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5-HYDROXYTRYPTOPHOL

Product Name
5-HYDROXYTRYPTOPHOL
CAS No.
154-02-9
Chemical Name
5-HYDROXYTRYPTOPHOL
Synonyms
NSC 84416;hydroxytryptophol;3-(2-Hydroxyethyl);5-HYDROXYTRYPTOPHOL;5-hydroxy-indole-3-ethano;5-HYDROXYINDOLE-3-ETHANOL;5-HYDROXYTRYPTOPHOL(5OHIEt);5-hydroxy-1h-indole-3-ethano;5-hydroxy-1h-indole-3-ethanol;1H-Indole-3-ethanol,5-hydroxy-
CBNumber
CB3250862
Molecular Formula
C10H11NO2
Formula Weight
177.2
MOL File
154-02-9.mol
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5-HYDROXYTRYPTOPHOL Property

Melting point:
111-113°
Boiling point:
435.2±30.0 °C(Predicted)
Density 
1.356±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
10.07±0.40(Predicted)
color 
White to Light Red
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Safety

RTECS 
NL8512500
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16114
Product name
5-hydroxy Tryptophol
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
16114
Product name
5-hydroxy Tryptophol
Purity
≥98%
Packaging
10mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
16114
Product name
5-hydroxy Tryptophol
Purity
≥98%
Packaging
25mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
16114
Product name
5-hydroxy Tryptophol
Purity
≥98%
Packaging
100mg
Price
$275
Updated
2024/03/01
TRC
Product number
H976000
Product name
5-HydroxyTryptophol
Packaging
10mg
Price
$65
Updated
2021/12/16
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5-HYDROXYTRYPTOPHOL Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Powder

Uses

A metabolite of Tryptophan (T947200).

Definition

ChEBI: 5-Hydroxytryptophol is a member of indoles.

Hazard

A reproductive hazard.

Biological Activity

5-hydroxy tryptophol is a metabolite of tryptophan.tryptophan (encoded by the codon ugg) is an α-amino acid that is used in the biosynthesis of proteins. tryptophan has an α-amino group, an α-carboxylic acid group, and a side chain indole, demonstrating it as a non-polar, aromatic amino acid. tryptophan is critical in humans, but the body cannot synthesize it and therefore tryptophan must be obtained from the diet. tryptophan is also found to be a precursor to the neurotransmitters serotonin and melatonin.

in vitro

in previous studies, 5-hydroxy tryptophol was identified as a metabolite of tryptophan that was formed by the alcohol dehydrogenase-catalyzed reduction of the serotonin intermediate, 5-hydroxyindoleacetaldehyde. moreover, depending on the tissue nad/nadh ratio, the acetaldehyde intermediate could also be oxidized by aldehyde dehydrogenase to form 5-hydroxyindoleacetic acid. therefore, the ratio of 5-hydroxy tryptophol to 5-hydroxyindoleacetic acid could be used as a biomarker for recent alcohol consumption [1,2].

References

[1] yokoyama, m. t. and carlson, j.r. dissimilation of tryptophan and related indolic compounds by ruminal microorganisms in vitro. appl.microbiol. 27(3), 540-548 (1974).
[2] beck, o. ,stephanson, n.,btthcer, m., et al. biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct uplc-tandem ms and elisa methods. alcohol & alcoholism 42(4), 321-325 (2007).

5-HYDROXYTRYPTOPHOL Preparation Products And Raw materials

Raw materials

Preparation Products

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5-HYDROXYTRYPTOPHOL Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
ProdList
94657
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76
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
Fax
86-21-50328109
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3bsc@sina.com
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China
ProdList
15839
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Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
ProdList
32321
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50
Clearsynth Labs Limited
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+91-22-26355700
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+91-22-26355701
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info@clearsynth.com
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India
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Shanghai Macklin Biochemical Co.,Ltd.
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15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
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Cool Pharm, Ltd
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021-60455363 18019463053
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50966098
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sales@coolpharm.com
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China
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Zhengzhou Alfachem Co., Ltd.
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0371-53765687 18937137882
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QQ:2885373884
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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131957
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Wuhan EEChem Technologies Co., Ltd
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0711-3617768 13308685235
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0711-3616558
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lihongcai4360@sina.com
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China
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1374
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Aikon International Limited
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025-58851090 13611564524
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(6)02557626880
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lwan@aikonchem.com
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China
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15951
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View Lastest Price from 5-HYDROXYTRYPTOPHOL manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
5-Hydroxytryptophol 154-02-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000KG
Release date
2024-07-16
Career Henan Chemical Co
Product
5-HYDROXYTRYPTOPHOL 154-02-9
Price
US $0.01/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1kg; 100kg; 500kg
Release date
2019-12-24

154-02-9, 5-HYDROXYTRYPTOPHOLRelated Search:


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