2-Fluoro-5-nitrotoluene
Application- Product Name
- 2-Fluoro-5-nitrotoluene
- CAS No.
- 455-88-9
- Chemical Name
- 2-Fluoro-5-nitrotoluene
- Synonyms
- 1-FLUORO-2-METHYL-4-NITROBENZENE;5-Nitro-2-fluorotoluene;2-Fluoro-5-nitrotoluene,97%;Benzene, 1-fluoro-2-methyl-4-nitro-;uoro-5-nitrotoL;Fluoronitrotoluene;Fluoronitrotoluene2;2-Fluor-5-nitrotoluol;2-Fluoro-5-nitrotluene;2-FLUORO-5-NITROTOLUENE
- CBNumber
- CB0775579
- Molecular Formula
- C7H6FNO2
- Formula Weight
- 155.13
- MOL File
- 455-88-9.mol
2-Fluoro-5-nitrotoluene Property
- Melting point:
- 38-40 °C (lit.)
- Boiling point:
- 99-100 °C/13 mmHg (lit.)
- Density
- 1.3021 (estimate)
- Flash point:
- 221 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to lump
- color
- White to Light yellow to Green
- BRN
- 1940341
- InChI
- InChI=1S/C7H6FNO2/c1-5-4-6(9(10)11)2-3-7(5)8/h2-4H,1H3
- InChIKey
- XUCYJGMIICONES-UHFFFAOYSA-N
- SMILES
- C1(F)=CC=C([N+]([O-])=O)C=C1C
- CAS DataBase Reference
- 455-88-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, 1-fluoro-2-methyl-4-nitro-(455-88-9)
- EPA Substance Registry System
- Benzene, 1-fluoro-2-methyl-4-nitro- (455-88-9)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36-36/37/39-22
- RIDADR
- UN2811
- WGK Germany
- 3
- Hazard Note
- Irritant
- TSCA
- T
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29049090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F12006
- Product name
- 2-Fluoro-5-nitrotoluene
- Purity
- 99%
- Packaging
- 10g
- Price
- $20.42
- Updated
- 2025/07/31
- Product number
- F0276
- Product name
- 2-Fluoro-5-nitrotoluene
- Purity
- >97.0%(GC)
- Packaging
- 10g
- Price
- $21
- Updated
- 2025/07/31
- Product number
- F0276
- Product name
- 2-Fluoro-5-nitrotoluene
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $27
- Updated
- 2025/07/31
- Product number
- 409768
- Product name
- 1-Fluoro-2-methyl-4-nitrobenzene
- Packaging
- 500mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- F597098
- Product name
- 1-Fluoro-2-methyl-4-nitrobenzene
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
2-Fluoro-5-nitrotoluene Chemical Properties,Usage,Production
Application
2-Fluoro-5-nitrotoluene can be used as a nonlinear optical material in optical devices for applications such as frequency doubling, optical modulation, and optical detection.
Chemical Properties
white to light yellow crystal powder
Synthesis Reference(s)
The Journal of Organic Chemistry, 63, p. 8448, 1998 DOI: 10.1021/jo981557o
Synthesis
13290-74-9
455-88-9
General procedure for the synthesis of 2-fluoro-5-nitrotoluene from 2-chloro-5-nitrotoluene: To an oven-dried resealable reaction tube fitted with a stirrer were added aryl halide (20, 0.12 mmol), BrettPhos (6.4 mg, 0.012 mmol, 10 mol%), (COD)Pd(CH2TMS)2 (2.3 mg. 0.006 mmol, 5 mol%), AgF (23 mg, 0.18 mmol) and toluene (2 mL). The reaction tube was then sealed with a screw cap and removed from the glove box, wrapped in aluminum foil and placed in an oil bath preheated to the indicated temperature with thorough stirring. After 12 hours of reaction, the reaction tube was removed from the oil bath and cooled to room temperature. 4-Fluorotoluene (13.2 μL, 0.12 mmol, 1 eq.) and dodecane (27.3 μL, 0.12 mmol, 1 eq.) were added as internal standards. The reaction mixture was filtered through a glass filter fitted with Celite to remove all solids. Finally, the product yield was analyzed by 19F NMR (282 MHz) and the conversion was determined by GC.
References
[1] Patent: US2011/15401, 2011, A1. Location in patent: Page/Page column 17
[2] Journal of the American Chemical Society, 1959, vol. 81, p. 315,316
2-Fluoro-5-nitrotoluene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Fluoro-5-nitrotoluene manufacturers
- Product
- 2-Fluoro-5-nitrotoluene 455-88-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-01
- Product
- 2-Fluoro-5-nitrotoluene 455-88-9
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-29
- Product
- 2-Fluoro-5-nitrotoluene 455-88-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 20 tons
- Release date
- 2023-09-08