ChemicalBook > CAS DataBase List > 5-METHOXY-2-METHYLINDOLE

5-METHOXY-2-METHYLINDOLE

Product Name
5-METHOXY-2-METHYLINDOLE
CAS No.
1076-74-0
Chemical Name
5-METHOXY-2-METHYLINDOLE
Synonyms
NSC 63817;AKOS JY2082626;5-Methoxy-2-methyindole;2-Methyl-5-Methoxyindole;5-METHOXY-2-METHYLINDOLE;Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole>5-Methoxy-2-methylindole 99%;1H-Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole, 99+%
CBNumber
CB8174569
Molecular Formula
C10H11NO
Formula Weight
161.2
MOL File
1076-74-0.mol
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5-METHOXY-2-METHYLINDOLE Property

Melting point:
86-88 °C (lit.)
Boiling point:
145 °C / 1.5mmHg
Density 
1.0840 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in methanol (very faint turbidity.)
form 
Crystalline Powder or Crystals
pka
17.28±0.30(Predicted)
color 
White to light beige
InChIKey
VSWGLJOQFUMFOQ-UHFFFAOYSA-N
CAS DataBase Reference
1076-74-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M15451
Product name
5-Methoxy-2-methylindole
Purity
99%
Packaging
1g
Price
$52.4
Updated
2024/03/01
Sigma-Aldrich
Product number
M15451
Product name
5-Methoxy-2-methylindole
Purity
99%
Packaging
5g
Price
$174
Updated
2024/03/01
TCI Chemical
Product number
M0730
Product name
5-Methoxy-2-methylindole
Purity
>99.0%(GC)
Packaging
1g
Price
$147
Updated
2024/03/01
TCI Chemical
Product number
M0730
Product name
5-Methoxy-2-methylindole
Purity
>99.0%(GC)
Packaging
5g
Price
$584
Updated
2024/03/01
Alfa Aesar
Product number
B21348
Product name
5-Methoxy-2-methylindole, 99+%
Packaging
1g
Price
$31.65
Updated
2024/03/01
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5-METHOXY-2-METHYLINDOLE Chemical Properties,Usage,Production

Description

5-methoxy-2-methylindole is a useful organic raw material. It can be used as the reactant in the preparation of indolylquinoxalines by condensation reactions, in preparation of alkylindoles via Ir-catalyzed reductive alkylation, in arylation reactions in the presence of a palladium acetate catalyst, in enantioselective Friedel-Crafts alkylation, as well as in stereo selective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. It is also employed in inhibiting the chlorinating activity of myeloperoxidase (MPO) and in the metabolic synthesis of acrylacetic acid anti-inflammatory synthesis.

Chemical Properties

white to light beige crystalline powder or

Uses

An indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid antiinflammatory synthesis.

Uses

reactant in preparation of indolylquinoxalines by condensation reactions1reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation2reactant in arylation reactions using a palladium acetate catalyst3reactant in enantioselective Friedel-Crafts alkylation4reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation5

Uses

It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.

Definition

ChEBI: 5-Methoxy-2-methyl-1H-indole is a member of indoles.

References

https://www.alfa.com/en/catalog/B21348/
http://www.sigmaaldrich.com/catalog/product/aldrich/m15451?lang=en&region=US
https://pubchem.ncbi.nlm.nih.gov/compound/5-Methoxy-2-methylindole#section=2D-Structure

5-METHOXY-2-METHYLINDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHOXY-2-METHYLINDOLE Suppliers

Maybridge Chemical Co., Ltd.
Tel
--
Fax
--
Country
Belgium
ProdList
6293
Advantage
73
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
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View Lastest Price from 5-METHOXY-2-METHYLINDOLE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
5-METHOXY-2-METHYLINDOLE 1076-74-0
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-07-07
Henan Aochuang Chemical Co.,Ltd.
Product
5-Methoxy-2-methylindole 1076-74-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19
Nanjing jinheyou Trading Co., Ltd.
Product
5-METHOXY-2-METHYLINDOLE 1076-74-0
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
20kg/month
Release date
2019-12-20

1076-74-0, 5-METHOXY-2-METHYLINDOLERelated Search:


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