ChemicalBook > CAS DataBase List > 15(S)-HPETE

15(S)-HPETE

Product Name
15(S)-HPETE
CAS No.
70981-96-3
Chemical Name
15(S)-HPETE
Synonyms
15(S)-HPETE;15(S)HpETE,15(S) HpETE;15(S)-HpETE(solution in ethanol);15(S)-HpETE Lipid Maps MS Standard;15-Hydroxyeicosa-5Z,8Z,11Z,13E-tetraenoic acid;15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-*eicosatetraeno;15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-*EICOS ATETRAENOIC;15(S)-HYDROPEROXYEICOSA-5Z,8Z,11Z,13E-TETRAENOIC ACID;15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-EICOSATETRAENOIC ACID;(S-(E,Z,Z,Z))-15-Hydroperoxy-5,8,11,13-eicosatetraenoic acid
CBNumber
CB0759041
Molecular Formula
C20H32O4
Formula Weight
336.47
MOL File
70981-96-3.mol
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15(S)-HPETE Property

Flash point:
14 °C
storage temp. 
−70°C
solubility 
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form 
Liquid
color 
Colorless to light yellow
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Safety

Hazard Codes 
F
Risk Statements 
11
Safety Statements 
7-16
RIDADR 
UN 1170 3/PG 3
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H9521
Product name
15(S)-Hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid
Purity
~100?μg/mL in ethanol, ≥95%
Packaging
50μg
Price
$457
Updated
2022/05/15
Cayman Chemical
Product number
44720
Product name
15(S)-HpETE
Purity
≥98%
Packaging
25μg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
44720
Product name
15(S)-HpETE
Purity
≥98%
Packaging
50μg
Price
$65
Updated
2024/03/01
Cayman Chemical
Product number
44720
Product name
15(S)-HpETE
Purity
≥98%
Packaging
100μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
44720
Product name
15(S)-HpETE
Purity
≥98%
Packaging
250μg
Price
$283
Updated
2024/03/01
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15(S)-HPETE Chemical Properties,Usage,Production

Uses

15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 or reduced to 15(S)-HETE by peroxidases. 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.

Uses

15(S)-HPETE is a primary metabolite of arachidonic acid shown to inhibit arachidonic acid induced platelet aggregation.

Definition

ChEBI: The (S)-enantiomer of 15-HPETE.

IC 50

c-Fos; c-Jun

15(S)-HPETE Preparation Products And Raw materials

Raw materials

Preparation Products

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15(S)-HPETE Suppliers

China 48 Germany 1 India 1 Italy 1 Japan 1 Switzerland 2 United Kingdom 2 United States 7 Global 63
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70981-96-3, 15(S)-HPETERelated Search:

15(S)-HPETE LIPID MAPS (+/-)15-HETE n-butylhydroperoxide 15(S)-HPETE [1-14C] 15(S)-HETE 15(S)-HPETE, [3H] 15(S)-HPETE

  • 15(S)-HPETE
  • 15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-*eicosatetraeno
  • 15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-*EICOS ATETRAENOIC
  • 15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-EICOSATETRAENOIC ACID (2MG/ML ETHANOL SOLUTION)
  • 15-Hydroxyeicosa-5Z,8Z,11Z,13E-tetraenoic acid
  • (S-(E,Z,Z,Z))-15-Hydroperoxy-5,8,11,13-eicosatetraenoic acid
  • 5,8,11,13-Eicosatetraenoic acid, 15-hydroperoxy-, (S-(E,Z,Z,Z))-
  • 15(S)-HpETE Lipid Maps MS Standard
  • 15(S)-Hydroperoxy-5(Z),8(Z),11(Z),13(E)-eicosatetraenoic acid [15(S)-HPETE]
  • 15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-EICOSATETRAENOIC ACID
  • 15(S)-HYDROPEROXYEICOSA-5Z,8Z,11Z,13E-TETRAENOIC ACID
  • 5,8,11,13-Eicosatetraenoic acid, 15-hydroperoxy-, (5Z,8Z,11Z,13E,15S)-
  • 15(S)-Hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid ~100 mug/mL in ethanol,
  • 15(S)HpETE,15(S) HpETE
  • 15(S)-HpETE(solution in ethanol)
  • 70981-96-3
  • Fatty Acids
  • Unsaturated fatty acids and derivatives
  • Polyunsaturated
  • Hydroperoxy fatty acids
  • Lipids
  • Biochemicals and Reagents
  • BioChemical