5-HYDROXYTRYPTOPHOL
- Product Name
- 5-HYDROXYTRYPTOPHOL
- CAS No.
- 154-02-9
- Chemical Name
- 5-HYDROXYTRYPTOPHOL
- Synonyms
- NSC 84416;hydroxytryptophol;3-(2-Hydroxyethyl);5-HYDROXYTRYPTOPHOL;5-hydroxy-indole-3-ethano;5-HYDROXYINDOLE-3-ETHANOL;5-HYDROXYTRYPTOPHOL(5OHIEt);5-hydroxy-1h-indole-3-ethano;5-hydroxy-1h-indole-3-ethanol;1H-Indole-3-ethanol,5-hydroxy-
- CBNumber
- CB3250862
- Molecular Formula
- C10H11NO2
- Formula Weight
- 177.2
- MOL File
- 154-02-9.mol
5-HYDROXYTRYPTOPHOL Property
- Melting point:
- 111-113°
- Boiling point:
- 435.2±30.0 °C(Predicted)
- Density
- 1.356±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 10.07±0.40(Predicted)
- color
- White to Light Red
Safety
- RTECS
- NL8512500
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 16114
- Product name
- 5-hydroxy Tryptophol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 16114
- Product name
- 5-hydroxy Tryptophol
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $55
- Updated
- 2024/03/01
- Product number
- 16114
- Product name
- 5-hydroxy Tryptophol
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 16114
- Product name
- 5-hydroxy Tryptophol
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $275
- Updated
- 2024/03/01
- Product number
- H976000
- Product name
- 5-HydroxyTryptophol
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
5-HYDROXYTRYPTOPHOL Chemical Properties,Usage,Production
Chemical Properties
Off-White Crystalline Powder
Uses
A metabolite of Tryptophan (T947200).
Definition
ChEBI: 5-Hydroxytryptophol is a member of indoles.
Hazard
A reproductive hazard.
Biological Activity
5-hydroxy tryptophol is a metabolite of tryptophan.tryptophan (encoded by the codon ugg) is an α-amino acid that is used in the biosynthesis of proteins. tryptophan has an α-amino group, an α-carboxylic acid group, and a side chain indole, demonstrating it as a non-polar, aromatic amino acid. tryptophan is critical in humans, but the body cannot synthesize it and therefore tryptophan must be obtained from the diet. tryptophan is also found to be a precursor to the neurotransmitters serotonin and melatonin.
in vitro
in previous studies, 5-hydroxy tryptophol was identified as a metabolite of tryptophan that was formed by the alcohol dehydrogenase-catalyzed reduction of the serotonin intermediate, 5-hydroxyindoleacetaldehyde. moreover, depending on the tissue nad/nadh ratio, the acetaldehyde intermediate could also be oxidized by aldehyde dehydrogenase to form 5-hydroxyindoleacetic acid. therefore, the ratio of 5-hydroxy tryptophol to 5-hydroxyindoleacetic acid could be used as a biomarker for recent alcohol consumption [1,2].
References
[1] yokoyama, m. t. and carlson, j.r. dissimilation of tryptophan and related indolic compounds by ruminal microorganisms in vitro. appl.microbiol. 27(3), 540-548 (1974).
[2] beck, o. ,stephanson, n.,btthcer, m., et al. biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct uplc-tandem ms and elisa methods. alcohol & alcoholism 42(4), 321-325 (2007).
5-HYDROXYTRYPTOPHOL Preparation Products And Raw materials
Raw materials
Preparation Products
5-HYDROXYTRYPTOPHOL Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from 5-HYDROXYTRYPTOPHOL manufacturers
- Product
- 5-Hydroxytryptophol 154-02-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000KG
- Release date
- 2024-07-16
- Product
- 5-HYDROXYTRYPTOPHOL 154-02-9
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 95%-99%
- Supply Ability
- 1kg; 100kg； 500kg
- Release date
- 2019-12-24