ChemicalBook > CAS DataBase List > Letosteine

Letosteine

Product Name
Letosteine
CAS No.
53943-88-7
Chemical Name
Letosteine
Synonyms
Visoctiol;Viscotiol;Letosteine;2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid;2-[2-[(2-Ethoxy-2-oxoethyl)thio]ethyl]-4-thiazolidinecarboxylic acid;4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-;2-[2-(2-Ethoxy-2-oxoethyl)sulfanylethyl]-1,3-thiazolidine-4-carboxylic acid
CBNumber
CB0875396
Molecular Formula
C10H17NO4S2
Formula Weight
279.38
MOL File
53943-88-7.mol
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Letosteine Property

Melting point:
142°
Boiling point:
470.0±45.0 °C(Predicted)
Density 
1.284±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Dichloromethane (Slightly), DMSO (Slightly)
form 
Solid
pka
2.05±0.40(Predicted)
color 
White to Pale Yellow
CAS DataBase Reference
53943-88-7
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
L330103
Product name
Letosteine
Packaging
100mg
Price
$50
Updated
2021/12/16
TRC
Product number
L330103
Product name
Letosteine
Packaging
1g
Price
$220
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010497
Product name
2-[2-(2-ETHOXY-2-OXOETHYL)SULFANYLETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID
Purity
95.00%
Packaging
1G
Price
$240.45
Updated
2021/12/16
AK Scientific
Product number
J11158
Product name
Letosteine
Packaging
100mg
Price
$298
Updated
2021/12/16
AK Scientific
Product number
J11158
Product name
Letosteine
Packaging
5mg
Price
$49
Updated
2021/12/16
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Letosteine Chemical Properties,Usage,Production

Originator

Viscotiol,Carlo Erba,France,1979

Definition

ChEBI: A dicarboxylic acid monoester that is the monoethyl ester of 2-{2-[(carboxymethyl)sulfanyl]ethyl}-1,3-thiazolidine-4-carboxylic acid. A mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.

Manufacturing Process

In an Erlenmeyer flask placed in an ice bath, and under a well-ventilated hood, a solution of 0.1 mol of acrolein in 100 ml of ether was introduced, With the aid of a bromine ampoule, 0.1 mol (= 11 ml) of the ethyl ester of thioglycolic acid containing 0.5 ml of triethylamine was added drop by drop.
One hour after completion of the addition, there was added 0.1 mol (15.6 g) of chlorhydrate of cysteine in alcoholic solution. The chlorhydrate of the expected derivative, which appeared in the form of a thick oil, was precipitated by addition of 0.1 mol (10 g) of potassium acetate in aqueous solution. The abundant precipitate obtained was filtered and washed in water and ether. The product was recrystallized in a minimum of absolute alcohol.

Therapeutic Function

Mucolytic

Letosteine Preparation Products And Raw materials

Raw materials

Preparation Products

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Letosteine Suppliers

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View Lastest Price from Letosteine manufacturers

Career Henan Chemical Co
Product
Letosteine 53943-88-7
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg, 5kg ,50kg
Release date
2020-01-08

53943-88-7, LetosteineRelated Search:


  • 2-[2-(2-Ethoxy-2-oxoethyl)sulfanylethyl]-1,3-thiazolidine-4-carboxylic acid
  • 4-Thiazolidinecarboxylic acid, 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-
  • Viscotiol
  • Visoctiol
  • 2-[2-[(2-Ethoxy-2-oxoethyl)thio]ethyl]-4-thiazolidinecarboxylic acid
  • Letosteine
  • 2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)thiazolidine-4-carboxylic acid
  • 53943-88-7
  • C10H17NO4S2
  • API