5-AMINO-3-BROMO-2-METHYLPYRIDINE

Product Name: 5-AMINO-3-BROMO-2-METHYLPYRIDINE
CAS No.: 186593-43-1
Chemical Name: 5-AMINO-3-BROMO-2-METHYLPYRIDINE
Synonyms: 5-AMINO-3-BROMO-2-PICOLINE;3-Bromo-5-Amino-2-Picoline;5-Amino-3-bromo-2-methylp...;5-Amino-3-Bromo-2-methylpyridin;5-Bromo-6-methyl-3-pyridinamine;5-Bromo-6-methylpyridin-3-amine;2-Methyl-3-broMo-5-aMinopyridine;5-AMINO-3-BROMO-2-METHYLPYRIDINE;5-aminio-3-bromo-2-methylpyridine;3-Pyridinamine, 5-bromo-6-methyl-
CBNumber: CB5841596
Molecular Formula: C6H7BrN2
Formula Weight: 187.04
MOL File: 186593-43-1.mol

More

Less

5-AMINO-3-BROMO-2-METHYLPYRIDINE Property

Melting point:: 103.0 to 108.0 °C
Boiling point:: 281.3±35.0 °C(Predicted)
Density: 1.593±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder to crystal
pka: 4.53±0.20(Predicted)
color: White to Brown
InChI: InChI=1S/C6H7BrN2/c1-4-6(7)2-5(8)3-9-4/h2-3H,8H2,1H3
InChIKey: UCLLYIVDXZGQSZ-UHFFFAOYSA-N
SMILES: C1=NC(C)=C(Br)C=C1N

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: A2996
Product name: 5-Amino-3-bromo-2-methylpyridine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $170
Updated: 2025/07/31

TCI Chemical

Product number: A2996
Product name: 5-Amino-3-bromo-2-methylpyridine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $528
Updated: 2025/07/31

TRC

Product number: A602175
Product name: 5-Amino-3-bromo-2-methylpyridine
Packaging: 500mg
Price: $85
Updated: 2021/12/16

TRC

Product number: A602175
Product name: 5-Amino-3-bromo-2-methylpyridine
Packaging: 1g
Price: $140
Updated: 2021/12/16

AK Scientific

Product number: W4033
Product name: 5-Amino-3-bromo-2-methylpyridine
Packaging: 5g
Price: $147
Updated: 2021/12/16

More

Less

5-AMINO-3-BROMO-2-METHYLPYRIDINE Chemical Properties,Usage,Production

Uses

5-?Amino-?3-?bromo-?2-?methylpyridine is a versatile reactant used in different synthetic preparations. It was used in the synthesis of amino acids by asymmetric enzymic transamination of keto acids in presence of axially chiral pyridoxamines as catalysts.

Synthesis

1190862-72-6

186593-43-1

The general procedure for the synthesis of 2-methyl-3-bromo-5-aminopyridine from 5-bromo-6-methylnicotinic acid was as follows: 5-bromo-6-methylpyridine-3-carboxylic acid (1 g, 4.63 mmol) was dissolved in a solvent mixture of tert-butanol (6.6 mL) and N,N-dimethylformamide (15 mL), followed by triethylamine (5.15 mL, 37.04 mmol) and diphenylphosphoryl azide (0.51 mL, 5.093 mmol). The reaction mixture was heated to 100°C and stirred for 2 hours. Upon completion of the reaction, the progress was monitored by thin layer chromatography (TLC). The solvent was evaporated to dryness and the residue was dissolved in saturated sodium bicarbonate solution and extracted with ethyl acetate. The organic phase was dried over anhydrous sodium sulfate and filtered and the solvent was evaporated to dryness. The residue was purified by silica gel column chromatography to give a white solid. The white solid was dissolved in dichloromethane (10 mL), a dioxane solution of 4N HCl was added and stirred for 2 hours at room temperature. Upon completion of the reaction, the solvent was evaporated to dryness to give 5-bromo-6-methylpyridin-3-ylamine (white solid, 130 mg).

References

[1] Patent: CN103420977, 2016, B. Location in patent: Paragraph 0293-0296

5-AMINO-3-BROMO-2-METHYLPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-AMINO-3-BROMO-2-METHYLPYRIDINE Suppliers

Americas 1 China 120 Europe 1 India 5 Japan 1 United Kingdom 2 United States 11 Global 141

Changzhou chennuo Biotechnology Co., Ltd

Tel: 17768395970
Email: 35015765@qq.com
Country: China
ProdList: 45
Advantage: 58

ChangShu Haitian Fine Chemicals Co.,Ltd

Tel: 13913622609
Fax: 86-512-52893680
Email: 974295387@qq.com
Country: China
ProdList: 192
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Chiba Pharmaceutical Science and technology Co, Ltd.

Tel: 0531-81313138 13066006660
Fax: QQ: 3366077777
Email: chibapharm@foxmail.com
Country: China
ProdList: 3991
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

More

Less

View Lastest Price from 5-AMINO-3-BROMO-2-METHYLPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 5-AMINO-3-BROMO-2-METHYLPYRIDINE 186593-43-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-30

Career Henan Chemical Co

Product: 5-AMINO-3-BROMO-2-METHYLPYRIDINE 186593-43-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200KG
Release date: 2018-12-23

186593-43-1, 5-AMINO-3-BROMO-2-METHYLPYRIDINERelated Search:

2-AMINO-5-BROMO-3-METHYLPYRIDINE 4-Bromo-2-methyl-3-pyridinamine 5-AMINO-2-BROMO-3-METHYLPYRIDINE 2-AMINO-5-BROMO-4-METHYLPYRIDINE 5-AMINO-3-BROMO-2-METHYLPYRIDINE 2-AMINO-3-BROMO-5-METHYLPYRIDINE 6-AMINO-3-BROMO-2-METHYLPYRIDINE,2-AMINO-5-BROMO-6-METHYLPYRIDINE 5-AMINO-2-BROMO-6-METHYLPYRIDINE,3-AMINO-6-BROMO-2-METHYLPYRIDINE 2-AMINO-3-BROMO-4-METHYLPYRIDINE 4-AMINO-5-BROMO-3-METHYLPYRIDINE 3-Amino-2-bromo-4-methylpyridine 4-AMINO-5-BROMO-2-METHYLPYRIDINE 2-AMINO-3-BROMO-6-METHYLPYRIDINE 3-Bromo-2-methylpyridine 5-BROMO-2-HYDROXY-3-NITRO-6-PICOLINE 2-Chloro-3-Nitro-5-Bromo-6-Picoline 3-AMINO-5-BROMO-6-METHYLPYRIDIN-2-OL 2-Amino-3-nitro-4,6-dimethyl-5-bromopyridine

5-AMINO-3-BROMO-2-METHYLPYRIDINE

3-Bromo-5-Amino-2-Picoline

5-Bromo-6-methylpyridin-3-amine

2-Methyl-3-broMo-5-aMinopyridine

5-Amino-3-bromo-2-methylp...

5-Bromo-6-methyl-3-pyridinamine

3-PyridinaMine, 5-broMo-2-chloro-6-Methyl-

5-BroMo-6-Methyl-pyridin-3-ylaMine

5-AMINO-3-BROMO-2-PICOLINE

5-aminio-3-bromo-2-methylpyridine

5-Amino-3-Bromo-2-methylpyridin

3-Pyridinamine, 5-bromo-6-methyl-

5-AMINO-3-BROMO-2-METHYLPYRIDINE ISO 9001：2015 REACH

186593-43-1

Heterocycle-Pyridine series

Amines

Pyridines