2-Amino-4-methyl-5-bromopyrimidine

Product Name: 2-Amino-4-methyl-5-bromopyrimidine
CAS No.: 17321-93-6
Chemical Name: 2-Amino-4-methyl-5-bromopyrimidine
Synonyms: 100704;5-Bromo-4-methyl-2-pyrimidinamine;2-PyriMidinaMine,5-broMo-4-Methyl-;2-Amino-5-bromo-4-methylpyrimidine;2-amino-4-methyl-5-bromopyrimidine;5-Bromo-4-methyl-2-aminopyrimidine;5-Bromo-2-amino-4-methylpyrimidine;5-bromo-4-methylpyrimidine-2-ylamine;5-BROMO-4-METHYL-PYRIMIDIN-2-YLAMINE;2-AMino-5-broMo-4-MethylpyriMidine 97%
CBNumber: CB01010770
Molecular Formula: C5H6BrN3
Formula Weight: 188.03
MOL File: 17321-93-6.mol

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2-Amino-4-methyl-5-bromopyrimidine Property

Melting point:: 192-194℃
Boiling point:: 345.4±34.0 °C(Predicted)
Density: 1.699±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
pka: 2.47±0.10(Predicted)
Appearance: White to light yellow Solid
InChI: InChI=1S/C5H6BrN3/c1-3-4(6)2-8-5(7)9-3/h2H,1H3,(H2,7,8,9)
InChIKey: LPQVTZJEIXYDQA-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Br)C(C)=N1
CAS DataBase Reference: 17321-93-6

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
WGK Germany: 3
TSCA: N
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 715085
Product name: 2-Amino-5-bromo-4-methylpyrimidine
Purity: 97%
Packaging: 1g
Price: $68.8
Updated: 2023/06/20

TRC

Product number: A602188
Product name: 2-Amino-5-bromo-4-methylpyrimidine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: A602188
Product name: 2-Amino-5-bromo-4-methylpyrimidine
Packaging: 500mg
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-9-CW
Product name: 2-Amino-4-methyl-5-bromopyrimidine
Purity: 95%
Packaging: 1g
Price: $16
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA12130
Product name: 2-Amino-4-methyl-5-bromopyrimidine
Packaging: 2g
Price: $189
Updated: 2021/12/16

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2-Amino-4-methyl-5-bromopyrimidine Chemical Properties,Usage,Production

Synthesis

108-52-1

17321-93-6

General procedure for the synthesis of 2-amino-4-methyl-5-bromopyrimidine from 2-amino-4-methylpyrimidine: To a solution of 4-methylpyrimidin-2-ylamine (10.9 g, 100 mmol) in chloroform (400 mL) was added N-bromosuccinimide (17.8 g, 100 mmol). The reaction mixture was stirred under light-avoiding conditions for 15 hours. Upon completion of the reaction, the mixture was transferred to dichloromethane (140 mL) and washed sequentially with 1N sodium hydroxide solution (3 x 200 mL) and saturated sodium chloride solution (100 mL). The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give 5-bromo-4-methylpyrimidin-2-ylamine (18.8 g, 99% yield). The product was detected by LCMS (m/z): 188.0/190.0 (MH+). 1H NMR (CDCl3) data: δ 8.22 (s, 1H), 5.02 (bs, 2H), 2.44 (s, 3H).

References

[1] Patent: WO2007/84786, 2007, A1. Location in patent: Page/Page column 91-92
[2] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 10, p. 774 - 779
[3] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 180
[4] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0377; 0378
[5] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0330

2-Amino-4-methyl-5-bromopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-4-methyl-5-bromopyrimidine Suppliers

China 126 India 2 United Kingdom 3 United States 14 Global 145

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J & K SCIENTIFIC LTD.

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View Lastest Price from 2-Amino-4-methyl-5-bromopyrimidine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 2-Amino-4-methyl-5-bromopyrimidine 17321-93-6
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-12

Jiangsu Liyang Kunlun Biological Technology Co., Ltd.

Product: 5-Bromo-4-methyl-pyrimidin-2-ylamine 17321-93-6
Price: US $0.00-0.00/kg
Min. Order: 50kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2025-03-11

Shanghai Rlavie Technology Co ltd

Product: 2-Amino-5-bromo-4-methylpyrimidine 17321-93-6
Price: US $0.00-0.00/kg
Min. Order: 0.0001kg
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-05-10

17321-93-6, 2-Amino-4-methyl-5-bromopyrimidineRelated Search:

5-Bromopyrimidine 2-Pyrimidinamine, 4-bromo- (9CI) 2-Aminopyrimidine N,N-Dimethyl-1,4-phenylenediamine Pirimiphos-methyl 2-Amino-5-bromopyrimidine 5-Amino-2-methylpyridine METSULFURON METHYL Kresoxim-methyl Methyl acetate Amino tris(methylene phosphonic acid) Methyl salicylate Methylparaben Bensulfuron methyl Thiophanate-methyl Tris(hydroxymethyl)aminomethane Methyl Methyl bromide

5-BROMO-4-METHYL-PYRIMIDIN-2-YLAMINE

5-Bromo-4-methyl-2-aminopyrimidine

2-amino-4-methyl-5-bromopyrimidine

2-Amino-5-bromo-4-methylpyrimidine

2-PyriMidinaMine,5-broMo-4-Methyl-

2-AMino-5-broMo-4-MethylpyriMidine

2-AMino-5-broMo-4-MethylpyriMidine 97%

100704

5-bromo-4-methylpyrimidine-2-ylamine

2-Amino-4-methyl-5-bromopyrimidine ISO 9001：2015 REACH

5-Bromo-4-methyl-2-pyrimidinamine

5-Bromo-2-amino-4-methylpyrimidine

17321-93-6

Heterocycle-Pyrimidine series