ChemicalBook > CAS DataBase List > naftazone

naftazone

Product Name
naftazone
CAS No.
15687-37-3
Chemical Name
naftazone
Synonyms
Etioven;C05CX02;Mediaven;naftazone;Karbinone;Naftazone-d6;naftazone USP/EP/BP;15687-37-3 USP/EP/BP;1,2-naphthoquinone semicarbazone;2-[1-Oxonaphthalen-2(1H)-ylidene]hydrazinecarboxamide
CBNumber
CB0933874
Molecular Formula
C11H9N3O2
Formula Weight
215.21
MOL File
15687-37-3.mol
More
Less

naftazone Property

Density 
1.40±0.1 g/cm3(Predicted)
pka
12.93±0.20(Predicted)
form 
Solid
color 
Yellow to orange
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
N359270
Product name
2-(1-Oxo-2(1H)-naphthalenylidene)-hydrazinecarboxamide
Packaging
1g
Price
$1455
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012014
Product name
NAFTAZONE
Purity
95.00%
Packaging
5MG
Price
$498.87
Updated
2021/12/16
More
Less

naftazone Chemical Properties,Usage,Production

Uses

2-(1-Oxo-2(1H)-naphthalenylidene)-hydrazinecarboxamide is a novel anti-anflammatory agent as well as an anti-proliferative agent due to its 1,2-napthoquinone substructure.

Definition

ChEBI: Naftazone is a member of naphthalenes.

in vivo

Naftazone (10 and 100 mg/kg; p.o. once per day for 15 days) affects glutamate content in cerebro spinal fluid[1]. Naftazone (50 mg/kg; i.p. once per day for 5 days) affects platelet function in rats[2].

Animal Model:Male rats[1]
Dosage:10 and 100 mg/kg
Administration:Oral gavage; 10 and 100 mg/kg once per day; for 15 days
Result:Significantly reduced glutamate content in cerebro spinal fluid of rats.
Animal Model:Wistar rats[2]
Dosage:50 mg/kg
Administration:Intraperitoneal injection ; 50 mg/kg once daily for 5 days
Result:Reduced the height of platelet aggregation induced by ADP, significantly increased the platelet disaggregation induced by collagen and reduced fibrinogen binding to 2.5 or 5 μM ADP-stimulated platelet.

naftazone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

naftazone Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
6059
Advantage
65
Shanghai Bank Pharma Limited
Tel
021-2221346380 021-54220652 17701603001
Fax
QQ:2221346380
Email
bankpharma@163.com
Country
China
ProdList
423
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
029-029-81024372 17792795018
Fax
029-88380327
Email
1027@dideu.com
Country
China
ProdList
9997
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6753
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
18003
Advantage
58

15687-37-3, naftazoneRelated Search:


  • naftazone
  • 2-[1-Oxonaphthalen-2(1H)-ylidene]hydrazinecarboxamide
  • Karbinone
  • Mediaven
  • 1,2-naphthoquinone semicarbazone
  • Naftazone-d6
  • Hydrazinecarboxamide, 2-(1-oxo-2(1H)-naphthalenylidene)-
  • naftazone USP/EP/BP
  • 15687-37-3 USP/EP/BP
  • C05CX02
  • Etioven
  • 15687-37-3
  • ACTIVE PHARMACEUTICAL INGREDIENTS