5-Amino-2-bromo-6-picoline

Product Name: 5-Amino-2-bromo-6-picoline
CAS No.: 126325-47-1
Chemical Name: 5-Amino-2-bromo-6-picoline
Synonyms: EOS-60356;3-Amino-6-bromo-2-methyL;6-Bromo-5-amino-2-picoline;3-AMINO-6-BROMO-2-PICOLINE;5-AMINO-2-BROMO-6-PICOLINE;6-Bromo-2-methyl-3-pyridinamine;6-broMo-2-Methyl-3-aMinopyridine;3-AMINO-6-BROMO-2-METHYLPYRIDINE;6-bromo-2-methylpyridine-3-amine;2-Bromo-5-amino-6-methylpyridine
CBNumber: CB5137022
Molecular Formula: C6H7BrN2
Formula Weight: 187.04
MOL File: 126325-47-1.mol

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5-Amino-2-bromo-6-picoline Property

Melting point:: 110-111℃
Boiling point:: 284.4±35.0 °C(Predicted)
Density: 1.593±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 2.45±0.10(Predicted)
form: Solid
color: Off-white
CAS DataBase Reference: 126325-47-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-41-37/38-22
Safety Statements: 26-36-39
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2928
Product name: 3-Amino-6-bromo-2-methylpyridine
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: A2928
Product name: 3-Amino-6-bromo-2-methylpyridine
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $132
Updated: 2025/07/31

TRC

Product number: A594935
Product name: 5-Amino-2-bromo-6-picoline
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Oakwood

Product number: 040412
Product name: 5-Amino-2-bromo-6-picoline
Purity: 98%
Packaging: 1g
Price: $10
Updated: 2021/12/16

Apolloscientific

Product number: OR40190
Product name: 3-Amino-6-bromo-2-methylpyridine
Packaging: 1g
Price: $27
Updated: 2021/12/16

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5-Amino-2-bromo-6-picoline Chemical Properties,Usage,Production

Chemical Properties

crystalline powder

Uses

5-Amino-2-bromo-6-picoline is a useful research intermediate.

Synthesis

22282-96-8

126325-47-1

General procedure for the synthesis of 2-bromo-5-amino-6-methylpyridine from 2-bromo-5-nitro-6-methylpyridine: 6-bromo-2-methyl-3-nitropyridine (XIV) (250 g, 1.15 mol, 1.00 equiv) and NH4Cl (300 g, 5.61 mol, 4.88 equiv) were suspended in a mixture of EtOH (3.50 L) and water ( 150 mL) in a solvent mixture. The suspension was heated to 65 °C under stirring. Subsequently, Fe (130 g, 2.33 mol, 2.02 eq.) and HCl (15.3 g, 419 mmol, 0.36 eq.) were added to the reaction system. The reaction mixture was heated to 80 °C and maintained at this temperature for 3 hours. After completion of the reaction, the mixture was cooled to 25 °C and filtered through a diatomaceous earth plug. The filtrate was concentrated under reduced pressure to give the crude product. The crude product was dissolved in EtOAc (1 L x 3) and washed with brine. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 6-bromo-2-methylpyridin-3-amine (XV) as a brown solid (373 g, 1.99 mol, 86.7% yield), which could be used in the next reaction without further purification.1H NMR (DMSO-d6, 400 MHz) δ ppm: 6.01 (dd, J = 2.3, 7.9 Hz, 2H). 7.9 Hz, 2H), 7.03 (d, J = 8.2 Hz, 1H); ESIMS m/z: 186.8 ([M + H]+).

References

[1] Patent: WO2017/23993, 2017, A1. Location in patent: Paragraph 0615; 0616
[2] Patent: WO2017/24004, 2017, A1. Location in patent: Paragraph 0610-0611
[3] Patent: WO2017/24025, 2017, A1. Location in patent: Paragraph 0611
[4] Patent: WO2017/24003, 2017, A1. Location in patent: Paragraph 0610; 0611
[5] Patent: US2016/347717, 2016, A1. Location in patent: Paragraph 0593; 0594

5-Amino-2-bromo-6-picoline Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Amino-2-bromo-6-picoline Suppliers

Americas 1 Canada 1 China 154 Europe 3 France 2 Germany 3 India 16 Japan 1 Switzerland 1 United Kingdom 13 United States 35 Global 230

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View Lastest Price from 5-Amino-2-bromo-6-picoline manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-Amino-2-bromo-6-picoline 126325-47-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-04

Henan Fengda Chemical Co., Ltd

Product: 5-Amino-2-bromo-6-picoline 126325-47-1
Price: US $6.00-0.20/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-03

Dideu Industries Group Limited

Product: 5-Amino-2-bromo-6-picoline 126325-47-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-25

126325-47-1, 5-Amino-2-bromo-6-picolineRelated Search:

4-Methylpyridine 3-Aminopyridine DIMETHYLAMINOPYRIDINE, POLYMER-BOUND Glycine 6-Aminocaproic acid ALTRENOGEST 2-Amino-6-methylpyridine 2,6-Lutidine 2-Aminopyridine 4-Dimethylaminopyridine 2-Bromo-6-methylpyridine Tris(hydroxymethyl)aminomethane 2-BROMOMETHYL-PYRIDINE Bromine 2-BROMO-5-NITRO-6-PICOLINE 4-Chlorophenethylamine 2-Amino-5-bromo-6-methylpyridine 3-AMINO-6-BROMO-2-PHENYLPYRIDINE

3-AMINO-6-BROMO-2-METHYLPYRIDINE

3-AMINO-6-BROMO-2-PICOLINE

6-BROMO-2-METHYL-PYRIDIN-3-YLAMINE

6-Bromo-5-amino-2-picoline

6-BROMO-3-AMINO-2-PICOLINE (5-AMINO-2-BROMO-6-PICOLINE)

5-AMINO-2-BROMO-6-PICOLINE (5-AMINO-2-BROMO-6-METHYLPYRIDINE)

3-Pyridinamine, 6-bromo-2-methyl-

2-Bromo-5-amino-6-methylpyridine

6-bromo-2-methylpyridine-3-amine

6-Bromo-2-methylpyridin-3-amine, 5-Amino-2-bromo-6-picoline

6-broMo-2-Methyl-3-aMinopyridine

5-AMINO-2-BROMO-6-METHYLPYRIDINE

5-AMINO-2-BROMO-6-PICOLINE

EOS-60356

3-Amino-6-bromo-2-methyL

5-Amino-2-bromo-6-methylpyridine,98%

5-Amino-2-bromo-6-picoline ISO 9001：2015 REACH

6-Bromo-2-methyl-3-pyridinamine

2-bromo-6-methyl-5-amino pyridine

126325-47-1

126325-47-197%

Heterocycle-Pyridine series

Amino-pyridine series

Pyridines

Boronic Acid

Pyridine