ChemicalBook > CAS DataBase List > 5-Benzyloxyindole

5-Benzyloxyindole

Product Name
5-Benzyloxyindole
CAS No.
1215-59-4
Chemical Name
5-Benzyloxyindole
Synonyms
NSC 62895;bredreck`s;5-Benzyindole;5-BENZYLOXYINDOLE;5-benzyloxy-indol;Benzyloxy-5 indole;BENZYLOXYINDOLE(5-);TIMTEC-BB SBB003331;5-BENZYLOXY-1H-INDOLE;5-Benzyloxyindole,95%
CBNumber
CB0772987
Molecular Formula
C15H13NO
Formula Weight
223.27
MOL File
1215-59-4.mol
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5-Benzyloxyindole Property

Melting point:
100-104 °C (lit.)
Boiling point:
364.56°C (rough estimate)
Density 
1.0707 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
2-8°C
solubility 
ethanol: may be hazy yellow
form 
powder
pka
16.63±0.30(Predicted)
color 
white to light yellow
BRN 
173532
Exposure limits
ACGIH: TWA 20 ppm
OSHA: Ceiling 300 ppm; TWA 200 ppm
NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3)
CAS DataBase Reference
1215-59-4(CAS DataBase Reference)
NIST Chemistry Reference
1H-indole, 5-(phenylmethoxy)-(1215-59-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-24/25-22
WGK Germany 
3
RTECS 
NL4850000
8-10
HazardClass 
IRRITANT
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H333May be harmful if inhaled

H335May cause respiratory irritation

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B27803
Product name
5-(Benzyloxy)indole
Purity
95%
Packaging
5g
Price
$33.7
Updated
2024/03/01
Sigma-Aldrich
Product number
B27803
Product name
5-(Benzyloxy)indole
Purity
95%
Packaging
25g
Price
$90.9
Updated
2024/03/01
TCI Chemical
Product number
B1833
Product name
5-Benzyloxyindole
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$114
Updated
2024/03/01
Alfa Aesar
Product number
B25143
Product name
5-Benzyloxyindole, 94%, may contain up to ca 7% toluene
Packaging
1g
Price
$36.5
Updated
2024/03/01
Alfa Aesar
Product number
B25143
Product name
5-Benzyloxyindole, 94%, may contain up to ca 7% toluene
Packaging
5g
Price
$107
Updated
2024/03/01
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5-Benzyloxyindole Chemical Properties,Usage,Production

Chemical Properties

Off-white to beige powder

Uses

Reactant in regio- and stereoselective morpholine-catalyzed direct C-3 alkenylation with α,β-unsaturated aldehydes Reactant in selective debenzylation of protective groups using SiliaCat-palladium under mild reaction conditions Reactant in metal-free Friedel-Crafts alkylation reactions Reactant in preparation of protein kinase (PKC) inhibitors Reactant in preparation of indole/quinoline carbothioic acid amide derivatives.

Uses

  • Reactant in regio- and stereoselective morpholine-catalyzed direct C-3 alkenylation with α,β-unsaturated aldehydes
  • Reactant in selective debenzylation of protective groups using SiliaCat-palladium under mild reaction conditions
  • Reactant in metal-free Friedel-Crafts alkylation reactions
  • Reactant in preparation of protein kinase (PKC) inhibitors
  • Reactant in preparation of indole/quinoline carbothioic acid amide derivatives

Uses

5-Benzyloxyindole is used as reagent/reactant in regioselective preparation of CF3-β-tryptamine derivatives via base-free thermal ring-opening reaction of N-nosyl-2-CF3-aziridine with indoles.

Purification Methods

It is recrystallised from *C6H6/pet ether or pet ether. The picrate forms red crystals from *C6H6 and has m 142-143o. [Burton & Leong Chem Ind (London) 1035 1953, Ek & Witkop J Am Chem Soc 76 5579 1954, fluorescence: Bridges & Williams Biochem J 107 225 1968, Beilstein 27 III/IV 1758.]

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View Lastest Price from 5-Benzyloxyindole manufacturers

Wuhan Circle Star Chem-medical Technology Co.,Ltd
Product
5-Benzyloxyindole 1215-59-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98
Supply Ability
1000
Release date
2025-01-21
Hebei Mojin Biotechnology Co.,Ltd
Product
5-Benzyloxyindole 1215-59-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-06-03
Henan Fengda Chemical Co., Ltd
Product
5-Benzyloxyindole 1215-59-4
Price
US $10.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-28

1215-59-4, 5-BenzyloxyindoleRelated Search:


  • BENZYLOXYINDOLE(5-)
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