ChemicalBook > CAS DataBase List > Letaplimab
Letaplimab
- Product Name
- Letaplimab
- CAS No.
- 2283356-07-8
- Chemical Name
- Letaplimab
- Synonyms
- Letaplimab;Letaplimab (anti-CD47);Research Grade Letaplimab;Research Grade Letaplimab (DHG17604)
- CBNumber
- CB110617044
- Formula Weight
- 0
- MOL File
- Mol file
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Letaplimab Property
- form
- Liquid
- color
- Colorless to light yellow
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Letaplimab Chemical Properties,Usage,Production
Uses
Letaplimab (IBI-188) is a human IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis[1].
References
[1] Miao Miao, et al. A Phase 1b Study to Evaluate Safety and Efficacy of IBI188 in Combination with Azacitidine (AZA) As a First-Line Treatment in Subjects with Newly Diagnosed Higher Risk Myelodysplastic Syndrome. MYELODYSPLASTIC SYNDROMES-CLINICAL AND EPIDEMIOLOGICAL NOVEMBER 15, 2022.
Letaplimab Preparation Products And Raw materials
Raw materials
Preparation Products
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Letaplimab Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
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