2-BROMO-5-AMINO-4-PICOLINE
- Product Name
- 2-BROMO-5-AMINO-4-PICOLINE
- CAS No.
- 156118-16-0
- Chemical Name
- 2-BROMO-5-AMINO-4-PICOLINE
- Synonyms
- 6-BroMo-4-Methyl-pyridin-3-ylaMine;2-BROMO-5-AMINO-4-PICOLINE;2-BROMO-5-AMINO-4-PICOLIN...;6-Bromo-4-methyl-3-pyridinamine;2-Bromo-5-amino-4-methylpyridine;3-Amino-6-bromo-4-methylpyridine;5-Amino-2-bromo-4-methylpyridine;3-Pyridinamine, 6-bromo-4-methyl-;5-Amino-2-bromo-4-methylpyridine,98%;2-BROMO-5-AMINO-4-PICOLINE ISO 9001：2015 REACH
- CBNumber
- CB11076065
- Molecular Formula
- C6H7BrN2
- Formula Weight
- 187.04
- MOL File
- 156118-16-0.mol
2-BROMO-5-AMINO-4-PICOLINE Property
- Boiling point:
- 306.9±37.0 °C(Predicted)
- Density
- 1.593±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 2.38±0.18(Predicted)
- form
- Powder
- color
- Brown
- CAS DataBase Reference
- 156118-16-0
Safety
- RIDADR
- UN2811
- HazardClass
- 6.1
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- PHB00200
- Product name
- 2-Bromo-5-amino-4-picoline
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 1 g
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- B678075
- Product name
- 6-Bromo-4-methylpyridin-3-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B678075
- Product name
- 6-Bromo-4-methylpyridin-3-amine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA41979
- Product name
- 5-Amino-2-bromo-4-methylpyridine
- Packaging
- 5G
- Price
- $40
- Updated
- 2021/12/16
- Product number
- W3394
- Product name
- 5-Amino-2-bromo-4-methylpyridine
- Packaging
- 10g
- Price
- $65
- Updated
- 2021/12/16
2-BROMO-5-AMINO-4-PICOLINE Chemical Properties,Usage,Production
Synthesis
23056-47-5
156118-16-0
A suspension of 2-bromo-4-methyl-5-nitropyridine (XIV) (200 g, 921 mmol, 1.00 eq.) was formed with NH4Cl (240 g, 4.49 mol, 4.87 eq.) in EtOH (3.50 L) and water (150 mL). The mixture was heated to 50 °C with stirring. Subsequently, Fe (120 g, 2.15 mol, 2.33 eq.) and HCl (10.2 g, 279 mmol, 0.30 eq.) were added to the mixture. The suspension was heated to 80 °C and kept for 3 hours. After completion of the reaction, the mixture was cooled to 25 °C and filtered through a diatomaceous earth plug. The filtrate was concentrated under reduced pressure to give a residue. The residue was dissolved in EtOAc (1L x 3) and washed with brine. The organic layer was dried with sodium sulfate, filtered and concentrated under reduced pressure to give 6-bromo-4-methylpyridin-3-amine (XV) as a brown solid (167.9 g, 898 mmol, 97.4% yield), which could be used for the next reaction without further purification.1H NMR (CDCl3,400 MHz) δ ppm 2.15 (s, 3H), 3.44 (br s 2H), 7.14 (s, 1H), 7.78 (s, 1H); ESIMS m/z 186.8 ([M + H]+).
References
[1] Patent: WO2017/23975, 2017, A1. Location in patent: Paragraph 0610; 0611
[2] Patent: WO2017/24026, 2017, A1. Location in patent: Paragraph 0614; 0615
[3] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 15, p. 3441 - 3446
[4] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 22, p. 5258 - 5264
[5] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 6, p. 2441 - 2452
2-BROMO-5-AMINO-4-PICOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-BROMO-5-AMINO-4-PICOLINE manufacturers
- Product
- 2-BROMO-5-AMINO-4-PICOLINE 156118-16-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-29
- Product
- 2-BROMO-5-AMINO-4-PICOLINE 156118-16-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-04-30
- Product
- 2-BROMO-5-AMINO-4-PICOLINE 156118-16-0
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08