5-HYDROXYTRYPTOPHOL

Product Name: 5-HYDROXYTRYPTOPHOL
CAS No.: 154-02-9
Chemical Name: 5-HYDROXYTRYPTOPHOL
Synonyms: NSC 84416;hydroxytryptophol;3-(2-Hydroxyethyl);5-HYDROXYTRYPTOPHOL;5-hydroxy-indole-3-ethano;5-HYDROXYINDOLE-3-ETHANOL;5-HYDROXYTRYPTOPHOL(5OHIEt);5-hydroxy-1h-indole-3-ethano;5-hydroxy-1h-indole-3-ethanol;1H-Indole-3-ethanol,5-hydroxy-
CBNumber: CB3250862
Molecular Formula: C10H11NO2
Formula Weight: 177.2
MOL File: 154-02-9.mol

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5-HYDROXYTRYPTOPHOL Property

Melting point:: 111-113°
Boiling point:: 435.2±30.0 °C(Predicted)
Density: 1.356±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 10.07±0.40(Predicted)
color: White to Light Red

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Safety

RTECS: NL8512500
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16114
Product name: 5-hydroxy Tryptophol
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 16114
Product name: 5-hydroxy Tryptophol
Purity: ≥98%
Packaging: 10mg
Price: $55
Updated: 2024/03/01

Cayman Chemical

Product number: 16114
Product name: 5-hydroxy Tryptophol
Purity: ≥98%
Packaging: 25mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 16114
Product name: 5-hydroxy Tryptophol
Purity: ≥98%
Packaging: 100mg
Price: $275
Updated: 2024/03/01

TRC

Product number: H976000
Product name: 5-HydroxyTryptophol
Packaging: 10mg
Price: $65
Updated: 2021/12/16

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5-HYDROXYTRYPTOPHOL Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Powder

Uses

A metabolite of Tryptophan (T947200).

Definition

ChEBI: 5-Hydroxytryptophol is a member of indoles.

Hazard

A reproductive hazard.

Biological Activity

5-hydroxy tryptophol is a metabolite of tryptophan.tryptophan (encoded by the codon ugg) is an α-amino acid that is used in the biosynthesis of proteins. tryptophan has an α-amino group, an α-carboxylic acid group, and a side chain indole, demonstrating it as a non-polar, aromatic amino acid. tryptophan is critical in humans, but the body cannot synthesize it and therefore tryptophan must be obtained from the diet. tryptophan is also found to be a precursor to the neurotransmitters serotonin and melatonin.

in vitro

in previous studies, 5-hydroxy tryptophol was identified as a metabolite of tryptophan that was formed by the alcohol dehydrogenase-catalyzed reduction of the serotonin intermediate, 5-hydroxyindoleacetaldehyde. moreover, depending on the tissue nad/nadh ratio, the acetaldehyde intermediate could also be oxidized by aldehyde dehydrogenase to form 5-hydroxyindoleacetic acid. therefore, the ratio of 5-hydroxy tryptophol to 5-hydroxyindoleacetic acid could be used as a biomarker for recent alcohol consumption [1,2].

References

[1] yokoyama, m. t. and carlson, j.r. dissimilation of tryptophan and related indolic compounds by ruminal microorganisms in vitro. appl.microbiol. 27(3), 540-548 (1974).
[2] beck, o. ,stephanson, n.,btthcer, m., et al. biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct uplc-tandem ms and elisa methods. alcohol & alcoholism 42(4), 321-325 (2007).

5-HYDROXYTRYPTOPHOL Preparation Products And Raw materials

Raw materials

5-Benzyloxyindole Ethanol Sodium Sodium borohydride Palladium Tetrahydrofuran Diethyl ether Lithium Aluminum Hydride Methanol Oxalyl chloride

Preparation Products

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5-HYDROXYTRYPTOPHOL Suppliers

Canada 2 China 54 Germany 1 India 2 Japan 1 Switzerland 3 United Kingdom 4 United States 16 Global 83

J & K SCIENTIFIC LTD.

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Zhengzhou Alfachem Co., Ltd.

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Amadis Chemical Company Limited

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Wuhan EEChem Technologies Co., Ltd

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View Lastest Price from 5-HYDROXYTRYPTOPHOL manufacturers

Career Henan Chemical Co

Product: 5-HYDROXYTRYPTOPHOL 154-02-9
Price: US $0.01/KG
Min. Order: 1KG
Purity: 95%-99%
Supply Ability: 1kg; 100kg； 500kg
Release date: 2019-12-24

154-02-9, 5-HYDROXYTRYPTOPHOLRelated Search:

Indometacin cinmetacin METHYL 5-BENZYLOXYINDOLE-3-ACETATE PROGLUMETACIN MALEATE 5-Methoxyindole-3-acetic acid 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Indorenate zidometacin Talmetacin 5-METHOXYTRYPTOPHOL 5-HYDROXYTRYPTOPHOL 5-HYDROXYINDOLE-3-ACETIC ACID 5-BENZYLOXYINDOLE-3-ACETIC ACID Acemetacin 5-Hydroxyindole 5-BENZYLOXYINDOLE-3-GLYOXYLIC ACID ETHYL ESTER 5-HYDROXYINDOLE-3-ACETIC ACID DICYCLOHEXYLAMMONIUM SALT niometacin

2-(5-HYDROXY-3-INDOLYL)ETHYL ALCOHOL

5-HYDROXYTRYPTOPHOL

5-HYDROXYINDOLE-3-ETHANOL

5-hydroxy-1h-indole-3-ethano

5-hydroxy-1h-indole-3-ethanol

1H-Indole-3-ethanol,5-hydroxy-

5-hydroxy-indole-3-ethano

hydroxytryptophol

5-hydroxytryptophol crystalline

5-Hydroxy-3-(2-hydroxyethyl)indole

NSC 84416

3-(2-hydroxyethyl)-1H-indol-5-ol

5-Hydroxy-3-(2-hydroxyethyl)-1H-indole

5-HYDROXYTRYPTOPHOL(5OHIEt)

3-(2-Hydroxyethyl)

DL-2-amino-3-(5-fluoro-3-indolyl)propionic acid

5-Hydroxytryptophol,Endogenous Metabolite,Inhibitor,5Hydroxytryptophol,5 Hydroxytryptophol,inhibit

154-02-9

Indoles and derivatives

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals