ChemicalBook > CAS DataBase List > 5-Hydroxyindole

5-Hydroxyindole

Product Name
5-Hydroxyindole
CAS No.
1953-54-4
Chemical Name
5-Hydroxyindole
Synonyms
1H-INDOL-5-OL;5-INDOLOL;5-Hydroxyindoline;NSC 87503;INDOL-5-OL;5-hdroxyindole;5-HYDROXYINDOLE;hydroxy-5indole;Hydroxy-5 indole;Hydroxyindole,98%
CBNumber
CB9151600
Molecular Formula
C8H7NO
Formula Weight
133.15
MOL File
1953-54-4.mol
More
Less

5-Hydroxyindole Property

Melting point:
106-108 °C(lit.)
Boiling point:
245.66°C (rough estimate)
Density 
1.1475 (rough estimate)
refractive index 
1.5260 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
38g/l
form 
Crystalline Needles or Powder
pka
9.98±0.40(Predicted)
color 
beige
Sensitive 
Light Sensitive
BRN 
112349
CAS DataBase Reference
1953-54-4(CAS DataBase Reference)
NIST Chemistry Reference
Indol-5-ol(1953-54-4)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
NM2430000
HazardClass 
IRRITANT, KEEP COLD
HS Code 
29339990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H31859
Product name
5-Hydroxyindole
Purity
97%
Packaging
1g
Price
$68.5
Updated
2024/03/01
TCI Chemical
Product number
H0252
Product name
5-Hydroxyindole
Purity
>98.0%(GC)
Packaging
100mg
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
H0252
Product name
5-Hydroxyindole
Purity
>98.0%(GC)
Packaging
1g
Price
$57
Updated
2024/03/01
Alfa Aesar
Product number
L00858
Product name
5-Hydroxyindole, 98+%
Packaging
1g
Price
$50.65
Updated
2024/03/01
Alfa Aesar
Product number
L00858
Product name
5-Hydroxyindole, 98+%
Packaging
5g
Price
$185.65
Updated
2024/03/01
More
Less

5-Hydroxyindole Chemical Properties,Usage,Production

Chemical Properties

beige to brown crystalline needles or powder

Uses

• ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6

Uses

5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.

Definition

ChEBI: 5-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. It has a role as a human metabolite.

Synthesis Reference(s)

Journal of the American Chemical Society, 76, p. 5579, 1954 DOI: 10.1021/ja01651a001
The Journal of Organic Chemistry, 49, p. 4833, 1984 DOI: 10.1021/jo00199a017

5-Hydroxyindole Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-Hydroxyindole Suppliers

Jiaxing Zhonghui Biotechnology Co. Ltd
Tel
17324007174
Email
jiangfeng2016@126.com
Country
China
ProdList
58
Advantage
55
Wuhan EnTai Technology Development Co,.Ltd
Tel
86-27-82330560
Fax
86-27-82330547
Email
2536851935@qq.com
Country
China
ProdList
347
Advantage
69
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
More
Less

View Lastest Price from 5-Hydroxyindole manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
5-Hydroxyindole 1953-54-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-22
Hebei Weibang Biotechnology Co., Ltd
Product
5-Hydroxyindole 1953-54-4
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
5-Hydroxyindole 1953-54-4
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21

1953-54-4, 5-HydroxyindoleRelated Search:


  • 5-Hydroxy-1H-indole
  • Hydroxy-5 indole
  • hydroxy-5indole
  • TIMTEC-BB SBB004214
  • 1H-INDOL-5-OL
  • 5-HYDROXYINDOLE
  • 5-INDOLOL
  • INDOL-5-OL
  • Hydroxyindole,98%
  • 5-hdroxyindole
  • 5-HYDROXYINDOLE 99%
  • 5-Hydroxyindole, 98+%
  • 5-HYDROXYINDOLE (5OHI)
  • 5-Hydroxyindole,97%
  • 5-Hydroxyindole,5-Hydroxyindole, 5-Indolol
  • 5-Hydroxyindole, 97% 1GR
  • 5-carboxylindoline 2,3-dihydro-1h-indole-5-carboxylic Acid Indoline-5-carboxylic acid in stock Factory
  • 5-Hydroxy-1H-indole 98%
  • NSC 87503
  • 5-Hydroxyindoline
  • 5-Hydroxyindole&gt
  • 5-Hydroxyindole ISO 9001:2015 REACH
  • 5-Hydroxyindole?New
  • 5-Hydroxyindole, ≥ 98.0%
  • 1953-54-4
  • 1593-54-4
  • 1953-94-4
  • Building Blocks
  • Indoles
  • Simple Indoles
  • Heterocyclic Building Blocks
  • Heterocycle-Indole series
  • Building Blocks
  • C7 to C9
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Indoles
  • Simple Indoles
  • pharmacetical
  • Indole
  • indole derivative
  • Indoles and derivatives
  • blocks
  • IndolesOxindoles