1,4-Butane sultone
- Product Name
- 1,4-Butane sultone
- CAS No.
- 1633-83-6
- Chemical Name
- 1,4-Butane sultone
- Synonyms
- butanesultone;1,4-BUTANE SULTON;-Sultone;1,4-Butane;butanesulfone;1,4-Butane suL;JACS-1633-83-6;δ-Valerosultone;1,4-Butylsultone;1,4-BUTANESULPHONE
- CBNumber
- CB1497155
- Molecular Formula
- C4H8O3S
- Formula Weight
- 136.17
- MOL File
- 1633-83-6.mol
1,4-Butane sultone Property
- Melting point:
- 12-15 °C (lit.)
- Boiling point:
- >165 °C/25 mmHg (lit.)
- Density
- 1.331 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.464(lit.)
- Flash point:
- >230 °F
- storage temp.
- Store below +30°C.
- solubility
- 54g/l (decomposition)
- form
- Liquid
- color
- Clear colorless to yellow
- Water Solubility
- 54 g/L (20 ºC) decomposes
- Sensitive
- Moisture Sensitive
- BRN
- 110588
- InChIKey
- MHYFEEDKONKGEB-UHFFFAOYSA-N
- CAS DataBase Reference
- 1633-83-6(CAS DataBase Reference)
- EPA Substance Registry System
- 1,2-Oxathiane, 2,2-dioxide (1633-83-6)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-40-68-20/21/22
- Safety Statements
- 22-36/37-45-36
- RIDADR
- 2810
- WGK Germany
- 3
- RTECS
- RP4300000
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29349990
- Hazardous Substances Data
- 1633-83-6(Hazardous Substances Data)
- Toxicity
- LD50 orally in Rabbit: 500 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B85501
- Product name
- 1,4-Butane sultone
- Purity
- ≥99%
- Packaging
- 25g
- Price
- $62.7
- Updated
- 2024/03/01
- Product number
- B85501
- Product name
- 1,4-Butane sultone
- Purity
- ≥99%
- Packaging
- 100g
- Price
- $145
- Updated
- 2024/03/01
- Product number
- 8.20665
- Product name
- 1,4-Butane sultone
- Purity
- for synthesis
- Packaging
- 50mL
- Price
- $112
- Updated
- 2024/03/01
- Product number
- 8.20665
- Product name
- 1,4-Butane sultone
- Purity
- for synthesis
- Packaging
- 250ML
- Price
- $342
- Updated
- 2024/03/01
- Product number
- B0136
- Product name
- 1,4-Butane sultone
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $67
- Updated
- 2024/03/01
1,4-Butane sultone Chemical Properties,Usage,Production
Description
1,4-Butane sultone is an impurity in sulfobutyl ether β-cyclodextrin (SBE-β-CD), and has been reported to be a weak carcinogen. 1,4-Butane sultone can be used for preparation of Br?nsted acidic ionic liquids and the ionic liquid is green, highly water soluble, thermally stable, specific and catalytically stable, and can be used for the preparation of symmetrical 3,3'-diaryloxyoctanone compounds[1-2].
Chemical Properties
Butanesultone is a viscous, clear, colourless – or yellowish/brown – and odourless liquid. When heated, vapours of butanesultone are known to form explosive mixtures with air and are reported to cause explosion hazards.
Uses
1,4-Butane Sultone is an alkylating agent with weak carcinogenic activity.
Uses
1,4-Butane sultone can be employed as a reactant in the preparation of conjugated polymers which include polybetaine, poly[2-ethynyl-N-(4-sulfobutyl)pyridinium betaine] (PESPB).
It can also be used in the preparation of Bronsted acid catalysts such as 4-(succinimido)-1-butane sulfonic acid and poly(4-vinylpyridinium butane sulfonic acid) hydrogen sulfate. These catalysts facilitate the synthesis of 1-amidoalkyl-2-naphthols, substituted quinolines, and pyrano[4,3-b]pyran derivatives.
Application
1,4-Butane sultone is an intermediate widely used for sulfonated surfactants.It is also applied in photo development and electroplating.It is used as the Intermediate for the production of APIs.It used in sulfobutylether-β-cyclodextrin（SEBCD).
Safety Profile
Suspected carcinogen with experimental tumorigenic data. Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. See also SULFONATES. When heated to decomposition it emits toxic fumes of SOx
Synthesis
Performing sulfonation on 3-butylene-1-alcohol or 3-butylene-1-chlorine serving as a raw material and a sulfonating agent under the oxidation-reduction of an initiator;performing acidification after the reaction is finished;performing lactonization by high vacuum dehydration cyclization and azeotropic dehydration cyclization;and finally refining to obtain a 1,4-butane sultone finished product.
References
[1] LAYLA A. TAIB; Mosadegh K. Introduction of novel br?nsted acidic ionic liquids with perchlorate counter-anion for one-pot synthesis of symmetric 3,3′-diaryloxindoles[J]. Research on Chemical Intermediates, 2021. DOI:10.1007/s11164-021-04419-5.
