedisulfonic acid tetrasodium salt
  • Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) hydrate tetrasodium salt
  • 4-[[4-FORMYL-5-HYDROXY-6-METHYL-3-[(PHOSPHONOOXY)METHYL]-2-PYRIDINYL]AZO]-1,3-BENZENEDISULFONIC ACID TETRASODIUM
  • PPADS tetrasodium salt hydrate
  • Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate
  • 4'-disulfonic acid
  • Pyridoxalphosphate-6-azophenyl-2'
  • 192575-19-2
  • C14H10N3Na4O12PS2
  • Adenosines/P2 Nucleotide Receptor - Antagonists
  • Adenosines/P2 Nucleotide Receptors (Purinergics)
  • GPCR Modulators
  • GPCR Proteins
  • Ligand-Gated Ion Channels
  • Membrane Protein Biology Tools
  • Modulators and Antibodies
  • P2X Receptor Modulators
  • Proteins and Derivatives
  • Aldehydes
  • Antagonists
  • Bioactive Small Molecules
  • Biochemicals and Reagents
  • Building Blocks
  • C13-C60
  • Carbonyl Compounds
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Chemical Synthesis
  • Ion Channels
  • Neuroscience
  • Neurotransmission
  • Neurotransmitters
  • Organic Building Blocks
  • P