ChemicalBook > CAS DataBase List > 5-METHOXY-2-METHYLINDOLE

5-METHOXY-2-METHYLINDOLE

Product Name
5-METHOXY-2-METHYLINDOLE
CAS No.
1076-74-0
Chemical Name
5-METHOXY-2-METHYLINDOLE
Synonyms
NSC 63817;AKOS JY2082626;5-Methoxy-2-methyindole;2-Methyl-5-Methoxyindole;5-METHOXY-2-METHYLINDOLE;Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole>5-Methoxy-2-methylindole 99%;1H-Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole, 99+%
CBNumber
CB8174569
Molecular Formula
C10H11NO
Formula Weight
161.2
MOL File
1076-74-0.mol
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5-METHOXY-2-METHYLINDOLE Property

Melting point:
86-88 °C (lit.)
Boiling point:
145 °C / 1.5mmHg
Density 
1.0840 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in methanol (very faint turbidity.)
form 
Crystalline Powder or Crystals
pka
17.28±0.30(Predicted)
color 
White to light beige
InChIKey
VSWGLJOQFUMFOQ-UHFFFAOYSA-N
CAS DataBase Reference
1076-74-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M15451
Product name
5-Methoxy-2-methylindole
Purity
99%
Packaging
1g
Price
$52.4
Updated
2024/03/01
Sigma-Aldrich
Product number
M15451
Product name
5-Methoxy-2-methylindole
Purity
99%
Packaging
5g
Price
$174
Updated
2024/03/01
TCI Chemical
Product number
M0730
Product name
5-Methoxy-2-methylindole
Purity
>99.0%(GC)
Packaging
1g
Price
$147
Updated
2024/03/01
TCI Chemical
Product number
M0730
Product name
5-Methoxy-2-methylindole
Purity
>99.0%(GC)
Packaging
5g
Price
$584
Updated
2024/03/01
Alfa Aesar
Product number
B21348
Product name
5-Methoxy-2-methylindole, 99+%
Packaging
1g
Price
$31.65
Updated
2024/03/01
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5-METHOXY-2-METHYLINDOLE Chemical Properties,Usage,Production

Description

5-methoxy-2-methylindole is a useful organic raw material. It can be used as the reactant in the preparation of indolylquinoxalines by condensation reactions, in preparation of alkylindoles via Ir-catalyzed reductive alkylation, in arylation reactions in the presence of a palladium acetate catalyst, in enantioselective Friedel-Crafts alkylation, as well as in stereo selective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. It is also employed in inhibiting the chlorinating activity of myeloperoxidase (MPO) and in the metabolic synthesis of acrylacetic acid anti-inflammatory synthesis.

Chemical Properties

white to light beige crystalline powder or

Uses

An indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid antiinflammatory synthesis.

Uses

reactant in preparation of indolylquinoxalines by condensation reactions1reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation2reactant in arylation reactions using a palladium acetate catalyst3reactant in enantioselective Friedel-Crafts alkylation4reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation5

Uses

It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.

Definition

ChEBI: 5-Methoxy-2-methyl-1H-indole is a member of indoles.

References

https://www.alfa.com/en/catalog/B21348/
http://www.sigmaaldrich.com/catalog/product/aldrich/m15451?lang=en&region=US
https://pubchem.ncbi.nlm.nih.gov/compound/5-Methoxy-2-methylindole#section=2D-Structure

5-METHOXY-2-METHYLINDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHOXY-2-METHYLINDOLE Suppliers

Heze Aiding Pharmaceutical Co., Ltd
Tel
17661365138
Email
17854177579@163.com
Country
China
ProdList
952
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17988
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
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View Lastest Price from 5-METHOXY-2-METHYLINDOLE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
5-Methoxy-2-methylindole 1076-74-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19
Nanjing jinheyou Trading Co., Ltd.
Product
5-METHOXY-2-METHYLINDOLE 1076-74-0
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
20kg/month
Release date
2019-12-20
Career Henan Chemical Co
Product
5-METHOXY-2-METHYLINDOLE 1076-74-0
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-22

1076-74-0, 5-METHOXY-2-METHYLINDOLERelated Search:


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