2-Pyrimidinecarbonitrile, 5-chloro- (9CI)
- Product Name
- 2-Pyrimidinecarbonitrile, 5-chloro- (9CI)
- CAS No.
- 38275-56-8
- Chemical Name
- 2-Pyrimidinecarbonitrile, 5-chloro- (9CI)
- Synonyms
- 2-Cyano-5-chloropyrimidine;5-chloropyriMidine-2-carbonitril;5-chloropyrimidine-2-carbonitrile;5-Chloro-2-pyrimidinecarbonitrile;2-Pyrimidinecarbonitrile, 5-chloro-;5-Chloropyrimidine-2-carbonitrile, 98%;2-Pyrimidinecarbonitrile, 5-chloro- (9CI);5-CHLOROPYRIMIDINE-2-CARBONITRILE,PURITY:97% MIN(HPLC);tert-butyl 3-oxospiro[benzofuran-2,4-piperidine]-1-carboxylate
- CBNumber
- CB11081407
- Molecular Formula
- C5H2ClN3
- Formula Weight
- 139.54
- MOL File
- 38275-56-8.mol
2-Pyrimidinecarbonitrile, 5-chloro- (9CI) Property
- Melting point:
- 78℃
- Boiling point:
- 292℃
- Density
- 1.43
- Flash point:
- 130℃
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -4.65±0.22(Predicted)
- Appearance
- White to yellow Powder
- InChI
- InChI=1S/C5H2ClN3/c6-4-2-8-5(1-7)9-3-4/h2-3H
- InChIKey
- XCZYVEHAGNDPGY-UHFFFAOYSA-N
- SMILES
- C1(C#N)=NC=C(Cl)C=N1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C428475
- Product name
- 5-Chloropyrimidine-2-carbonitrile
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 073912
- Product name
- 5-Chloropyrimidine-2-carbonitrile
- Purity
- 95+%
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
- Product number
- FC142774
- Product name
- 5-Chloropyrimidine-2-carbonitrile
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FC142774
- Product name
- 5-Chloropyrimidine-2-carbonitrile
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FC142774
- Product name
- 5-Chloropyrimidine-2-carbonitrile
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
2-Pyrimidinecarbonitrile, 5-chloro- (9CI) Chemical Properties,Usage,Production
Synthesis
143-33-9
38275-47-7
38275-56-8
The general procedure for the synthesis of 2-cyano-5-chloropyrimidine from sodium cyanide and 2-methylsulfonyl-5-chloropyrimidine was as follows: a solution of 5-chloro-2-(methylsulfonyl)pyrimidine (3.5 g, 18.1 mmol) in dimethylsulfoxide (10 mL) was batch-treated with sodium cyanide (0.9 g, 18.4 mmol) at 10 °C for 10 min. The reaction mixture was continued to be stirred for 10 minutes before being diluted with cold water (30 mL) and filtered. The resulting solid was washed with cold water (3 x 30 mL) and dried to give 2-cyano-5-chloropyrimidine (2.05 g, 81% yield) as a light yellow solid.ESI-MS: 139 (MH+).
References
[1] Patent: US2007/270438, 2007, A1. Location in patent: Page/Page column 34
[2] Synthetic Communications, 2002, vol. 32, # 1, p. 153 - 157
2-Pyrimidinecarbonitrile, 5-chloro- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
2-Pyrimidinecarbonitrile, 5-chloro- (9CI) Suppliers
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View Lastest Price from 2-Pyrimidinecarbonitrile, 5-chloro- (9CI) manufacturers
- Product
- 5-Chloropyrimidine-2-carbonitrile 38275-56-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2020-05-15
- Product
- 2-Pyrimidinecarbonitrile, 5-chloro- (9CI) 38275-56-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 97-99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-19