4-Methoxyphenylhydrazine hydrochloride

Product Name: 4-Methoxyphenylhydrazine hydrochloride
CAS No.: 19501-58-7
Chemical Name: 4-Methoxyphenylhydrazine hydrochloride
Synonyms: AURORA KA-1052;Indomethacin impurity 4;(4-methoxyanilino)azanium;4-Methoxyphenyhydrozine HCL;Indomethacin impurity 4 HCl;Indomethacin Impurity 1 HCl;p-anisidinoammonium chloride;4-METHOXYPHENYLHYDRAZINE HCL;4-ANISYLHYDRAZINE HYDROCHLORIDE;4-HYDRAZINOANISOLE HYDROCHLORIDE
CBNumber: CB9218707
Molecular Formula: C7H11ClN2O
Formula Weight: 174.63
MOL File: 19501-58-7.mol

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4-Methoxyphenylhydrazine hydrochloride Property

Melting point:: 160-162 °C (dec.)(lit.)
storage temp.: Keep Cold
solubility: DMSO (Slightly), Methanol (Slightly)
form: Powder, Crystals and/or Chunks
color: Slightly pink to gray to purple
Water Solubility: soluble
BRN: 3566583
Stability:: Light Sensitive
InChI: InChI=1S/C7H10N2O.ClH/c1-10-7-4-2-6(9-8)3-5-7;/h2-5,9H,8H2,1H3;1H
InChIKey: FQHCPFMTXFJZJS-UHFFFAOYSA-N
SMILES: C1(NN)=CC=C(OC)C=C1.Cl
CAS DataBase Reference: 19501-58-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 36/37-36-26
RIDADR: 2811
WGK Germany: 3
Hazard Note: Irritant/Harmful
HazardClass: IRRITANT, KEEP COLD
PackingGroup: III
HS Code: 29280090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral
Skin Sens. 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 152137
Product name: 4-Methoxyphenylhydrazine hydrochloride
Purity: 98%
Packaging: 10g
Price: $170
Updated: 2025/07/31

Sigma-Aldrich

Product number: 152137
Product name: 4-Methoxyphenylhydrazine hydrochloride
Purity: 98%
Packaging: 50g
Price: $352
Updated: 2025/07/31

TCI Chemical

Product number: M0637
Product name: 4-Methoxyphenylhydrazine Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: M0637
Product name: 4-Methoxyphenylhydrazine Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $162
Updated: 2025/07/31

TRC

Product number: M265880
Product name: 4-Methoxyphenylhydrazine Hydrochloride
Packaging: 5g
Price: $140
Updated: 2021/12/16

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4-Methoxyphenylhydrazine hydrochloride Chemical Properties,Usage,Production

Description

4-Methoxyphenylhydrazine hydrochloride is a kind of midbody that is mainly used for producing phenylhydrazine, and can also be used to make other Chemicals. The reparation technology of 4-Methoxyphenylhydrazine hydrochloride comprises aniline diazonium and benzene diazonium chloride diazo benzene chloride two-step process.

Chemical Properties

slightly pink to greyish-purple powder

Uses

4-Methoxyphenylhydrazine hydrochloride was used in the preparation of 5-cyano-3-(5-methoxy-2-methylindol-3-yl)-1,2,4-thiadiazole.

Synthesis

4-Methoxyphenylhydrazine hydrochloride Preparation Process: Take hydrochloric acid and sodium nitrite and add them sequentially to aniline, where the molar ratio of aniline to hydrochloric acid to sodium nitrite is 1:2.3 to 3.2:1 to 1.1, and sodium nitrite is added at 0 to 5°C. The reaction temperature is 0 to 22°C, and the reaction time is 30 to 90 minutes. Then add ammonium sulfite and hydrochloric acid according to a molar ratio to aniline of 1:2 to 3.5:2.5 to 3.0. After reduction, hydrolysis, and acidification, the product can be obtained by filtration or centrifugation.

References

[1] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 13, p. 3322 - 3336
[2] Journal of Heterocyclic Chemistry, 1995, vol. 32, # 1, p. 1 - 11
[3] Russian Chemical Bulletin, 2005, vol. 54, # 10, p. 2417 - 2424
[4] European Journal of Medicinal Chemistry, 2010, vol. 45, # 10, p. 4692 - 4696
[5] Journal of Organic Chemistry, 2011, vol. 76, # 13, p. 5295 - 5308

4-Methoxyphenylhydrazine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

1-(4-METHOXYPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBALDEHYDE 5-METHOXY-2-METHYLINDOLE

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4-Methoxyphenylhydrazine hydrochloride Suppliers

Americas 1 Austria 2 Belgium 2 China 338 Czech Republic 2 Europe 3 Germany 5 India 40 Italy 1 Japan 3 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 1 United Kingdom 16 United States 48 Global 468

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

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Alfa Aesar

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TAIYUAN RHF CO.,LTD.

