2-AMINO-5-BROMO-6-METHYLPYRAZINE
- Product Name
- 2-AMINO-5-BROMO-6-METHYLPYRAZINE
- CAS No.
- 74290-69-0
- Chemical Name
- 2-AMINO-5-BROMO-6-METHYLPYRAZINE
- Synonyms
- 5-Bromo-6-methyl-2-pyrazinamine;5-bromo-6-methylpyrazin-2-amine;2-AMINO-5-BROMO-6-METHYLPYRAZINE;2-Pyrazinamine, 5-bromo-6-methyl-;5-BROMO-6-METHYLPYRAZIN-2-YLAMINE;2-AMINO-5-BROMO-6-METHYLPYRAZINE ISO 9001：2015 REACH
- CBNumber
- CB0839352
- Molecular Formula
- C5H6BrN3
- Formula Weight
- 188.03
- MOL File
- 74290-69-0.mol
2-AMINO-5-BROMO-6-METHYLPYRAZINE Property
- Boiling point:
- 273.8±35.0 °C(Predicted)
- Density
- 1.699±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 1.96±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A594600
- Product name
- 2-Amino-5-bromo-6-methylpyrazine
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3H30-9-2R
- Product name
- 2-Amino-5-bromo-6-methylpyrazine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $296
- Updated
- 2021/12/16
- Product number
- FB143944
- Product name
- 5-Bromo-6-methylpyrazin-2-amine
- Packaging
- 500mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- 076260
- Product name
- 2-Amino-5-bromo-6-methylpyrazine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $416
- Updated
- 2021/12/16
- Product number
- W8204
- Product name
- 2-Amino-5-bromo-6-methylpyrazine
- Packaging
- 250mg
- Price
- $146
- Updated
- 2021/12/16
2-AMINO-5-BROMO-6-METHYLPYRAZINE Chemical Properties,Usage,Production
Synthesis
5521-56-2
74290-69-0
General procedure for the synthesis of 2-amino-5-bromo-6-methylpyrazine from 2-amino-6-methylpyrazine: 6-amino-2-methylpyrazine (100 mg, 1.0 eq.) was dissolved in a solvent mixture of DMSO (4.6 mL) and water (0.2 mL) under an inert atmosphere and cooled in an ice bath. To this solution was added N-bromosuccinimide (NBS, 179 mg, 1.1 eq.) in three portions. The reaction mixture was light yellow in color and stirred for 15 minutes, then the ice bath was removed and stirring was continued for 5 hours at room temperature. After completion of the reaction, the reaction was quenched with saturated NaHCO3 solution (25 mL) and extracted with ethyl acetate (EtOAc, 30 mL). The organic layer was washed with brine, dried over anhydrous Na2SO4 and concentrated under reduced pressure. Purification by fast column chromatography afforded the target compound 2-amino-5-bromo-6-methylpyrazine (Compound 10) as a light yellow solid in 36% yield.1H-NMR (400 MHz, DMSO-d6): δ 2.34 (s, 3H, CH3), 6.52 (s, 2H, NH2), 7.49 (s, 1H, Ar-H). Mass spectrum (ESI): m/z 188.2 ([M+H]+, 79Br).
References
[1] Patent: EP2666775, 2013, A1. Location in patent: Paragraph 02222
[2] Patent: WO2013/174822, 2013, A1. Location in patent: Page/Page column 86
2-AMINO-5-BROMO-6-METHYLPYRAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-5-BROMO-6-METHYLPYRAZINE manufacturers
- Product
- 2-AMINO-5-BROMO-6-METHYLPYRAZINE 74290-69-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-07
- Product
- 2-AMINO-5-BROMO-6-METHYLPYRAZINE 74290-69-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-14