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sodium acetrizoate

Product Name
sodium acetrizoate
CAS No.
129-63-5
Chemical Name
sodium acetrizoate
Synonyms
Acidum;MP1023;Reopak;MP 1023;MP-1023;Diaginol;Acetrizoato sodico;Acetrizoate sodium;sodium acetrizoate;Acetrizoate de sodium
CBNumber
CB0874920
Molecular Formula
C9H7I3NNaO3
Formula Weight
580.86
MOL File
129-63-5.mol
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sodium acetrizoate Property

EPA Substance Registry System
Benzoic acid, 3-(acetamido)-2,4,6-triiodo-, monosodium salt (129-63-5)
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Safety

Toxicity
LD50 in rabbits, cats, dogs (mg/kg): 5200, 5600, 6300 i.v. (Hoppe)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S403873
Product name
3-ACETAMIDO-2,4,6-TRIIODOBENZOIC ACID, SODIUM SALT DIHYDRATE
Purity
Aldrich
Packaging
50mg
Price
$179
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
DYE0000524
Product name
ACETRIZOATE SODIUM
Purity
95.00%
Packaging
5MG
Price
$501.07
Updated
2021/12/16
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sodium acetrizoate Chemical Properties,Usage,Production

Originator

Urokon Sodium ,Mallinckrodt Inc. ,US ,1950

Manufacturing Process

3-Amino-2,4,6-triiodobenzoic acid (51.5 g) was mixed with 125 ml of acetic anhydride containing 2 drops of concentrated sulfuric acid and refluxed for thirty minutes. The mixture was allowed to cool slightly, and then was poured into 600 ml of water at room temperature and stirred until crystallization was complete. The mixed anhydride of 3-acetylamino-2,4,6-triiodobenzoic acid with acetic acid thus prepared was then separated by filtration and washed with water. Without drying, the solid was suspended in 600 ml of water and hydrolyzed with a slight excess of ammonium hydroxide. It was necessary to warm the mixture slightly and stir it for about one-half hour in order to dissolve all the solid. The solution was then treated with activated carbon, filtered and precipitated with an excess of hydrochloric acid, filtered, washed and dried at 70°C. The yield was 51.5 g of 3-acetylamino-2,4,6-triiodobenzoic acid which melted at 276.6-278.2°C with decomposition when placed in the melting block at 260°C and heated at the rate of 3°C per minute. Due to decomposition, the melting point varied from about 269-280°C, depending upon the rate of heating and other conditions.
3-Acetylamino-2,4,6-triiodobenzoic acid (28 g) was dissolved in a little over 50 ml of 1 N sodium hydroxide in a round-bottom flask. The pH was adjusted to slightly over 7 and the solution was evaporated on a steam bath under reduced pressure. After the residue became solid, it was further dried overnight in a vacuum desiccator containing calcium chloride. The salt weighed 31.2 g, theory being 29.0 g, indicating that the product contains about 7% water of crystallization when dried under these conditions. The finished salt was scraped from the flask and ground.

brand name

Salpix (Ortho-McNeil).

Therapeutic Function

Diagnostic aid (radiopaque medium)

Safety Profile

Mildly toxic by intravenous route.When heated to decomposition it emits very toxic fumes ofNOx, Na2O, and HI.

sodium acetrizoate Preparation Products And Raw materials

Raw materials

Preparation Products

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sodium acetrizoate Suppliers

Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
23325
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30241
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8617
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
15229059051
Email
1027@dideu.com
Country
China
ProdList
9982
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38463
Advantage
58
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View Lastest Price from sodium acetrizoate manufacturers

Dideu Industries Group Limited
Product
SodiumAcetrizoate
Price
US $1.10/g
Min. Order
1g
Purity
0.999
Supply Ability
100 Tons min
Release date
2021-08-13

129-63-5, sodium acetrizoateRelated Search:


  • sodium 3-acetamido-2,4,6-triiodobenzoate
  • sodium acetrizoate
  • Acidum
  • 2,4,6-Trijod-3-acetaminobenzosaeure natrium
  • 2,4,6-Trijod-3-acetaminobenzosaeure natrium [german]
  • 3-Acetamido-2,4,6-triiodobenzoic acid sodium salt
  • Acetrizoate de sodium
  • Acetrizoate de sodium [inn-french]
  • Acetrizoate sodium
  • Acetrizoato sodico
  • Acetrizoato sodico [dcit]
  • Acetrizoic acid sodium salt
  • 3-ACETAMIDO-2,4,6-TRIIODOBENZOIC ACID, SODIUM SALT DIHYDRATE
  • SodiumAcetrizoate USP/EP/BP
  • Diaginol
  • MP 1023
  • MP1023
  • MP-1023
  • Reopak
  • 129-63-5
  • C9H5I3NNaO3