5-BROMO-2-METHYLPYRIDIN-3-AMINE

Description Reference

Product Name: 5-BROMO-2-METHYLPYRIDIN-3-AMINE
CAS No.: 914358-73-9
Chemical Name: 5-BROMO-2-METHYLPYRIDIN-3-AMINE
Synonyms: 3-Amino-5-bromopicoline;3-Amino-5-bromo-2-methylp...;3-Amin-5-bromo-2-methylpyridine;5-bromo-2-methyl-3-Pyridinamine;5-BROMO-2-METHYLPYRIDIN-3-AMINE;2-Methyl-3-amino-5-bromopyridine;3-Amino-5-bromo-2-methylpyridine;5-Bromo-2-Methylpyridine-3-amine;3-pyridinaMine, 5-broMo-2-Methyl;5-BroMo-2-Methyl-pyridin-3-ylaMine
CBNumber: CB6818821
Molecular Formula: C6H7BrN2
Formula Weight: 187.04
MOL File: 914358-73-9.mol

More

Less

5-BROMO-2-METHYLPYRIDIN-3-AMINE Property

Melting point:: 108-109℃
Boiling point:: 283.5±35.0 °C(Predicted)
Density: 1.593±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: crystalline solid
pka: 4.53±0.20(Predicted)
color: Off-white
InChI: InChI=1S/C6H7BrN2/c1-4-6(8)2-5(7)3-9-4/h2-3H,8H2,1H3
InChIKey: CBAXYISWNGGXOZ-UHFFFAOYSA-N
SMILES: C1(C)=NC=C(Br)C=C1N

More

Less

Safety

Risk Statements: 41
Safety Statements: 26-39
HazardClass: IRRITANT
HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

SynQuest Laboratories

Product number: 3H30-9-42
Product name: 3-Amino-5-bromo-2-methylpyridine
Packaging: 1g
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 066625
Product name: 3-Amino-5-bromo-2-methylpyridine
Purity: 97%
Packaging: 5g
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: J94603
Product name: 5-Bromo-2-methylpyridin-3-amine
Packaging: 5g
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA55674
Product name: 3-Amino-5-bromo-2-methylpyridine
Packaging: 500mg
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-9-42
Product name: 3-Amino-5-bromo-2-methylpyridine
Packaging: 5G
Price: $75
Updated: 2021/12/16

More

Less

5-BROMO-2-METHYLPYRIDIN-3-AMINE Chemical Properties,Usage,Production

Description

5-Bromo-2-methylpyridin-3-amine is also named as 3-Amino-5-bromo-2-methylpyridine. It can be converted to 5-bromo-2-methyl-3-pyridinol by diazotization with sodium nitrite in aqueous sulfuric acid. 5-Bromo-2-methyl-3-pyridinol can be used to make brominated dihydropyridines, which are substrates for the palladium catalyzed coupling, a process to produce compounds for the treatment of patients with disorders, such as central nervous system disorders.

Reference

G. Dull, J. Munoz, J. Genus, J. Moore, Hydroxybenzoate salts of metanicotine compounds, Patent US20060122239A1

Uses

3-Amino-5-bromo-2-methylpyridine (3ABMP) is a kind of biochemical reagent.

Synthesis

911434-05-4

914358-73-9

The general procedure for the synthesis of 2-methyl-3-amino-5-bromopyridine from 5-bromo-2-methyl-3-nitropyridine was as follows: 5-bromo-2-methyl-3-nitropyridine (13.8 g, 63.9 mmol) was dissolved in industrial methanol (330 mL) at 40 °C, followed by the addition of powdered iron (20 g) in batches to avoid agglomeration. Next, concentrated aqueous hydrochloric acid (5 mL) was added for elution. The resulting dark brown mixture was stirred vigorously under reflux conditions for 2 h. After completion of the reaction, it was cooled to room temperature and filtered through Celite (the filter cake was washed with 1 L of industrial methanol). The filtrate was concentrated under reduced pressure to remove the solvent, and the residue was dissolved in ethyl acetate (200 mL), the organic phase was washed with saturated aqueous sodium bicarbonate (200 mL), and dried with anhydrous magnesium sulfate. Finally, the solvent was removed under reduced pressure to afford the target product 5-bromo-2-methylpyridin-3-amine as an orange solid (10.7 g, 90% yield). The structure of the product was confirmed by 1HNMR (400 MHz, CDCl3, δ): 7.91 (s, 1H), 7.00 (s, 1H), 3.75 (br.s, 2H), 2.25 (s, 3H).

