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4-Aminophenylacetonitrile

Product Name
4-Aminophenylacetonitrile
CAS No.
3544-25-0
Chemical Name
4-Aminophenylacetonitrile
Synonyms
4-AMINOBENZYL CYANIDE;2-(4-AMINOPHENYL)ACETONITRILE;AKOS 220-20;TIMTEC-BB SBB004218;4-AMinophenylacetoni;P-AMINOBENZYL CYANIDE;4-(Cyanomethyl)aniline;aminophenylacetonitrile;Paraphenyl acetonitrile;p-aminophenacetonitrile
CBNumber
CB0778671
Molecular Formula
C8H8N2
Formula Weight
132.16
MOL File
3544-25-0.mol
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4-Aminophenylacetonitrile Property

Melting point:
45-48 °C(lit.)
Boiling point:
312 °C(lit.)
Density 
1.4747 (rough estimate)
refractive index 
1.6231 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
pka
4.25±0.10(Predicted)
form 
Crystalline Powder, Crystals or Chunks
color 
Yellow to brown
Water Solubility 
SLIGHTLY SOLUBLE
BRN 
1100108
Exposure limits
NIOSH: IDLH 25 mg/m3
InChIKey
YCWRFIYBUQBHJI-UHFFFAOYSA-N
CAS DataBase Reference
3544-25-0(CAS DataBase Reference)
NIST Chemistry Reference
4-Aminophenylacetic acid nitrile(3544-25-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
36-36/37
RIDADR 
3276
WGK Germany 
3
Hazard Note 
Harmful
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A42050
Product name
4-Aminobenzyl cyanide
Purity
99%
Packaging
10g
Price
$137
Updated
2025/07/31
TCI Chemical
Product number
A1612
Product name
4-Aminobenzyl Cyanide
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$51
Updated
2025/07/31
TCI Chemical
Product number
A1612
Product name
4-Aminobenzyl Cyanide
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$151
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
CHM0025217
Product name
4-AMINO BENZYL CYANIDE
Purity
95.00%
Packaging
2.5G
Price
$852.21
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0025217
Product name
4-AMINO BENZYL CYANIDE
Purity
95.00%
Packaging
1G
Price
$127.05
Updated
2021/12/16
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4-Aminophenylacetonitrile Chemical Properties,Usage,Production

Chemical Properties

yellow to brown crystalline powder, crystals

Uses

4-Aminobenzyl Cyanide can be used to prevent or treat influenza.

Synthesis Reference(s)

Synthetic Communications, 22, p. 3189, 1992 DOI: 10.1080/00397919208021132

Synthesis

P-Nitrophenylacetonitrile (10 g, 61.67 mmol) was dissolved in methanol (50 mL). Add 10 per cent Pd/C (1.0g), Replace the reaction system four times with H2, and Stir at room temperature overnight in an H2 environment (0.5 MPa).TLC analysis, the reaction was complete, and the reaction solution was filtered through celite. The filtrate was concentrated under reduced pressure to give 8.08g of 4-Aminophenylacetonitrile; the yield was 99.1 per cent.

References

[1] Tetrahedron Letters, 1984, vol. 25, # 45, p. 5219 - 5222
[2] Tetrahedron Letters, 1984, vol. 25, # 45, p. 5219 - 5222
[3] Organometallics, 2017, vol. 36, # 16, p. 3110 - 3116
[4] Applied Organometallic Chemistry, 2018, vol. 32, # 1,
[5] Tetrahedron Letters, 2001, vol. 42, # 12, p. 2285 - 2288

4-Aminophenylacetonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Aminophenylacetonitrile Suppliers

Alfa Aesar, Thermo Fisher Scientific
Tel
--
Fax
--
Email
es@alfa.com
Country
Germany
ProdList
5123
Advantage
58
CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
ChemPur GmbH
Tel
--
Fax
--
Email
info@ChemPur.de
Country
Germany
ProdList
2737
Advantage
50
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
AKos Consulting & Solutions GmbH
Tel
--
Fax
--
Email
akos@akosgmbh.de
Country
Germany
ProdList
6717
Advantage
72
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View Lastest Price from 4-Aminophenylacetonitrile manufacturers

Beijing CosmicKoda Chemical Technology Co.,Ltd
Product
4-Aminophenylacetonitrile;P-aminophenylacetonitrile;2-(4-aminophenyl)acetonitrile 3544-25-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
bulk production
Release date
2025-11-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Aminophenylacetonitrile 3544-25-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-10
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Aminophenylacetonitrile 3544-25-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30

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