2-Amino-3,5-dibromo-4-methylpyridine

Product Name: 2-Amino-3,5-dibromo-4-methylpyridine
CAS No.: 3430-29-3
Chemical Name: 2-Amino-3,5-dibromo-4-methylpyridine
Synonyms: 3,5-Dibromo-4-methylpyridin-2-amine;2-Amino-3,5-dibromo-4-methyL;2-Amino-3,5-Dibromo-4-pioline;2-AMINO-3,5-DIBROMO-4-PICOLINE;3,5-DIBROMO-4-METHYL-2-PYRIDINAMINE;2-AMINO-3,5-DIBROMO-4-METHYLPRIDINE;2-AMINO-3,5-DIBROMO-4-METHYPYRIDINE;2-AMINO-3,5 DIBROMO-4-METHYL PYRIDINE;2-Pyridinamine, 3,5-dibromo-4-methyl-;3,5-DibroMo-4-Methyl-pyridin-2-ylaMine
CBNumber: CB1361584
Molecular Formula: C6H6Br2N2
Formula Weight: 265.93
MOL File: 3430-29-3.mol

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2-Amino-3,5-dibromo-4-methylpyridine Property

Melting point:: 123-124 °C
Boiling point:: 276.5±35.0 °C(Predicted)
Density: 1.990±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: solid
pka: 2.52±0.50(Predicted)
color: Off white
InChI: InChI=1S/C6H6Br2N2/c1-3-4(7)2-10-6(9)5(3)8/h2H,1H3,(H2,9,10)
InChIKey: LLGXZSVWYCKUBB-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Br)C(C)=C1Br
CAS DataBase Reference: 3430-29-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

H351Suspected of causing cancer

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A576678
Product name: 2-Amino-3,5-dibromo-4-methylpyridine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 026738
Product name: 2-Amino-3,5-dibromo-4-methylpyridine
Purity: 98%
Packaging: 25g
Price: $50
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-9-Y8
Product name: 2-Amino-3,5-dibromo-4-methylpyridine
Packaging: 25g
Price: $58
Updated: 2021/12/16

Matrix Scientific

Product number: 026738
Product name: 2-Amino-3,5-dibromo-4-methylpyridine
Purity: 98%
Packaging: 5g
Price: $14
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-9-Y8
Product name: 2-Amino-3,5-dibromo-4-methylpyridine
Packaging: 5G
Price: $16
Updated: 2021/12/16

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2-Amino-3,5-dibromo-4-methylpyridine Chemical Properties,Usage,Production

Synthesis

695-34-1

3430-29-3

a) Preparation of 2-amino-3,5-dibromo-4-methylpyridine: 2-amino-4-methylpyridine (30.0 g, 0.277 mol) was dissolved in 72% sulfuric acid (130 mL) and cooled to 0°C in an ice bath. Bromine (21.5 mL, 0.416 mol) was added slowly dropwise with stirring, and the rate of dropwise acceleration was controlled to keep the reaction temperature at 0 °C. After the dropwise addition, the reaction mixture was gradually warmed to 25 °C and the reaction was stirred at this temperature for 18 hours. Upon completion of the reaction, the reaction solution was slowly poured into ice water and the pH was adjusted with 50% sodium hydroxide solution to 10. At this point, the target product 2-amino-3,5-dibromo-4-methylpyridine precipitated as a solid, which was collected by filtration. The filtrate was extracted with dichloromethane, the organic layers were combined and dried over anhydrous magnesium sulfate. The dried organic phase was concentrated and the resulting solid was combined with the solid obtained by previous filtration and further purified by fast column chromatography (eluent: 2% methanol/dichloromethane) to give the final white solid product 2-amino-3,5-dibromo-4-methylpyridine (42.7 g, 58% yield). The structure of the product was confirmed by 1H NMR (CDCl3): δ 8.08 (s, 1H), 4.95 (bs, 2H), 2.51 (s, 3H).

References

[1] Patent: US6440993, 2002, B1
[2] Patent: US2005/277668, 2005, A1. Location in patent: Page/Page column 27-28
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 24, p. 10056 - 10070

2-Amino-3,5-dibromo-4-methylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-3,5-dibromo-4-methylpyridine Suppliers

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View Lastest Price from 2-Amino-3,5-dibromo-4-methylpyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Amino-3,5-dibromo-4-methylpyridine 3430-29-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-30

Henan Fengda Chemical Co., Ltd

Product: 2-Amino-3,5-dibromo-4-methylpyridine 3430-29-3
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

Dideu Industries Group Limited

Product: 2-Amino-3,5-dibromo-4-methylpyridine 3430-29-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-25

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3,5-Dibromo-4-methylpyridin-2-amine

2-AMINO-3,5-DIBROMO-4-METHYLPRIDINE

2-AMINO-3,5 DIBROMO-4-METHYL PYRIDINE

2-AMINO-3,5-DIBROMO-4-PICOLINE

3,5-DIBROMO-4-METHYL-2-PYRIDINAMINE

3,5-Dibromo-4-methylpyridin-2-amine, 2-Amino-3,5-dibromo-4-picoline

3,5-DibroMo-4-Methyl-pyridin-2-ylaMine

2-Amino-3,5-dibromo-4-methyL

2-Pyridinamine, 3,5-dibromo-4-methyl-

2-Amino-3,5-dibromo-4-methylpyridine ISO 9001：2015 REACH

2-Amino-3,5-Dibromo-4-pioline

2-AMINO-3,5-DIBROMO-4-METHYPYRIDINE

3430-29-3

C6H6N2Br2

Thiophenes ,Thiazolines/Thiazolidines

Pyridines

Pyridine