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viloxazine

Product Name
viloxazine
CAS No.
46817-91-8
Chemical Name
viloxazine
Synonyms
viloxazine;2-[(2-Ethoxyphenoxy)methyl]morpholine;Morpholine, 2-[(2-ethoxyphenoxy)methyl]-;Metrifonate Impurity 2-d6(Metrifonate EP Impurity B-d6)(Dichlorvos-d6)
CBNumber
CB0911793
Molecular Formula
C13H19NO3
Formula Weight
237.29
MOL File
46817-91-8.mol
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viloxazine Property

Melting point:
176-179 °C
Boiling point:
379.83°C (rough estimate)
Density 
1.0942 (rough estimate)
refractive index 
1.5000 (estimate)
pka
pKa 8.1 (Uncertain)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
AS233199
Product name
2-((2-Ethoxyphenoxy)methyl)morpholine
Purity
99%
Packaging
1g
Price
$937
Updated
2021/12/16
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viloxazine Chemical Properties,Usage,Production

Originator

Vivalan,I.C.I. ,UK,1974

Uses

Antidepressant.

Definition

ChEBI: 2-[(2-ethoxyphenoxy)methyl]morpholine is an aromatic ether.

Manufacturing Process

2-Ethoxyphenol is first reacted with epichlorohydrin to give 1,2-epoxy-3-(o- ethoxyphenoxy)-propane.
A mixture of crude (83%) 1,2-epoxy-3-(o-ethoxyphenoxy)propane (19.4 grams), 70.5 grams 2-aminoethyl hydrogen sulfate, 40.0 grams sodium hydroxide, 400 ml ethanol and 200 ml water is stirred at 60°C for 18 hours and is then evaporated to dryness. The residue is dissolved in 200 ml water and the mixture is extracted three times with 150 ml of diethyl ether each time. The combined extracts are dried over magnesium sulfate and evaporated to dryness, The crude product (21.5 grams) is dissolved in isopropanol (20 ml), 10.5 ml concentrated aqueous hydrochloric acid and 75 ml ethyl acetate are added and the mixture is cooled. The mixture is filtered and there is thus obtained as solid product 2-(o-ethoxyphenoxymethyl) morpholine hydrochloride, MP 179° to 182°C (8.6 grams; 38% yield based on total epoxide used), according to US Patent 3,712,890.

Therapeutic Function

Psychotropic

viloxazine Preparation Products And Raw materials

Raw materials

Preparation Products

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viloxazine Suppliers

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
15229059051
Email
1027@dideu.com
Country
China
ProdList
10003
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6773
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9639
Advantage
58
Win-Win chemical CO., Limited
Tel
+86-0086-577-64498589 +86-15355981851
Fax
0086-577-56994596
Email
sales@win-winchemical.com
Country
China
ProdList
14427
Advantage
58
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View Lastest Price from viloxazine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
viloxazine 46817-91-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2024-11-08
Qiuxian Baitai New Material Co., LTD
Product
Viloxazine
Price
US $25.00-500.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
500ton/Month
Release date
2021-09-10