1,4-Butane sultone
- Product Name
- 1,4-Butane sultone
- CAS No.
- 1633-83-6
- Chemical Name
- 1,4-Butane sultone
- Synonyms
- butanesultone;1,4-BUTANE SULTON;-Sultone;1,4-Butane;butanesulfone;1,4-Butane suL;JACS-1633-83-6;δ-Valerosultone;1,4-Butylsultone;1,4-BUTANESULPHONE
- CBNumber
- CB1497155
- Molecular Formula
- C4H8O3S
- Formula Weight
- 136.17
- MOL File
- 1633-83-6.mol
1,4-Butane sultone Property
- Melting point:
- 12-15 °C (lit.)
- Boiling point:
- >165 °C/25 mmHg (lit.)
- Density
- 1.331 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.464(lit.)
- Flash point:
- >230 °F
- storage temp.
- Store below +30°C.
- solubility
- 54g/l (decomposition)
- form
- Liquid
- color
- Clear colorless to yellow
- Water Solubility
- 54 g/L (20 ºC) decomposes
- Sensitive
- Moisture Sensitive
- BRN
- 110588
- InChIKey
- MHYFEEDKONKGEB-UHFFFAOYSA-N
- CAS DataBase Reference
- 1633-83-6(CAS DataBase Reference)
- EPA Substance Registry System
- 1,2-Oxathiane, 2,2-dioxide (1633-83-6)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-40-68-20/21/22
- Safety Statements
- 22-36/37-45-36
- RIDADR
- 2810
- WGK Germany
- 3
- RTECS
- RP4300000
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29349990
- Hazardous Substances Data
- 1633-83-6(Hazardous Substances Data)
- Toxicity
- LD50 orally in Rabbit: 500 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B85501
- Product name
- 1,4-Butane sultone
- Purity
- ≥99%
- Packaging
- 25g
- Price
- $62.7
- Updated
- 2024/03/01
- Product number
- B85501
- Product name
- 1,4-Butane sultone
- Purity
- ≥99%
- Packaging
- 100g
- Price
- $145
- Updated
- 2024/03/01
- Product number
- 8.20665
- Product name
- 1,4-Butane sultone
- Purity
- for synthesis
- Packaging
- 50mL
- Price
- $112
- Updated
- 2024/03/01
- Product number
- 8.20665
- Product name
- 1,4-Butane sultone
- Purity
- for synthesis
- Packaging
- 250ML
- Price
- $342
- Updated
- 2024/03/01
- Product number
- B0136
- Product name
- 1,4-Butane sultone
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $67
- Updated
- 2024/03/01
1,4-Butane sultone Chemical Properties,Usage,Production
Description
1,4-Butane sultone is an impurity in sulfobutyl ether β-cyclodextrin (SBE-β-CD), and has been reported to be a weak carcinogen. 1,4-Butane sultone can be used for preparation of Br?nsted acidic ionic liquids and the ionic liquid is green, highly water soluble, thermally stable, specific and catalytically stable, and can be used for the preparation of symmetrical 3,3'-diaryloxyoctanone compounds[1-2].
Chemical Properties
Butanesultone is a viscous, clear, colourless – or yellowish/brown – and odourless liquid. When heated, vapours of butanesultone are known to form explosive mixtures with air and are reported to cause explosion hazards.
Uses
1,4-Butane Sultone is an alkylating agent with weak carcinogenic activity.
Uses
1,4-Butane sultone can be employed as a reactant in the preparation of conjugated polymers which include polybetaine, poly[2-ethynyl-N-(4-sulfobutyl)pyridinium betaine] (PESPB).
It can also be used in the preparation of Bronsted acid catalysts such as 4-(succinimido)-1-butane sulfonic acid and poly(4-vinylpyridinium butane sulfonic acid) hydrogen sulfate. These catalysts facilitate the synthesis of 1-amidoalkyl-2-naphthols, substituted quinolines, and pyrano[4,3-b]pyran derivatives.
Application
1,4-Butane sultone is an intermediate widely used for sulfonated surfactants.It is also applied in photo development and electroplating.It is used as the Intermediate for the production of APIs.It used in sulfobutylether-β-cyclodextrin（SEBCD).
Safety Profile
Suspected carcinogen with experimental tumorigenic data. Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. See also SULFONATES. When heated to decomposition it emits toxic fumes of SOx
Synthesis
Performing sulfonation on 3-butylene-1-alcohol or 3-butylene-1-chlorine serving as a raw material and a sulfonating agent under the oxidation-reduction of an initiator;performing acidification after the reaction is finished;performing lactonization by high vacuum dehydration cyclization and azeotropic dehydration cyclization;and finally refining to obtain a 1,4-butane sultone finished product.
References
[1] LAYLA A. TAIB; Mosadegh K. Introduction of novel br?nsted acidic ionic liquids with perchlorate counter-anion for one-pot synthesis of symmetric 3,3′-diaryloxindoles[J]. Research on Chemical Intermediates, 2021. DOI:10.1007/s11164-021-04419-5.
[2] MENG WANG. Determination of Low-ppm Levels of 1,4-Butane Sultone in Sulfobutyl Ether β-Cyclodextrin Using Liquid–Liquid Extraction and GC–MS[J]. Chromatographia, 2012. DOI:10.1007/s10337-012-2275-8.
1,4-Butane sultone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,4-Butane sultone manufacturers
- Product
- 1,4-Butane sultone 1633-83-6
- Price
- US $99.00-66.00/kg
- Min. Order
- 0.0010000000474974513kg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-19
- Product
- 1,4-Butane sultone 1633-83-6
- Price
- US $85.00-35.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-24
- Product
- 1,4-BUTANE SULTONE 1633-83-6
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 20tons
- Release date
- 2024-09-24