1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one

Product Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one
CAS No.: 5627-05-4
Chemical Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one
Synonyms: dihydrouridine;6-Dihydrouridine;Uridine, 5,6-dihydro-;Uridine Impurity 28（5,6-Dihydrouridine）;5,6-Dihydrouridine RNA-modified nucleoside D;1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one;1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)dihydropyrimidine-2,4(1H,3H)-dione
CBNumber: CB11235574
Molecular Formula: C9H14N2O6
Formula Weight: 246.22
MOL File: 5627-05-4.mol

More

Less

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one Property

Density: 1.614±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 16 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
form: A crystalline solid
pka: 12.40±0.20(Predicted)
Stability:: Hygroscopic

More

Less

Safety

HS Code: 2934999090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: D449668
Product name: 5,6-Dihydrouridine
Packaging: 100mg
Price: $800
Updated: 2021/12/16

TRC

Product number: D449668
Product name: 5,6-Dihydrouridine
Packaging: 250mg
Price: $1755
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H12-1-03
Product name: 5,6-Dihydrouridine
Purity: 95%
Packaging: 250mg
Price: $55
Updated: 2021/12/16

ChemScene

Product number: CS-0059431
Product name: 5,6-Dihydrouridine
Purity: 99.87%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUC0001384
Product name: 5,6-DIHYDRO-URIDINE
Purity: 95.00%
Packaging: 5MG
Price: $501.22
Updated: 2021/12/16

More

Less

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one Chemical Properties,Usage,Production

Uses

5,6-Dihydrouridine is an intermediate used in the synthesis of 3,4,5,6-Tetrahydrouridine (>80%) (T310250), which is a derivative of Uridine (U829910). Tetrahydrouridine (THU) is a potent inhibitor of cytidine. It inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels deaminase (CDA), and thus can be used as a potential and promising treatment for tumors with highly expressed CDA.

Definition

ChEBI: The uridine derivative obtained by formal hydrogenation of the endocyclic double bond in the uracil ring.

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one Suppliers

China 25 Germany 1 India 2 United Kingdom 1 United States 7 Global 36

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-021-64543801 13764082696
Email: 2355241799@qq.com
Country: China
ProdList: 42982
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18739
Advantage: 57

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9900
Advantage: 58

Zhengzhou GranLen pharmaceutical Technology Co., Ltd.

Tel: 0371-85513397
Email: info@granlen.com
Country: China
ProdList: 497
Advantage: 55

Beijing Qinling Mountains Pharmaceutical Co., Ltd.

Tel: 010-61241352 18901327973
Email: sales@qlmed.com
Country: China
ProdList: 518
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
Email: cb6@aikonchem.com
Country: China
ProdList: 16687
Advantage: 50

Lanzhou Angeli Biochemical Technology Co., Ltd.

Tel: 0931-8235634 13321316780
Fax: +86(931) 4873122
Email: 1455540579@qq.com
Country: China
ProdList: 959
Advantage: 55

Zhengzhou Granlen Sciences, ltd.

Tel: 0371-85513397
Email: info@granlen.com
Country: China
ProdList: 1842
Advantage: 58

BOC Sciences

Tel: +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19743
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

5627-05-4, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneRelated Search:

dihydrouridine

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one

Uridine, 5,6-dihydro-

Uridine Impurity 28（5,6-Dihydrouridine）

6-Dihydrouridine

5,6-Dihydrouridine RNA-modified nucleoside D

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)dihydropyrimidine-2,4(1H,3H)-dione

5627-05-4