Letosteine
- Product Name
- Letosteine
- CAS No.
- 53943-88-7
- Chemical Name
- Letosteine
- Synonyms
- Visoctiol;Viscotiol;Letosteine;2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid;2-[2-[(2-Ethoxy-2-oxoethyl)thio]ethyl]-4-thiazolidinecarboxylic acid;4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-;2-[2-(2-Ethoxy-2-oxoethyl)sulfanylethyl]-1,3-thiazolidine-4-carboxylic acid
- CBNumber
- CB0875396
- Molecular Formula
- C10H17NO4S2
- Formula Weight
- 279.38
- MOL File
- 53943-88-7.mol
Letosteine Property
- Melting point:
- 142°
- Boiling point:
- 470.0±45.0 °C(Predicted)
- Density
- 1.284±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Dichloromethane (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 2.05±0.40(Predicted)
- color
- White to Pale Yellow
- CAS DataBase Reference
- 53943-88-7
N-Bromosuccinimide Price
- Product number
- L330103
- Product name
- Letosteine
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- L330103
- Product name
- Letosteine
- Packaging
- 1g
- Price
- $220
- Updated
- 2021/12/16
- Product number
- API0010497
- Product name
- 2-[2-(2-ETHOXY-2-OXOETHYL)SULFANYLETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $240.45
- Updated
- 2021/12/16
- Product number
- J11158
- Product name
- Letosteine
- Packaging
- 100mg
- Price
- $298
- Updated
- 2021/12/16
- Product number
- J11158
- Product name
- Letosteine
- Packaging
- 5mg
- Price
- $49
- Updated
- 2021/12/16
Letosteine Chemical Properties,Usage,Production
Originator
Viscotiol,Carlo Erba,France,1979
Definition
ChEBI: A dicarboxylic acid monoester that is the monoethyl ester of 2-{2-[(carboxymethyl)sulfanyl]ethyl}-1,3-thiazolidine-4-carboxylic acid. A mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
Manufacturing Process
In an Erlenmeyer flask placed in an ice bath, and under a well-ventilated
hood, a solution of 0.1 mol of acrolein in 100 ml of ether was introduced, With
the aid of a bromine ampoule, 0.1 mol (= 11 ml) of the ethyl ester of
thioglycolic acid containing 0.5 ml of triethylamine was added drop by drop.
One hour after completion of the addition, there was added 0.1 mol (15.6 g)
of chlorhydrate of cysteine in alcoholic solution. The chlorhydrate of the
expected derivative, which appeared in the form of a thick oil, was
precipitated by addition of 0.1 mol (10 g) of potassium acetate in aqueous
solution. The abundant precipitate obtained was filtered and washed in water
and ether. The product was recrystallized in a minimum of absolute alcohol.
Therapeutic Function
Mucolytic
Letosteine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Letosteine manufacturers
- Product
- Letosteine 53943-88-7
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg, 5kg ,50kg
- Release date
- 2020-01-08