2-METHOXY-6-METHYLANILINE
- Product Name
- 2-METHOXY-6-METHYLANILINE
- CAS No.
- 50868-73-0
- Chemical Name
- 2-METHOXY-6-METHYLANILINE
- Synonyms
- 6-METHYL-O-ANISIDINE;6-Methoxy-o-toluidine;2-Amino-3-methylanisole;2-METHOXY-6-METHYLANILINE;6-Methoxy-2-methylaniline;2-Methyl-6-methoxyaniline;2-Methoxy-6-methylaniline>2-Methoxy-6-methylbenzenamine;2-Methoxy-6-methylaniline 98%;2-Methoxy-6-methyl-phenylamine
- CBNumber
- CB1116915
- Molecular Formula
- C8H11NO
- Formula Weight
- 137.18
- MOL File
- 50868-73-0.mol
2-METHOXY-6-METHYLANILINE Property
- Melting point:
- 26-29 °C (lit.)
- Boiling point:
- 62 °C/0.15 mmHg (lit.)
- Density
- 1.0630 (rough estimate)
- refractive index
- 1.5647 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), Methanol (Sparingly)
- pka
- 4.39±0.10(Predicted)
- form
- Solid
- color
- Clear Brown Oil to Pale Red to Dark Red
- InChI
- InChI=1S/C8H11NO/c1-6-4-3-5-7(10-2)8(6)9/h3-5H,9H2,1-2H3
- InChIKey
- HKOJYPPTIPJZAZ-UHFFFAOYSA-N
- SMILES
- C1(N)=C(C)C=CC=C1OC
- CAS DataBase Reference
- 50868-73-0
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-37/39
- WGK Germany
- 3
- HS Code
- 2922290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 360090
- Product name
- 2-Methoxy-6-methylaniline
- Purity
- 98%
- Packaging
- 5g
- Price
- $85
- Updated
- 2023/01/07
- Product number
- 360090
- Product name
- 2-Methoxy-6-methylaniline
- Purity
- 98%
- Packaging
- 25g
- Price
- $127
- Updated
- 2023/01/07
- Product number
- M1804
- Product name
- 2-Methoxy-6-methylaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $100
- Updated
- 2025/07/31
- Product number
- M1804
- Product name
- 2-Methoxy-6-methylaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $401
- Updated
- 2025/07/31
- Product number
- M329148
- Product name
- 2-Methoxy-6-methylaniline
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
2-METHOXY-6-METHYLANILINE Chemical Properties,Usage,Production
Uses
2-Methoxy-6-methylaniline may be used in the synthesis of 7-methoxy-1H-indazole, an inhibitor of nitric oxide synthase.
Synthesis
5345-42-6
50868-73-0
General procedure for the synthesis of 2-methoxy-6-methylaniline from 3-methyl-2-nitroanisole: Step A2; a) Preparation of intermediate 3: 1-methoxy-3-methyl-2-nitrobenzene (25 g, 149.7 mmol) was dissolved in ethanol (100 ml). 10% palladium/carbon catalyst (2.5 g) was added and the reaction mixture was subjected to hydrogenation at room temperature for 24 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration. The filtrate was concentrated under reduced pressure to give Intermediate 3 in a yield of 20.02 g (97% yield). The structure of intermediate 3 was confirmed by CI-MS with a molecular ion peak of 138 ([M + H]+).
References
[1] New Journal of Chemistry, 2006, vol. 30, # 2, p. 168 - 176
[2] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 6, p. 3309 - 3320
[3] Organic letters, 2000, vol. 2, # 3, p. 277 - 280
[4] Patent: WO2006/15985, 2006, A1. Location in patent: Page/Page column 54-55
[5] Journal of the Chemical Society, 1926, p. 1425
2-METHOXY-6-METHYLANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-METHOXY-6-METHYLANILINE manufacturers
- Product
- 2-METHOXY-6-METHYLANILINE 50868-73-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-10
- Product
- 2-METHOXY-6-METHYLANILINE 50868-73-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-08