Fucoxanthin

ChemicalBook > CAS DataBase List > Fucoxanthin

Product Name: Fucoxanthin
CAS No.: 3351-86-8
Chemical Name: Fucoxanthin
Synonyms: Ccris 4055;Brn 0073179;Fucoxanthol;FUCOXANTHIN;Fuconxanthin(P);Fucoxanthin(AS);Fucoxanthin (10%);Fucoxanthin solution;all-trans-Fucoxanthin;(3S,3'S,5R,5'R,6S,6'R)-
CBNumber: CB0780168
Molecular Formula: C42H58O6
Formula Weight: 658.91
MOL File: 3351-86-8.mol

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Fucoxanthin Property

Melting point:: 166-168°C
alpha: D18 +72.5 ±9° (chloroform)
Boiling point:: 590.43°C (rough estimate)
Density: 1.09
refractive index: n20/D1.360-1.362
Flash point:: 14℃
storage temp.: -20°C
solubility: Ethanol,
pka: 14.47±0.60(Predicted)
form: Solid
color: Crystalline
optical activity: +72.518 (CHCl3)
λmax: λ: 444-454 nm Amax
InChIKey: SJWWTRQNNRNTPU-WEAAWPSVSA-N
SMILES: [C@]12(CC(=O)/C(/C)=C/C=C/C(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C=C3[C@@](O)(C)C[C@@H](OC(=O)C)CC3(C)C)C(C)(C)C[C@H](O)C[C@]1(O2)C |&1:0,25,29,42,45,r|
LogP: 7.830 (est)
CAS DataBase Reference: 3351-86-8(CAS DataBase Reference)

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Safety

Hazard Codes: F
Risk Statements: 11
Safety Statements: 7-16-24/25
RIDADR: UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany: 3
HS Code: 29153900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 16337
Product name: Fucoxanthin
Purity: analytical standard
Packaging: 1mg
Price: $95.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 16337
Product name: Fucoxanthin
Purity: analytical standard
Packaging: 5mg
Price: $258
Updated: 2024/03/01

Cayman Chemical

Product number: 13068
Product name: Fucoxanthin
Purity: ≥95%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 13068
Product name: Fucoxanthin
Purity: ≥95%
Packaging: 10mg
Price: $152
Updated: 2024/03/01

Sigma-Aldrich

Product number: F6932
Product name: Fucoxanthin
Purity: carotenoid antioxidant
Packaging: 10mg
Price: $211
Updated: 2024/03/01

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Fucoxanthin Chemical Properties,Usage,Production

Description

Fucoxanthin is another important xanthophyll. It is widely found in heterokontophyta, such as brown algae and oceanic microalgae,and is believed be the second-most abundant carotenoid on Earth after β-carotene. Recently, studies on the functionality of fucoxanthin have been increasingly conducted,and fucoxanthin has been shown to possess various beneficial physiological activities.It has various pharmaceutical effects such as anti-tumor, anti-inflammatory, anti-oxidant, anti-obesity effects, protecting nerve cell, increasing the content of ARA(arachidonic acid) and DHA (docosahexaenoic acid) in mice; It is widely used as medicine, skin care and beauty industry, and in the Food supplements market.

Chemical Properties

Fucoxanthin is an orange-colored pigment, along with chlorophylls a and c and β-carotene, present in Chromophyta (Heterokontophyta or Ochrophyta), including brown seaweeds (Phaeophyceae) and diatoms (Bacillariophyta). It is insoluble in water but soluble in organic solvents such as ethanol; it is typically lipid-soluble powder or oil.

Occurrence

Fucoxanthin is a xanthophyll carotenoid abundant in macroalgae, such as brown seaweeds and microalgae. Several edible brown algae, including Sargassam fusiforme, Laminaria japonica, Undaria pinnatifida, and Padina tetrastromatica, are consumed in Southeast Asia and Europe. The brown algae are good sources of fucoxanthin. However, diatoms, such as Phaeodactylum tricornutum, are preferred sources of fucoxanthin in the food industry because of their higher fucoxanthin content and extraction efficiency with shorter growth cycles than those of macroalgae[1].

Uses

Fucoxanthin is a carotenoid pigment found in fresh brown algae.It can be used as an anti-obesity, anticancer, anti-cholesterol, and anti-diabetic agent and as a food colorant, but it is very unstable. It is easily affected by heating, aerial exposure, and illumination.

Uses

Fucoxanthin is a carotenoid that occurs naturally in certain algae. It significantly reduces abdominal white adipose tissue (WAT) in mice and rats when included in their diet. Fucoxanthin increases the amount of mitochondrial uncoupling protein 1 (UCP1), a fatty acid-stimulated protein involved in respiration and thermogenesis in WAT of mice and rats. In KK-Ay mice, which are used to model obese type 2 diabetics with hyperinsulinemia, fucoxanthin reduces WAT gain and also decreases blood glucose and plasma insulin levels.

