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ChemicalBook > CAS DataBase List > 2-(Di-tert-butylphosphino)biphenyl

2-(Di-tert-butylphosphino)biphenyl

Reactions
Product Name
2-(Di-tert-butylphosphino)biphenyl
CAS No.
224311-51-7
Chemical Name
2-(Di-tert-butylphosphino)biphenyl
Synonyms
JohnPhos;ditert-butyl-(2-phenylphenyl)phosphane;2-(DI-T-BUTYLPHOSPHINO)BIPHENYL;(2-biphenyl)di-tert-butylphosphine;JnhnPhos;98% JohnPhos;JohnPhos 97%;2-(Di-t-butyL;phosphino)biphenyL;Pyridaben Impurity 2
CBNumber
CB1108350
Molecular Formula
C20H27P
Formula Weight
298.4
MOL File
224311-51-7.mol
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2-(Di-tert-butylphosphino)biphenyl Property

Melting point:
86-88 °C (lit.)
Boiling point:
405.5±24.0 °C(Predicted)
Density 
1 g/cm3
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly, Heated, Sonicated)
form 
Crystals or Crystalline Powder
color 
White
Water Solubility 
Insoluble
BRN 
8322131
Stability:
Air Sensitive
InChI
InChI=1S/C20H27P/c1-19(2,3)21(20(4,5)6)18-15-11-10-14-17(18)16-12-8-7-9-13-16/h7-15H,1-6H3
InChIKey
CNXMDTWQWLGCPE-UHFFFAOYSA-N
SMILES
P(C1=CC=CC=C1C1=CC=CC=C1)(C(C)(C)C)C(C)(C)C
CAS DataBase Reference
224311-51-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-22
Safety Statements 
36/37/39-26-22
WGK Germany 
3
F 
10-23
TSCA 
No
HazardClass 
AIR SENSITIVE
HS Code 
29029090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
638439
Product name
JohnPhos
Purity
97%
Packaging
1g
Price
$61.3
Updated
2024/03/01
Sigma-Aldrich
Product number
638439
Product name
JohnPhos
Purity
97%
Packaging
5g
Price
$291
Updated
2024/03/01
TCI Chemical
Product number
D3387
Product name
2-(Di-tert-butylphosphino)biphenyl
Purity
>98.0%(GC)
Packaging
1g
Price
$73
Updated
2024/03/01
TCI Chemical
Product number
D3387
Product name
2-(Di-tert-butylphosphino)biphenyl
Purity
>98.0%(GC)
Packaging
5g
Price
$301
Updated
2024/03/01
Strem Chemicals
Product number
15-1045
Product name
2-(Di-t-butylphosphino))-1,1'-biphenyl, 99% JohnPhos
Packaging
500mg
Price
$29
Updated
2024/03/01
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2-(Di-tert-butylphosphino)biphenyl Chemical Properties,Usage,Production

Reactions

  1. Ligand used in the palladium-catalyzed synthesis of aromatic amines from aryl chlorides, bromides and triflates.
  2. Ligand employed in a very active and general catalyst for Suzuki coupling reactions using aryl chlorides, bromides and triflates.
  3. Ligand used in palladium-catalyzed synthesis of oxindoles from α-chloroacetanilides.
  4. Effective ligand used in palladium-catalyzed arylation of thiazoles.
  5. Used in the formation of 2-benzylindolines via sequential palladium-catalyzed N-arylation/cyclization/C-arylation.
  6. Selective in the palladium-catalyzed arylation of silyl enol ethers formed from copper-catalyzed reduction of enones.

Chemical Properties

white to light yellow crystal powde

Uses

suzuki reaction

Uses

2-(Di-tert-butylphosphino)biphenyl (also known as JohnPhos) is a Buchwald ligand that is highly efficient in palladium-catalyzed reactions.

General Description

JohnPhos is a Buchwald′s sterically bulky biaryl phosphine ligand. It is a reactive dialkylbiaryl phosphine ligand which catalyzes the carbon-nitrogen bond-forming reactions. Coordination chemistry of gold catalysts bearing JohnPhos as ligand has been investigated by NMR spectroscopy.

2-(Di-tert-butylphosphino)biphenyl Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(Di-tert-butylphosphino)biphenyl Suppliers

Americas 1 Belgium 1 Canada 1 China 288 Europe 1 Germany 8 India 7 Japan 8 Norway 1 Russia 1 South Korea 1 Switzerland 2 Ukraine 1 United Kingdom 9 United States 33 Global 363
Xinxiang Runyu Material Co., Ltd.
Tel
166-166-37336996 15690792173
Fax
0373-7759608
Email
chenxi.song@runvmat.com
Country
China
ProdList
299
Advantage
55
Henan Research New Material Co., Ltd.
Tel
1890-3931531 18903931628
Email
sales036@researchvip.com
Country
China
ProdList
182
Advantage
58
Puyang Huicheng Electronic Material Co. Ltd.
Tel
0393-0393-0393-8910800 15039333257
Fax
0393-8912775
Email
info@huichengchem.com
Country
China
ProdList
557
Advantage
64
BeiJing Greenchem Technology Co.,Ltd.
Tel
131-21959385 15640741633
Fax
010-62925455
Email
chemrocking@bjgreenchem.com
Country
China
ProdList
269
Advantage
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing Donghualituo Techonlogy Development Co.,Ltd.
Tel
010-88425576
Fax
(+86)-10-88425546
Email
sales@dhltchem.com
Country
China
ProdList
793
Advantage
59
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from 2-(Di-tert-butylphosphino)biphenyl manufacturers

