3-Bromo-5-chlorophenol

Uses

Product Name: 3-Bromo-5-chlorophenol
CAS No.: 56962-04-0
Chemical Name: 3-Bromo-5-chlorophenol
Synonyms: 3-BroMo-chlorophenol;3-BROMO-5-CHLOROPHENOL;Phenol, 3-bromo-5-chloro-;3-BroMo-5-chlorophenol, 97+%
CBNumber: CB11177445
Molecular Formula: C6H4BrClO
Formula Weight: 207.45
MOL File: 56962-04-0.mol

More

Less

3-Bromo-5-chlorophenol Property

Melting point:: 66-70℃
Boiling point:: 256°C (rough estimate)
Density: 1.6027 (rough estimate)
vapor pressure: 0.004-0.084Pa at 20-50℃
refractive index: 1.5730 (estimate)
storage temp.: Inert atmosphere,2-8°C
pka: 8.04±0.10(Predicted)
form: Solid
Appearance: White to off-white Solid
LogP: 3.2 at 25℃ and pH2
Surface tension: 54.7mN/m at 1g/L and 20℃
CAS DataBase Reference: 56962-04-0

More

Less

Safety

HS Code: 2908190090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B684153
Product name: 3-Bromo-5-chlorophenol
Packaging: 1g
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB66909
Product name: 3-Bromo-5-chlorophenol
Packaging: 2g
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: W7052
Product name: 3-Bromo-5-chlorophenol
Packaging: 1g
Price: $63
Updated: 2021/12/16

Oakwood

Product number: 077970
Product name: 3-Bromo-5-chlorophenol
Purity: 97%
Packaging: 5g
Price: $27
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0029809
Product name: 3-BROMO-5-CHLOROPHENOL
Purity: 95.00%
Packaging: 1G
Price: $653.73
Updated: 2021/12/16

More

Less

3-Bromo-5-chlorophenol Chemical Properties,Usage,Production

Uses

3-Chloro-5-bromophenol is an important pharmaceutical intermediate that can be used in the preparation of a variety of pharmaceutical products.

Synthesis

108-37-2

56962-04-0

General procedure for the synthesis of 3-bromo-5-chlorophenol from m-chlorobromobenzene: In an argon-purged flask, (1,5-cyclooctadiene)(methoxy)iridium(I) dimer (84 mg, 0.13 mmol), 4,4'-di-tert-butyl-2,2'-bipyridine (69 mg, 0.26 mmol), and bis(pinacolate)diboron (1.29 g, 5.11 mmol) were added. 5.11 mmol), followed by hexane (26 mL) and 1-bromo-3-chlorobenzene (1 mL, 8.51 mmol) sequentially. The reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the mixture was concentrated under vacuum and redissolved in acetone (26 mL) followed by addition of an aqueous (26 mL) solution of Oxone (5.23 g, 8.51 mmol) [Note: exothermic phenomena were observed during the reaction].After 10 min, the reaction mixture was diluted with dichloromethane. The organic and aqueous layers were separated and the aqueous layer was extracted with dichloromethane. The organic phases were combined, washed with brine, dried and concentrated in vacuum to give 3-bromo-5-chlorophenol (1.43 g, 81% yield).LCMS (Method 3): retention time 3.74 min, mass-to-charge ratio m/z 205,207 [M-H+].

References

[1] Patent: US2014/364412, 2014, A1. Location in patent: Paragraph 0683; 0684
[2] Patent: WO2014/195402, 2014, A1. Location in patent: Page/Page column 217
[3] Patent: WO2009/115515, 2009, A1. Location in patent: Page/Page column 44-45
[4] Journal of the American Chemical Society, 2003, vol. 125, # 26, p. 7792 - 7793
[5] Synthesis, 2011, # 6, p. 857 - 859

3-Bromo-5-chlorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Bromo-5-chlorophenol Suppliers

China 145 India 2 United Kingdom 3 United States 9 Global 159

Accela ChemBio Inc.

Tel: +1(858) 699-3322
Fax: +1(858) 876-1948
Email: marketing@accelachem.com
Country: United States
ProdList: 6024
Advantage: 65

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

BoroPharm Inc.

Tel: --
Fax: --
Email: sales@boropharm.com
Country: United States
ProdList: 96
Advantage: 50

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

More

Less

View Lastest Price from 3-Bromo-5-chlorophenol manufacturers

Career Henan Chemical Co

Product: 3-Bromo-5-chlorophenol 56962-04-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-05-23

56962-04-0, 3-Bromo-5-chlorophenolRelated Search:

TETRACHLOROGUAJACOL 2-BROMO-5-CHLOROPHENOL 4-BROMO-3-CHLOROPHENOL 4-Bromo-2-chlorophenol 5-Bromo-2-chlorophenol Bromochlorophenol Blue BROMOCHLOROPHEN 2-Bromo-4-chlorophenol 2,6-DIBROMO-4-CHLOROPHENOL 3-Bromo-2-chlorophenol 4-bromo-6-chlorobenzo[d]oxazol-2(3H)-one 1-BROMO-3-CHLORO-5-METHOXYBENZENE 3-Bromo-5-chlorophenol 2-Chloro-4-bromo-6-trifluoromethoxyaniline

3-BroMo-chlorophenol

3-BroMo-5-chlorophenol, 97+%

Phenol, 3-bromo-5-chloro-

3-BROMO-5-CHLOROPHENOL

56962-04-0

56926-04-0

Bromine Compounds

Chlorine Compounds

Phenols