5-Hydroxyindole
- Product Name
- 5-Hydroxyindole
- CAS No.
- 1953-54-4
- Chemical Name
- 5-Hydroxyindole
- Synonyms
- 1H-INDOL-5-OL;5-INDOLOL;5-Hydroxyindoline;NSC 87503;INDOL-5-OL;5-hdroxyindole;5-HYDROXYINDOLE;hydroxy-5indole;Hydroxy-5 indole;Hydroxyindole,98%
- CBNumber
- CB9151600
- Molecular Formula
- C8H7NO
- Formula Weight
- 133.15
- MOL File
- 1953-54-4.mol
5-Hydroxyindole Property
- Melting point:
- 106-108 °C(lit.)
- Boiling point:
- 245.66°C (rough estimate)
- Density
- 1.1475 (rough estimate)
- refractive index
- 1.5260 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- 38g/l
- form
- Crystalline Needles or Powder
- pka
- 9.98±0.40(Predicted)
- color
- beige
- Sensitive
- Light Sensitive
- BRN
- 112349
- CAS DataBase Reference
- 1953-54-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Indol-5-ol(1953-54-4)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- NM2430000
- HazardClass
- IRRITANT, KEEP COLD
- HS Code
- 29339990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H31859
- Product name
- 5-Hydroxyindole
- Purity
- 97%
- Packaging
- 1g
- Price
- $68.5
- Updated
- 2024/03/01
- Product number
- H0252
- Product name
- 5-Hydroxyindole
- Purity
- >98.0%(GC)
- Packaging
- 100mg
- Price
- $18
- Updated
- 2024/03/01
- Product number
- H0252
- Product name
- 5-Hydroxyindole
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $57
- Updated
- 2024/03/01
- Product number
- L00858
- Product name
- 5-Hydroxyindole, 98+%
- Packaging
- 1g
- Price
- $50.65
- Updated
- 2024/03/01
- Product number
- L00858
- Product name
- 5-Hydroxyindole, 98+%
- Packaging
- 5g
- Price
- $185.65
- Updated
- 2024/03/01
5-Hydroxyindole Chemical Properties,Usage,Production
Chemical Properties
beige to brown crystalline needles or powder
Uses
• ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6
Uses
5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.
Definition
ChEBI: 5-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. It has a role as a human metabolite.
Synthesis Reference(s)
Journal of the American Chemical Society, 76, p. 5579, 1954 DOI: 10.1021/ja01651a001
The Journal of Organic Chemistry, 49, p. 4833, 1984 DOI: 10.1021/jo00199a017
5-Hydroxyindole Preparation Products And Raw materials
Raw materials
Preparation Products
5-Hydroxyindole Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
- --
- Fax
- --
- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from 5-Hydroxyindole manufacturers
- Product
- 5-Hydroxyindole 1953-54-4
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-22
- Product
- 5-Hydroxyindole 1953-54-4
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-24
- Product
- 5-Hydroxyindole 1953-54-4
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.9
- Supply Ability
- 1 ton
- Release date
- 2024-08-21