Uses

Fucoxanthin has been used to study its neuroprotective effects. It has also been used in calibration to identify the most efficient fucoxanthin producing strains of microalgae.

Definition

ChEBI: A natural product found in Sporochnus comosus.

General Description

Fucoxanthin is isolated from brown algae. It has anti-angiogenic, hepatoprotective,?cardiovascular and cerebrovascular protective properties. Fucoxanthin stimulates G1 cell-cycle arrest and apoptosis in cancer cell lines.

Biochem/physiol Actions

Xanthophyll carotenoid pigment extracted from algae. Exhibits anticancer, antioxidant, anti-obesity and anti-inflammatory properties.

Side effects

There are some potential dangers associated with taking Fucoxanthin. These include an increased risk of bleeding, liver damage, and allergic reactions. Additionally, it may interact with certain medications, such as blood thinners, and can cause side effects such as nausea, vomiting, and diarrhea.

Metabolism

Fucoxanthin is unstable and can be easily degraded by heating, aerial exposure, or illumination. The primary metabolites of fucoxanthin are fucoxanthinol and amarouciaxanthin A. Fucoxanthin can be hydrolyzed to fucoxanthinol in the gastrointestinal tract and further converted into amarouciaxanthin A in the liver. In animal studies, no toxicity of fucoxanthin was observed [1].

References

[1] Minkyung Bae . “Health benefits of fucoxanthin in the prevention of chronic diseases.” Biochimica et biophysica acta. Molecular and cell biology of lipids 1865 11 (2020): Article 158618.

Fucoxanthin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Fucoxanthin manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Fucoxanthin; Kelp extract 3351-86-8
Price: US $0.00/G
Min. Order: 1G
Purity: ≥98% HPLC
Supply Ability: 1000KG
Release date: 2022-09-28

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Fucoxanthin 3351-86-8
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-12-06

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Fucoxanthin 3351-86-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 10%min
Supply Ability: 30tons/month
Release date: 2023-01-14

3351-86-8, FucoxanthinRelated Search:

Astaxanthin Punicalagin Sodium alginate Corosolic acid PROPOLIS EXTRACT FROM PENNSYLVANIA BETA-GLUCAN CHLOROPHYLL CAROTENOID MIXED STANDARD 500UL(SH) β-Carotene Carotene 3-METHYL-1,2-BUTADIENE Fucoxanthin 1,2-PENTADIENE hepta-1,2-diene 3,5,7-Nonatrien-2-one HEXA-4,5-DIEN-1-OL ACETIC ACID CIS-3,3,5-TRIMETHYLCYCLOHEXYL ESTER 2,3-PENTADIENE

Fucoxanthin, froM LaMinariajaponicaAresch

Fucoxanthin solution

6'R,7'-didehydro-5R,6-epoxy-4',5',6S,7-tetrahydro-3S,3'S,5'R-trihydroxy-β,β-caroten-8(5H)-one

Fucoxanthin, 98%, from Laminaria japonica Aresch

(3S,3'S,5R,5'R,6S,6'R)-6',7'-Didehydro-5,6-epoxy-4',5',6,7-tetrahydro-3,3',5'-trihydroxy-,-caroten-8(5H)-one

all-trans-Fucoxanthin

Fucoxanthin DISCONTINUED

(3S,3'S,5R,5'R,6S,6'R)-

Fucoxanthol

beta,beta-Carotene, 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-, (3S,3'S,5R,5'R,6S,6'R)-

Brn 0073179

Ccris 4055

FUCOXANTHIN, CAROTENOID ANTIOXIDANT

(3S,3'S,5R,5'R,6S,6'R,8'R)-3,5,5',6-Tetrahydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-β,β-caroten-3'-yl acetate

(3s,3’s,5r,5’r,6s,6’r)-hydro-5’-dihydroxy-8-oxo-

beta,beta-carotene,3’-(acetyloxy)-6’,7’-didehydro-5,6-epoxy-5,5’,6,6’,7,8-hexa

3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-beta,beta-carotene

FUCOXANTHIN

β,β-Carotene, 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-, (3S,3'S,5R,5'R,6S,6'R)-

Fucoxanthin (10%)

Fuconxanthin(P)

β,β-Carotene, 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-, (3S,3'S,5R,5'R,6S,6'R)-

(1S,3R)-3-Hydroxy-4-((R,3E,5E,7E,9E,11E,13E,15E)-18-((1S,4S,6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)-3,7,12,16-tetramethyl-17-oxooctadeca-1,3,5,7,9,11,13,15-octaen-1-ylidene)-3,5,5-trimethylcyclohexyl acetate

Fucoxanthin(AS)

3351-86-8

C42H60O7

C40H60O6

C42H58O6

Herb extract

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Intermediates & Fine Chemicals

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