[2] MENG WANG. Determination of Low-ppm Levels of 1,4-Butane Sultone in Sulfobutyl Ether β-Cyclodextrin Using Liquid–Liquid Extraction and GC–MS[J]. Chromatographia, 2012. DOI:10.1007/s10337-012-2275-8.
1,4-Butane sultone Preparation Products And Raw materials
Raw materials
Preparation Products
1,4-Butane sultone Suppliers
- Tel
- 0512-52299299-131 17321661701
- zhurz@hopaxcs.com
- Country
- China
- ProdList
- 11
- Advantage
- 58
- Tel
- +86-027-85583407 +86-13554014698
- Fax
- +86-27-85804899
- purchase_peng@brightchemical.com.cn
- Country
- China
- ProdList
- 63
- Advantage
- 58
- Tel
- 027-63496417 13007129042
- Fax
- 13476107660
- 3294393103@qq.com
- Country
- China
- ProdList
- 296
- Advantage
- 58
- Tel
- 18986168071
- Fax
- 027-88121016
- 18986168071@163.com
- Country
- China
- ProdList
- 80
- Advantage
- 55
- Tel
- 027-82333386 13669024603
- Fax
- 86-027-82333386
- 617019505@qq.com
- Country
- China
- ProdList
- 253
- Advantage
- 58
- Tel
- 021-58957966 18930537195
- Fax
- 021-60899437
- wouchina@126.com
- Country
- China
- ProdList
- 3027
- Advantage
- 58
- Tel
- 15253208962
- sddjrhhgyl@126.com
- Country
- China
- ProdList
- 664
- Advantage
- 58
- Tel
- 188-88295188 15265310975
- Fax
- +86-531-88999750
- chen@chemwww.com
- Country
- China
- ProdList
- 4635
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 010-89508211 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
- ProdList
- 8418
- Advantage
- 55
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44688
- Advantage
- 61
- Tel
- 010-82967028 13552068683
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12390
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9514
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14103
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11655
- Advantage
- 64
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9809
- Advantage
- 59
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 19179
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 15527768850
- 1791901229@qq.com
- Country
- China
- ProdList
- 8837
- Advantage
- 52
- Tel
- 010-82954736 13391601435
- sales@isomersyn.com
- Country
- China
- ProdList
- 3295
- Advantage
- 57
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18738
- Advantage
- 57
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9815
- Advantage
- 79
- Tel
- 021-51613915-820 13611835272
- Fax
- 021 51613951
- mmwang@sunwaypharm.cn
- Country
- China
- ProdList
- 9734
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0370-2785118 17550508557
- Fax
- QQ：3470079902
- 675141927@qq.com
- Country
- China
- ProdList
- 3203
- Advantage
- 55
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4940
- Advantage
- 60
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 0755-4000505016 13380397412
- Fax
- 0755 28094224
- 3001272453@qq.com
- Country
- China
- ProdList
- 5047
- Advantage
- 50
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- 400-810-7969 010-59572699
- Fax
- 010-59572688
- ningzi.li@inno-chem.com.cn
- Country
- China
- ProdList
- 6134
- Advantage
- 55
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9458
- Advantage
- 58
- Tel
- +86-21-60341587
- Fax
- +86-21-61294319
- sales@topbiochem.com
- Country
- China
- ProdList
- 6175
- Advantage
- 58
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 400-400-6206333 18521732826
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-61552785
- Fax
- 021-55660885
- sales@shshiji.com
- Country
- China
- ProdList
- 9545
- Advantage
- 55
- Tel
- 028-85122536 15928766785
- Fax
- QQ961458712
- wupengcheng@astatech.cn
- Country
- China
- ProdList
- 2001
- Advantage
- 55
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 86-13605431940 13605431940
- Fax
- 0086-0543-2240079
- zpmxchemical@126.com
- Country
- China
- ProdList
- 1999
- Advantage
- 62
- Tel
- 0570-3066667
- Fax
- 0570-3063388
- Country
- China
- ProdList
- 3930
- Advantage
- 58
- Tel
- 0535-6101880
- Fax
- 0535-6386989
- liutao@valiant-cn.com
- Country
- China
- ProdList
- 282
- Advantage
- 60
- Tel
- 400-8706899
- Fax
- 400-8706899
- hysj_bj.com
- Country
- China
- ProdList
- 3583
- Advantage
- 55
View Lastest Price from 1,4-Butane sultone manufacturers
- Product
- 1,4-Butane sultone 1633-83-6
- Price
- US $99.00-66.00/kg
- Min. Order
- 0.0010000000474974513kg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-19
- Product
- 1,4-Butane sultone 1633-83-6
- Price
- US $85.00-35.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-24
- Product
- 1,4-BUTANE SULTONE 1633-83-6
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 20tons
- Release date
- 2024-09-24