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zipeprol

Product Name
zipeprol
CAS No.
34758-83-3
Chemical Name
zipeprol
Synonyms
zipeprol;Zipeprolum;Unii-G5muv8139h;Einecs 252-191-7;Zipeprol USP/EP/BP;Zipeprolum [inn-latin];34758-84-4 (Di-hydrochloride);α-(α-Methoxybenzyl)-4-(β-methoxyphenethyl)-1-piperazineethanol;1-Piperazineethanol, 4-(2-methoxy-2-phenylethyl)-α-(methoxyphenylmethyl)-;1-methoxy-3-(4-(2-methoxy-2-phenylethyl)piperazin-1-yl)-1-phenylpropan-2-ol
CBNumber
CB0916495
Molecular Formula
C23H32N2O3
Formula Weight
384.52
MOL File
34758-83-3.mol
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zipeprol Property

Melting point:
83°
Boiling point:
507.7±50.0 °C(Predicted)
Density 
1.108±0.06 g/cm3(Predicted)
pka
13.97±0.20(Predicted)
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Safety

DEA Controlled Substances
CSCN: 9873
CSA SCH: Schedule I
NARC: Yes
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Hazard and Precautionary Statements (GHS)

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zipeprol Chemical Properties,Usage,Production

Originator

Respilene,Winthrop,France,1973

Definition

ChEBI: Zipeprol is a benzyl ether.

Manufacturing Process

In a reactor provided with a mechanical stirrer, a reflux refrigerant and a thermometer, there is introduced: 393 grams 1-[2-phenyl, 2-methoxy]ethyl piperazine and 22 grams 3-phenyl-3-methoxy propylene oxide in 750 ml of absolute ethanol.
When the slightly exothermic reaction (rise in temperature of about 20°C) has ceased, heating is effected for 1.5 hours at 60°C. The product is then cooled to 4°C and left to crystallize for about 12 hours. The precipitate is centrifugated then recrystallized in 500 ml of absolute ethanol.
420 grams of the desired compound is thus obtained in the form of a white, crystalline powder, melting point 83°C.

brand name

Antitaxil-z;Antituxil-z;Balutox;Broncozina;Bronx;Cerm-3024;Citizeta;Mirsol;Ogyline;Respilene;Respirase;Respirex;Santus;Talasa;Zitoxil.

Therapeutic Function

Bronchodilator

zipeprol Preparation Products And Raw materials

Raw materials

Preparation Products

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zipeprol Suppliers

34758-83-3, zipeprolRelated Search:


  • zipeprol
  • α-(α-Methoxybenzyl)-4-(β-methoxyphenethyl)-1-piperazineethanol
  • 34758-84-4 (Di-hydrochloride)
  • 4-(2-Methoxy-2-phenylethyl)-alpha-(methoxyphenylmethyl)-1-piperazineethanol
  • Einecs 252-191-7
  • Unii-G5muv8139h
  • Zipeprolum
  • Zipeprolum [inn-latin]
  • 1-methoxy-3-(4-(2-methoxy-2-phenylethyl)piperazin-1-yl)-1-phenylpropan-2-ol
  • 1-Piperazineethanol, 4-(2-methoxy-2-phenylethyl)-α-(methoxyphenylmethyl)-
  • Zipeprol USP/EP/BP
  • 34758-83-3