ChemicalBook > CAS DataBase List > 5-Hydroxyindole

5-Hydroxyindole

Product Name
5-Hydroxyindole
CAS No.
1953-54-4
Chemical Name
5-Hydroxyindole
Synonyms
1H-INDOL-5-OL;5-INDOLOL;5-Hydroxyindoline;NSC 87503;INDOL-5-OL;5-hdroxyindole;5-HYDROXYINDOLE;hydroxy-5indole;Hydroxy-5 indole;Hydroxyindole,98%
CBNumber
CB9151600
Molecular Formula
C8H7NO
Formula Weight
133.15
MOL File
1953-54-4.mol
More
Less

5-Hydroxyindole Property

Melting point:
106-108 °C(lit.)
Boiling point:
245.66°C (rough estimate)
Density 
1.1475 (rough estimate)
refractive index 
1.5260 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
38g/l
form 
Crystalline Needles or Powder
pka
9.98±0.40(Predicted)
color 
beige
Sensitive 
Light Sensitive
BRN 
112349
InChI
InChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
InChIKey
LMIQERWZRIFWNZ-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(O)C=C2)C=C1
CAS DataBase Reference
1953-54-4(CAS DataBase Reference)
NIST Chemistry Reference
Indol-5-ol(1953-54-4)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
NM2430000
HazardClass 
IRRITANT, KEEP COLD
HS Code 
29339990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H31859
Product name
5-Hydroxyindole
Purity
97%
Packaging
1g
Price
$68.5
Updated
2024/03/01
TCI Chemical
Product number
H0252
Product name
5-Hydroxyindole
Purity
>98.0%(GC)
Packaging
100mg
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
H0252
Product name
5-Hydroxyindole
Purity
>98.0%(GC)
Packaging
1g
Price
$57
Updated
2024/03/01
Alfa Aesar
Product number
L00858
Product name
5-Hydroxyindole, 98+%
Packaging
1g
Price
$50.65
Updated
2024/03/01
Alfa Aesar
Product number
L00858
Product name
5-Hydroxyindole, 98+%
Packaging
5g
Price
$185.65
Updated
2024/03/01
More
Less

5-Hydroxyindole Chemical Properties,Usage,Production

Chemical Properties

beige to brown crystalline needles or powder

Uses

• ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6

Uses

5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.

Definition

ChEBI: 5-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. It has a role as a human metabolite.

Synthesis Reference(s)

Journal of the American Chemical Society, 76, p. 5579, 1954 DOI: 10.1021/ja01651a001
The Journal of Organic Chemistry, 49, p. 4833, 1984 DOI: 10.1021/jo00199a017

5-Hydroxyindole Preparation Products And Raw materials

Raw materials

3-Methyl-4-nitrophenol potassium ferricyanide Palladium Benzyl bromide N,N-Dimethylformamide dimethyl acetal

Preparation Products

More
Less

5-Hydroxyindole Suppliers

Americas 1 Belgium 1 Canada 1 China 300 Europe 3 Germany 5 India 22 Japan 4 Slovakia 1 Switzerland 6 Ukraine 1 United Kingdom 18 United States 75 Global 438
Jiaxing Zhonghui Biotechnology Co. Ltd
Tel
17324007174
Email
jiangfeng2016@126.com
Country
China
ProdList
59
Advantage
55
Wuhan EnTai Technology Development Co,.Ltd
Tel
86-27-82330560
Fax
86-27-82330547
Email
2536851935@qq.com
Country
China
ProdList
347
Advantage
69
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9510
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9810
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
19951945301
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19185
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Chembon Pharmaceutical Co., Ltd.
Tel
028-84252981
Fax
+86-28-84252965
Email
sales@chembon.com.cn
Country
China
ProdList
814
Advantage
64
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Shanghai AmasPharm Co., Ltd.
Tel
021-54540637 18621091017
Fax
021-34978309
Email
sales@amaspharm.com
Country
China
ProdList
747
Advantage
62
Wuhan Arike Technology Co., Ltd.
Tel
027- 51832457 94518350
Fax
E-Mail Inquiry
Country
China
ProdList
746
Advantage
62
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Sphinx Scientific Laboratory (Tianjin) Co., Ltd.
Tel
022-66211289-843 13672102692
Fax
QQ：2377893365
Email
contact@sphinxpharm.com
Country
China
ProdList
361
Advantage
62
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
979
Advantage
62
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3203
Advantage
55
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Anhui Shite Pharmaceutical Technology Co., LTD
Tel
0555-8228058 13621628489
Fax
0512-63261912
Email
sales1@stepuppharm.com
Country
China
ProdList
229
Advantage
55
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098, 021-37212705 021-37212706, 13391256916
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
570
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Wuhan Taiyicheng Biopharmaceutical Co., Ltd.
Tel
027-88320699
Fax
027-88320962
Email
tycshyy@126.com
Country
China
ProdList
297
Advantage
66
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9478
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18021050169
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1972
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9893
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
More
Less

View Lastest Price from 5-Hydroxyindole manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
5-Hydroxyindole 1953-54-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-22
Wuhan Circle Star Chem-medical Technology Co.,Ltd
Product
5-Hydroxyindole 1953-54-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99
Supply Ability
1000
Release date
2025-01-23
Hebei Mujin Biotechnology Co.,Ltd
Product
5-Hydroxyindole 1953-54-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-09

1953-54-4, 5-HydroxyindoleRelated Search:

Indole-3-acetic acid Indole-3-butyric acid Chrysin Indometacin 5-HYDROXYOXINDOLE 2,3-DIHYDROINDOL-5-OL 5-Methoxyindole-3-carboxaldehyde 5,6-Dimethoxyindole 5-Methoxyindole 5-METHOXY-2-METHYLINDOLE 5-BENZYLOXYGRAMINE Melatonine DL-5-HYDROXYTRYPTOPHAN 5-Benzyloxyindole 5-Methoxytryptamine 7-HYDROXYINDOLE 5-METHOXY-DL-TRYPTOPHAN 4-HYDROXYINDOLE

  • 5-Hydroxy-1H-indole
  • Hydroxy-5 indole
  • hydroxy-5indole
  • TIMTEC-BB SBB004214
  • 1H-INDOL-5-OL
  • 5-HYDROXYINDOLE
  • 5-INDOLOL
  • INDOL-5-OL
  • Hydroxyindole,98%
  • 5-hdroxyindole
  • 5-HYDROXYINDOLE 99%
  • 5-Hydroxyindole, 98+%
  • 5-HYDROXYINDOLE (5OHI)
  • 5-Hydroxyindole,97%
  • 5-Hydroxyindole,5-Hydroxyindole, 5-Indolol
  • 5-Hydroxyindole, 97% 1GR
  • 5-carboxylindoline 2,3-dihydro-1h-indole-5-carboxylic Acid Indoline-5-carboxylic acid in stock Factory
  • 5-Hydroxy-1H-indole 98%
  • NSC 87503
  • 5-Hydroxyindoline
  • 5-Hydroxyindole&gt
  • 5-Hydroxyindole ISO 9001：2015 REACH
  • 5-Hydroxyindole?New
  • 5-Hydroxyindole, ≥ 98.0%
  • 1953-54-4
  • 1593-54-4
  • 1953-94-4
  • Building Blocks
  • Indoles
  • Simple Indoles
  • Heterocyclic Building Blocks
  • Heterocycle-Indole series
  • Building Blocks
  • C7 to C9
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Indoles
  • Simple Indoles
  • pharmacetical
  • Indole
  • indole derivative
  • Indoles and derivatives
  • blocks
  • IndolesOxindoles