References

[1] Bergmeyer, et al. "Biochemical reagents." Methods of Enzymatic Analysis. Academic Press, 1965. 967-1037.

5-BROMO-2-METHYLPYRIDIN-3-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-BROMO-2-METHYLPYRIDIN-3-AMINE Suppliers

China 211 India 5 United Kingdom 3 United States 13 Global 232

Changzhou chennuo Biotechnology Co., Ltd

Tel: 17768395970
Email: 35015765@qq.com
Country: China
ProdList: 45
Advantage: 58

Fuxin Custchem Fine Chemical Co., Ltd.

Tel: 0418-5113999 18740177324
Fax: 2851606178
Email: sales@custchem.com.cn
Country: China
ProdList: 441
Advantage: 58

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 993
Advantage: 62

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
Advantage: 55

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

ChangShu Haitian Fine Chemicals Co.,Ltd

Tel: 13913622609
Fax: 86-512-52893680
Email: 974295387@qq.com
Country: China
ProdList: 192
Advantage: 61

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

More

Less

View Lastest Price from 5-BROMO-2-METHYLPYRIDIN-3-AMINE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-BROMO-2-METHYLPYRIDIN-3-AMINE 914358-73-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-29

Henan Fengda Chemical Co., Ltd

Product: 5-BROMO-2-METHYLPYRIDIN-3-AMINE 914358-73-9
Price: US $6.00-0.20/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-03

Shaanxi Dideu Medichem Co. Ltd

Product: 5-bromo-2-methylpyridin-3-amine 914358-73-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2019-12-25

914358-73-9, 5-BROMO-2-METHYLPYRIDIN-3-AMINERelated Search:

5-AMINO-3-BROMO-2-METHOXYPYRIDINE 3-AMINO-5-BROMO-PYRIDIN-2-OL 3-AMINO-5-BROMO-2-METHOXYPYRIDINE 2-Bromo-6-methylpyridin-3-amine 6-Bromo-N-methylpyridin-2-amine 5-BROMO-6-METHYLPYRIDIN-2-AMINE 3-BROMO-5-METHYLPYRIDIN-2-AMINE 5-BROMO-3-METHYLPYRIDIN-2-AMINE,5-Bromo-3-methylpyridin-2-amine ,98% 5-Bromo-6-methylpyridin-3-amine 5-Bromo-2-methylpyridine 3-BROMO-6-METHYLPYRIDIN-2-AMINE 3-Bromo-5-methylpyridin-4-amine 2-BROMO-4-METHYLPYRIDIN-3-AMINE 5-Bromo-2-methylpyridin-4-amine 5-BROMO-N-METHYLPYRIDIN-2-AMINE 4-BROMO-6-METHYLPYRIDIN-2-AMINE 4-Amino-3-bromo-5-methylpyridine 6-BROMO-2-METHYLPYRIDIN-3-AMINE

5-BROMO-2-METHYLPYRIDIN-3-AMINE

5-bromo-2-methyl-3-Pyridinamine

3-Amino-5-bromo-2-methylpyridine

3-Amino-5-bromo-2-methylp...

5-BroMo-2-Methyl-pyridin-3-ylaMine

3-pyridinaMine, 5-broMo-2-Methyl

3-Amino-5-bromopicoline

5-Bromo-2-Methylpyridine-3-amine

3-Amin-5-bromo-2-methylpyridine

5-BROMO-2-METHYLPYRIDIN-3-AMINE ISO 9001：2015 REACH

2-Methyl-3-amino-5-bromopyridine

914358-73-9