perimetazine

Product Name: perimetazine
CAS No.: 13093-88-4
Chemical Name: perimetazine
Synonyms: RP-9159;RP 9159;Leptryl;AN-1317;AN 1317;perimetazine;1-[3-(2-methoxyphenothiazin-10-yl)-2-methylpropyl]piperidin-4-ol;1-(3-(2-Methoxy-10H-phenothiazin-10-yl)-2-methylpropyl)piperidin-4-ol;4-Piperidinol, 1-[3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]-
CBNumber: CB0936936
Molecular Formula: C22H28N2O2S
Formula Weight: 384.541
MOL File: 13093-88-4.mol

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perimetazine Property

Melting point:: 137-138°
Boiling point:: 569.1±50.0 °C(Predicted)
Density: 1.0944 (rough estimate)
refractive index: 1.6000 (estimate)
pka: 14.87±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P287000
Product name: Perimethazine
Packaging: 250mg
Price: $165
Updated: 2021/12/16

TRC

Product number: P287000
Product name: Perimethazine
Packaging: 2.5g
Price: $1320
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 61034
Product name: Perimethazine
Packaging: 2.5g
Price: $2200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0012224
Product name: PERIMETAZINE
Purity: 95.00%
Packaging: 5MG
Price: $498.87
Updated: 2021/12/16

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perimetazine Chemical Properties,Usage,Production

Originator

Leptryl ,Roger Bellon, France,1970

Uses

Perimethazine, is a novel Antipsychotic drug. It has shown to cause sedation, hypothermia, muscle relaxation, and other signs of central depression in rabbits.

Definition

ChEBI: Perimetazine is a member of phenothiazines.

Manufacturing Process

A solution of 3-methoxy-10-(3-chloro-2-methylpropyl)phenthiazine (9.65 grams) and 4-hydroxypiperidine (6.1 grams) in xylene (10 cc) is heated under reflux for 5 hours. After cooling the mixture is diluted with ether (60 cc) and the basic compounds are extracted by agitation with water (30 cc) and 4 N hydrochloric acid (20 cc). The aqueous acid phase is made alkaline with 4 N sodium hydroxide solution (23 cc) and the liberated base is extracted with ether. The ethereal solution is washed with water (60 cc) and dried over sodium sulfate. Finally the solvent is distilled off on a water-bath.
The solid residue obtained is recrystallized from a mixture (15:85) of benzene and cyclohexane and there is obtained 3-rnethoxy-10-[2-methyl-3-(4hydroxy-1-piperidyl)-propyl]-phenthiazine (5.7 grams) as a white crystalline powder, MP 137°-138°C.

Therapeutic Function

Tranquilizer

perimetazine Preparation Products And Raw materials

Raw materials

Preparation Products

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perimetazine Suppliers

China 6 India 1 United States 2 Global 9

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55717
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Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44941
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24131
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63711
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

13093-88-4, perimetazineRelated Search:

methopromazine 2-hydroxypromazine 1-(3-AMINO-PROPYL)-PIPERIDIN-4-OL perimetazine 2-Methoxyphenothiazine Trimeprazine 3-Methoxydiphenylamine 3-Hydroxydiphenylamine

1-(3-(2-Methoxy-10H-phenothiazin-10-yl)-2-methylpropyl)piperidin-4-ol

perimetazine

AN 1317

AN-1317

Leptryl

RP 9159

RP-9159

1-[3-(2-methoxyphenothiazin-10-yl)-2-methylpropyl]piperidin-4-ol

4-Piperidinol, 1-[3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]-

13093-88-4