2-AMINO-3-BROMO-4-METHYLPYRIDINE
- Product Name
- 2-AMINO-3-BROMO-4-METHYLPYRIDINE
- CAS No.
- 40073-38-9
- Chemical Name
- 2-AMINO-3-BROMO-4-METHYLPYRIDINE
- Synonyms
- 3-broMo-4-Methylpyridin-2-aMine;2-AMINO-3-BROMO-4-PICOLINE;3-Bromo-4-methyl-2-pyridinamine;2-AMino-3-broMo-4-Methyopyridine;2-AMINO-3-BROMO-4-METHYLPYRIDINE;3-Bromo-4-methylpyridin-2-ylamine;2-Pyridinamine, 3-bromo-4-methyl-;2 - amino 4 - methy 3 - bromo pyridine;2-AMINO-3-BROMO-4-METHYLPYRIDINE ISO 9001:2015 REACH
- CBNumber
- CB2697736
- Molecular Formula
- C6H7BrN2
- Formula Weight
- 187.04
- MOL File
- 40073-38-9.mol
2-AMINO-3-BROMO-4-METHYLPYRIDINE Property
- Boiling point:
- 255.2±35.0 °C(Predicted)
- Density
- 1.593±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 4.71±0.47(Predicted)
- Appearance
- Off-white to light yellow Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A595808
- Product name
- 2-Amino-3-bromo-4-picoline
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- J97881
- Product name
- 2-Amino-3-bromo-4-picoline
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA42913
- Product name
- 2-Amino-3-bromo-4-picoline
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FA42913
- Product name
- 2-Amino-3-bromo-4-picoline
- Packaging
- 500mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- FA42913
- Product name
- 2-Amino-3-bromo-4-picoline
- Packaging
- 1g
- Price
- $138
- Updated
- 2021/12/16
2-AMINO-3-BROMO-4-METHYLPYRIDINE Chemical Properties,Usage,Production
Synthesis
3430-29-3
40073-38-9
General procedure for the synthesis of 2-amino-3-bromo-4-methylpyridine from 2-amino-3,5-dibromo-4-methylpyridine: 3,5-dibromo-4-methylpyridin-2-amine (3.38 g, 12.7 mmol) was dissolved in dry tetrahydrofuran (60 mL) under the protection of nitrogen, and cooled to -78°C. n-Butyllithium (1.9 M in pentane, 13.4 mL, 25.4 mmol) was added slowly and the reaction mixture turned orange. The reaction was quenched by careful addition of water (10 mL) after 1 h of continuous stirring at -78°C. The reaction was stopped by the addition of a solution of 10 N sodium hydroxide. The pH of the reaction mixture was adjusted to about 12 with 10 N sodium hydroxide solution and then extracted with dichloromethane (3 x 30 mL). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give an orange oil. Purification by silica gel column chromatography (with ether as eluent) afforded 2-amino-3-bromo-4-methylpyridine (1.68 g, 71% yield) as a light yellow solid.1H NMR (CDCl3) δ 2.32 (s, 3H), 5.00 (br s, 2H), 6.52 (d, 1H, J = 6.0 Hz), 7.84 (d, 1H, J = 6.0 Hz ).
References
[1] Patent: US2005/277668, 2005, A1. Location in patent: Page/Page column 28
[2] Patent: EP3372601, 2018, A1. Location in patent: Paragraph 0693; 0694
2-AMINO-3-BROMO-4-METHYLPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-3-BROMO-4-METHYLPYRIDINE manufacturers
- Product
- 2-AMINO-3-BROMO-4-METHYLPYRIDINE 40073-38-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-27
- Product
- 2-AMINO-3-BROMO-4-METHYLPYRIDINE 40073-38-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10 tons
- Release date
- 2020-01-10