ChemicalBook > CAS DataBase List > 5-HYDROXYTRYPTOPHOL

5-HYDROXYTRYPTOPHOL

Product Name
5-HYDROXYTRYPTOPHOL
CAS No.
154-02-9
Chemical Name
5-HYDROXYTRYPTOPHOL
Synonyms
NSC 84416;hydroxytryptophol;3-(2-Hydroxyethyl);5-HYDROXYTRYPTOPHOL;5-hydroxy-indole-3-ethano;5-HYDROXYINDOLE-3-ETHANOL;5-HYDROXYTRYPTOPHOL(5OHIEt);5-hydroxy-1h-indole-3-ethano;5-hydroxy-1h-indole-3-ethanol;1H-Indole-3-ethanol,5-hydroxy-
CBNumber
CB3250862
Molecular Formula
C10H11NO2
Formula Weight
177.2
MOL File
154-02-9.mol
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5-HYDROXYTRYPTOPHOL Property

Melting point:
111-113°
Boiling point:
435.2±30.0 °C(Predicted)
Density 
1.356±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
10.07±0.40(Predicted)
color 
White to Light Red
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Safety

RTECS 
NL8512500
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16114
Product name
5-hydroxy Tryptophol
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
16114
Product name
5-hydroxy Tryptophol
Purity
≥98%
Packaging
10mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
16114
Product name
5-hydroxy Tryptophol
Purity
≥98%
Packaging
25mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
16114
Product name
5-hydroxy Tryptophol
Purity
≥98%
Packaging
100mg
Price
$275
Updated
2024/03/01
TRC
Product number
H976000
Product name
5-HydroxyTryptophol
Packaging
10mg
Price
$65
Updated
2021/12/16
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5-HYDROXYTRYPTOPHOL Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Powder

Uses

A metabolite of Tryptophan (T947200).

Definition

ChEBI: 5-Hydroxytryptophol is a member of indoles.

Hazard

A reproductive hazard.

Biological Activity

5-hydroxy tryptophol is a metabolite of tryptophan.tryptophan (encoded by the codon ugg) is an α-amino acid that is used in the biosynthesis of proteins. tryptophan has an α-amino group, an α-carboxylic acid group, and a side chain indole, demonstrating it as a non-polar, aromatic amino acid. tryptophan is critical in humans, but the body cannot synthesize it and therefore tryptophan must be obtained from the diet. tryptophan is also found to be a precursor to the neurotransmitters serotonin and melatonin.

in vitro

in previous studies, 5-hydroxy tryptophol was identified as a metabolite of tryptophan that was formed by the alcohol dehydrogenase-catalyzed reduction of the serotonin intermediate, 5-hydroxyindoleacetaldehyde. moreover, depending on the tissue nad/nadh ratio, the acetaldehyde intermediate could also be oxidized by aldehyde dehydrogenase to form 5-hydroxyindoleacetic acid. therefore, the ratio of 5-hydroxy tryptophol to 5-hydroxyindoleacetic acid could be used as a biomarker for recent alcohol consumption [1,2].

References

[1] yokoyama, m. t. and carlson, j.r. dissimilation of tryptophan and related indolic compounds by ruminal microorganisms in vitro. appl.microbiol. 27(3), 540-548 (1974).
[2] beck, o. ,stephanson, n.,btthcer, m., et al. biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct uplc-tandem ms and elisa methods. alcohol & alcoholism 42(4), 321-325 (2007).

5-HYDROXYTRYPTOPHOL Preparation Products And Raw materials

Raw materials

5-Benzyloxyindole Ethanol Sodium Sodium borohydride Palladium Tetrahydrofuran Diethyl ether Lithium Aluminum Hydride Methanol Oxalyl chloride

Preparation Products

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View Lastest Price from 5-HYDROXYTRYPTOPHOL manufacturers

Career Henan Chemical Co
Product
5-HYDROXYTRYPTOPHOL 154-02-9
Price
US $0.01/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1kg; 100kg； 500kg
Release date
2019-12-24

154-02-9, 5-HYDROXYTRYPTOPHOLRelated Search:

Indometacin cinmetacin METHYL 5-BENZYLOXYINDOLE-3-ACETATE PROGLUMETACIN MALEATE 5-Methoxyindole-3-acetic acid 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID Indorenate zidometacin Talmetacin 5-METHOXYTRYPTOPHOL 5-HYDROXYTRYPTOPHOL 5-HYDROXYINDOLE-3-ACETIC ACID 5-BENZYLOXYINDOLE-3-ACETIC ACID Acemetacin 5-Hydroxyindole 5-BENZYLOXYINDOLE-3-GLYOXYLIC ACID ETHYL ESTER 5-HYDROXYINDOLE-3-ACETIC ACID DICYCLOHEXYLAMMONIUM SALT niometacin

  • 2-(5-HYDROXY-3-INDOLYL)ETHYL ALCOHOL
  • 5-HYDROXYTRYPTOPHOL
  • 5-HYDROXYINDOLE-3-ETHANOL
  • 5-hydroxy-1h-indole-3-ethano
  • 5-hydroxy-1h-indole-3-ethanol
  • 1H-Indole-3-ethanol,5-hydroxy-
  • 5-hydroxy-indole-3-ethano
  • hydroxytryptophol
  • 5-hydroxytryptophol crystalline
  • 5-Hydroxy-3-(2-hydroxyethyl)indole
  • NSC 84416
  • 3-(2-hydroxyethyl)-1H-indol-5-ol
  • 5-Hydroxy-3-(2-hydroxyethyl)-1H-indole
  • 5-HYDROXYTRYPTOPHOL(5OHIEt)
  • 3-(2-Hydroxyethyl)
  • DL-2-amino-3-(5-fluoro-3-indolyl)propionic acid
  • 5-Hydroxytryptophol,Endogenous Metabolite,Inhibitor,5Hydroxytryptophol,5 Hydroxytryptophol,inhibit
  • 154-02-9
  • Indoles and derivatives
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals