ChemicalBook > CAS DataBase List > naftazone
naftazone
- Product Name
- naftazone
- CAS No.
- 15687-37-3
- Chemical Name
- naftazone
- Synonyms
- Etioven;C05CX02;Mediaven;naftazone;Karbinone;Naftazone-d6;naftazone USP/EP/BP;15687-37-3 USP/EP/BP;1,2-naphthoquinone semicarbazone;2-[1-Oxonaphthalen-2(1H)-ylidene]hydrazinecarboxamide
- CBNumber
- CB0933874
- Molecular Formula
- C11H9N3O2
- Formula Weight
- 215.21
- MOL File
- 15687-37-3.mol
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naftazone Property
- Density
- 1.40±0.1 g/cm3(Predicted)
- pka
- 12.93±0.20(Predicted)
- form
- Solid
- color
- Yellow to orange
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N-Bromosuccinimide Price
TRC
- Product number
- N359270
- Product name
- 2-(1-Oxo-2(1H)-naphthalenylidene)-hydrazinecarboxamide
- Packaging
- 1g
- Price
- $1455
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0012014
- Product name
- NAFTAZONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.87
- Updated
- 2021/12/16
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naftazone Chemical Properties,Usage,Production
Uses
2-(1-Oxo-2(1H)-naphthalenylidene)-hydrazinecarboxamide is a novel anti-anflammatory agent as well as an anti-proliferative agent due to its 1,2-napthoquinone substructure.
Definition
ChEBI: Naftazone is a member of naphthalenes.
in vivo
Naftazone (10 and 100 mg/kg; p.o. once per day for 15 days) affects glutamate content in cerebro spinal fluid[1]. Naftazone (50 mg/kg; i.p. once per day for 5 days) affects platelet function in rats[2].
| Animal Model: | Male rats[1] |
| Dosage: | 10 and 100 mg/kg |
| Administration: | Oral gavage; 10 and 100 mg/kg once per day; for 15 days |
| Result: | Significantly reduced glutamate content in cerebro spinal fluid of rats. |
| Animal Model: | Wistar rats[2] |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal injection ; 50 mg/kg once daily for 5 days |
| Result: | Reduced the height of platelet aggregation induced by ADP, significantly increased the platelet disaggregation induced by collagen and reduced fibrinogen binding to 2.5 or 5 μM ADP-stimulated platelet. |
naftazone Preparation Products And Raw materials
Raw materials
Preparation Products
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