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TCI (Shanghai) Development Co., Ltd.

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View Lastest Price from 4-Methoxyphenylhydrazine hydrochloride manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: 4-Methoxyphenylhydrazine hydrochloride 19501-58-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1
Release date: 2025-08-25

Chongqing Soarwin Technology Co., Ltd

Product: 4-Methoxyphenylhydrazine hydrochloride 19501-58-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2025-05-12

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Methoxyphenylhydrazine hydrochloride 19501-58-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-03

19501-58-7, 4-Methoxyphenylhydrazine hydrochlorideRelated Search:

1-Acetyl-2-phenylhydrazine (Trifluoromethoxy)benzene Phenylhydrazine hydrochloride 2-Ethylphenylhydrazine hydrochloride Anisole Topotecan hydrochloride p-Anisidine 4-Hydrazinylbenzoic acid p-Anisaldehyde HYDRAZINE 1,4-Butane sultone Glutacondianil hydrochloride 1,1,2-Trimethyl-1H-benz[e]indole 4-Benzyloxyphenylhydrazine hydrochloride 4-(Trifluoromethoxy)phenylhydrazine hydrochloride 3-Methoxyphenylhydrazine hydrochloride, 98+%,3-METHOXYPHENYLHYDRAZINE HYDROCHLORIDE 3,4-DIMETHOXYPHENYLHYDRAZINE HYDROCHLORIDE 5-amino-2-(2,6-dichloro-4-methoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one

4-METHOXYPHENYLHYDRAZINIUM CHLORIDE FOR

IndoMethacin iMpurity (4-Methoxyphenylhydrazine hydrochloride)

Hydrazine,(4-Methoxyphenyl)-, hydrochloride (1:1)

(4-methoxyphenyl)hydrazine dihydrochloride

4-Methoxyphenylhydrazinium chloride for synthesis

[(4-methoxyphenyl)amino]ammonium chloride

[(4-methoxyphenyl)amino]azanium chloride

p-anisidinoammonium chloride

Indomethacin impurity 4

P-METHOXY-PHENYLHYDRAZINE-HYDROCHLORIDE

P-METHOXYPHENYLHYDRAZINIUM CHLORIDE

PARA METHOXY PHENYL HYDRAZINE HYDROCHLORIDE

AURORA KA-1052

1-(4-METHOXYPHENYL)HYDRAZINE HYDROCHLORIDE

4-HYDRAZINOANISOLE HYDROCHLORIDE

4-METHOXYPHENYLHYDRAZINE HCL

4-METHOXYPHENYLHYDRAZINE HYDROCHLORIDE

4-METHOXYPHENYLHYDRAZINIUM HYDROCHLORIDE

4-ANISYLHYDRAZINE HYDROCHLORIDE

Hydrazine, (4-methoxyphenyl)-, monohydrochloride

4-Methoxyphenylhydrazine hydrochloride 98%

4-Methoxyphenylhydrazinehydrochloride98%

4-Methoxyphenylhydrazinehydrochloridel

p-Methoxy phenyl hydrazine hydrocloride

4-Methoxyphenyhydrozine HCL

4-Methoxyphenylhydrazine Hcl 98 %

4-Hydrazinoanisole hydrochloride, 4-Hydrazinophenyl methyl ether hydrochloride

4-Methoxyphenylhydrazine hydrochloride, 98% 10GR

4-MethoxyphenylhydrazineHydrochloride&gt

Indomethacin impurity 4 HCl

4-Methoxyphenylhydrazine hydrochloride ISO 9001：2015 REACH

(4-methoxyanilino)azanium

Indomethacin Impurity 1 HCl

4-Methoxyphenylhydrazine hydrochloride，97%

19501-58-7

19502-58-7

19501-59-7

C7H10N2O1

CH3OC6H4NHNH2HCl

C7H10N2OHCl

C7H10N2OHCI

Building Blocks

Organic Building Blocks

Nitrogen Compounds

Hydrazines

Phenylhydrazine

Hydrazines

Nitrogen Compounds

Organic Building Blocks

Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes

Amines and Anilines