15(S)-HPETE
- Product Name
- 15(S)-HPETE
- CAS No.
- 70981-96-3
- Chemical Name
- 15(S)-HPETE
- Synonyms
- 15(S)-HPETE;15(S)HpETE,15(S) HpETE;15(S)-HpETE Lipid Maps MS Standard;15-Hydroxyeicosa-5Z,8Z,11Z,13E-tetraenoic acid;15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-*eicosatetraeno;15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-*EICOS ATETRAENOIC;15(S)-HYDROPEROXYEICOSA-5Z,8Z,11Z,13E-TETRAENOIC ACID;15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-EICOSATETRAENOIC ACID;(S-(E,Z,Z,Z))-15-Hydroperoxy-5,8,11,13-eicosatetraenoic acid;5,8,11,13-Eicosatetraenoic acid, 15-hydroperoxy-, (S-(E,Z,Z,Z))-
- CBNumber
- CB0759041
- Molecular Formula
- C20H32O4
- Formula Weight
- 336.47
- MOL File
- 70981-96-3.mol
15(S)-HPETE Property
- Flash point:
- 14 °C
- storage temp.
- −70°C
- solubility
- 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P235Store in a well-ventilated place. Keep cool.
N-Bromosuccinimide Price
- Product number
- H9521
- Product name
- 15(S)-Hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid
- Purity
- ~100?μg/mL in ethanol, ≥95%
- Packaging
- 50μg
- Price
- $457
- Updated
- 2022/05/15
- Product number
- 44720
- Product name
- 15(S)-HpETE
- Purity
- ≥98%
- Packaging
- 25μg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 44720
- Product name
- 15(S)-HpETE
- Purity
- ≥98%
- Packaging
- 50μg
- Price
- $65
- Updated
- 2024/03/01
- Product number
- 44720
- Product name
- 15(S)-HpETE
- Purity
- ≥98%
- Packaging
- 100μg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 44720
- Product name
- 15(S)-HpETE
- Purity
- ≥98%
- Packaging
- 250μg
- Price
- $283
- Updated
- 2024/03/01
15(S)-HPETE Chemical Properties,Usage,Production
Uses
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 or reduced to 15(S)-HETE by peroxidases. 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.
Uses
15(S)-HPETE is a primary metabolite of arachidonic acid shown to inhibit arachidonic acid induced platelet aggregation.
Definition
ChEBI: The (S)-enantiomer of 15-HPETE.