XINXIANG RUNYU MATERIAL CO., LTD.
Product
2-(Di-t-butylphosphino)biphenyl 224311-51-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
0.98
Supply Ability
500kg
Release date
2021-12-02
Hebei Weibang Biotechnology Co., Ltd
Product
2-(Di-tert-butylphosphino)biphenyl 224311-51-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-10
Henan Research New Materials Co., Ltd.
Product
2-(Di-tert-butylphosphino)biphenyl 224311-51-7
Price
US $0.00/g
Min. Order
1g
Purity
99%；sales036@researchvip.com;18903931628;
Supply Ability
100KG
Release date
2024-11-23

224311-51-7, 2-(Di-tert-butylphosphino)biphenylRelated Search:

tert-Butanol Tri-tert-butylphosphine Biphenyl Tributylphosphine Di-tert-butyl peroxide Butylated Hydroxytoluene T-BUTYLPHOSPHINE Di-tert-butylphosphine TERT-BUTYLPHOSPHONIC ACID 2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL 2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL (2-BIPHENYL)DI-TERT-BUTYLPHOSPHINE GOLD& RAC-2-(DI-T-BUTYLPHOSPHINO)-1,1'-BINAPHTHYL 2-DI-TERT-BUTYLPHOSPHINO-2',4',6'-TRIISOPROPYLBIPHENYL 2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAM& 2-(Di-tert-butylphosphino)biphenyl 2-(2'-DI-TERT-BUTYLPHOSPHINE)BIPHENYLPALLADIUM(II) ACETATE 2,2'-BIS(DI-TERT-BUTYLPHOSPHINO)BIPHENYL

  • (2-biphenyl)di-tert-butylphosphine
  • (2-BIPHENYLYL)DI-TERT-BUTYLPHOSPHINE
  • 2-(DI-TERT-BUTYLPHOSPHINO)BIPHENYL
  • 2-(DI-T-BUTYLPHOSPHINO)BIPHENYL
  • BIPHENYL-2-YL-DI-TERT-BUTYL-PHOSPHANE
  • 2-(Di-t-butylphosphino)biphenyl,99%JohnPhos
  • 2-(Di-t-butylphosphine) biphenyl
  • PHOSPHINE, [1,1''-BIPHENYL]-2-YLBIS(1,1-DIMETHYLETHYL)-
  • JohnPhos
  • 2-(Di-tert-butylphosphino)-biphenyl, JohnPhos
  • (2-Biphenylyl)di-tert-butylphosphine, 2-(Di-tert-butylphosphino)biphenyl, JohnPhos
  • 2-(Di-tert-butylphosphino)biphenyl,99%
  • (2-Biphenyl)di-tert-butylphosphine,(2-Biphenylyl)di-tert-butylphosphine, 2-(Di-tert-butylphosphino)biphenyl, JohnPhos
  • 2-[Bis(tert-butyl)phosphino]biphenyl 98%
  • 2-(Di-t-butylphosphino)-1,1'- biphenyl (Johnphos)
  • 2-[Bis(tert-butyl)phosphino]biphenyl
  • 98% JohnPhos
  • (2-Biphenylyl)di-tert-butylphosphine JohnPhos
  • 2-(Di-tert-butylphosphino)biphenyl, 99% 500MG
  • 2-(Di-tert-butylphosphiNA)biphenyl
  • 2-(Di-t-butylphosphino)biphenyl, JohnPhos
  • [1,1'-biphenyl]-2-yldi-tert-butylphosphine
  • 2-(Di-t-butylphosphino)biphenyl,98% JohnPhos
  • 2-(Di-tert-butylphosphino)biph
  • 2-(Di-tert-butylphosphino)biphenyl (2-Biphenyl)di-tert-butylphosphine
  • JnhnPhos
  • JohnPhos 97%
  • 99% SynonyMs (2-Biphenyl)di-tert-butylphosphine
  • ditert-butyl-(2-phenylphenyl)phosphane
  • 2-(Di-t-butylphosphino))-1,1'-biphenyl
  • 2-(Di-t-butylphosphino))-1,1'-biphenyl, 99% JohnPhos
  • [1,1'-biphenyl]-2-yldi-tert-bu
  • 2-(Di-t-butylphosphino)
  • 2-(Di-tert-butylphosphino)biphenyl&gt
  • 2-(Di-t-butyL
  • phosphino)biphenyL
  • 2-(Di-tert-butylphosphino)-1,1'-biphenyl
  • 1,1'-Biphenyl]-2-ylbis(1,1-dimethylethyl)phosphine
  • itert-butyl-(2-phenylphenyl)phosphane
  • 2-(Di-t-butylphosphino))-1,1'-biphenyl
  • [1,1'-Biphenyl]-2-ylbis(1,1-dimethylethyl)phosphine
  • 2- (di tert butyl phosphine) biphenyl
  • 1,1'-biphenyl]-2-yldi-tert-butylphosphine
  • Pyridaben Impurity 2
  • 224311-51-7
  • C20H27P
  • C6H5C6H4PCCH332
  • Buchwald Ligands
  • Catalysis and Inorganic Chemistry
  • Phosphorus Compounds
  • Achiral Phosphine
  • Aryl Phosphine
  • Buchwald Ligands Series
  • Buchwald Ligands&Precatalysts
  • organophosphine ligand
  • Ligand
  • Benzene derivatives
  • Phosphines