3-Bromo-1,2-diaminobenzene
- Product Name
- 3-Bromo-1,2-diaminobenzene
- CAS No.
- 1575-36-6
- Chemical Name
- 3-Bromo-1,2-diaminobenzene
- Synonyms
- 3-Bromobenzene-1,2-diamine;2-diaminobenzene;3-broMobenzene-1;2-AMino-3-broMoaniline;3-Bromo-2-amino-aniline;1,2-Diamino-3-bromobenzene;3-BroMo-o-phenylenediaMine;1,2-BenzenediaMine,3-broMo-;3-Bromophenylene-1,2-diamine;(2-amino-3-bromophenyl)amine
- CBNumber
- CB11262693
- Molecular Formula
- C6H7BrN2
- Formula Weight
- 187.04
- MOL File
- 1575-36-6.mol
3-Bromo-1,2-diaminobenzene Property
- Melting point:
- 125-126 °C
- Boiling point:
- 127-128 °C
- Density
- 1.697±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- form
- solid
- pka
- 3.09±0.10(Predicted)
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B680220
- Product name
- 3-Bromobenzene-1,2-diamine
- Packaging
- 10g
- Price
- $1320
- Updated
- 2021/12/16
- Product number
- 075355
- Product name
- 3-Bromobenzene-1,2-diamine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $108
- Updated
- 2021/12/16
- Product number
- W3419
- Product name
- 3-Bromo-1,2-diaminobenzene
- Packaging
- 1g
- Price
- $111
- Updated
- 2021/12/16
- Product number
- OR11721
- Product name
- 3-Bromobenzene-1,2-diamine
- Purity
- 98%
- Packaging
- 250mg
- Price
- $41
- Updated
- 2021/12/16
- Product number
- FB144040
- Product name
- 3-Bromobenzene-1,2-diamine
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
3-Bromo-1,2-diaminobenzene Chemical Properties,Usage,Production
Uses
3-Bromo-1,2-diaminobenzene is used in the preparation of isomeric bromo analogues of Benzo-1H-triazole as potential inhibitors of protein kinases.
Synthesis
22034-13-5
1575-36-6
General procedure for the synthesis of 3-bromo-1,2-diaminobenzene from 4-bromo-2,1,3-benzothiadiazole: 4-bromo-benzo[c][1,2,5]thiadiazole (10 g, 46.5 mmol) and NaBH4 (17.6 g, 465 mmol) were added to a 2000 mL single-necked flask followed by 900 mL of ethanol (EtOH). The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the solvent was removed using a rotary evaporator. Subsequently, the reaction mixture was extracted with chloroform (CHCl3). The organic layer was washed with saturated brine solution and then the organic layer was dried with anhydrous magnesium sulfate (MgSO4). Finally, the solvent was removed by rotary evaporator to afford 3-bromo-1,2-diaminobenzene (8.0 g, 47.6 mmol, 92% yield).
References
[1] Patent: KR101612903, 2016, B1. Location in patent: Paragraph 0110-0112
[2] Journal of Physical Chemistry B, 2012, vol. 116, # 24, p. 7259 - 7268
[3] Patent: WO2009/111260, 2009, A1. Location in patent: Page/Page column 31-32
[4] Patent: WO2009/108838, 2009, A1. Location in patent: Page/Page column 95-96
[5] Chemical Communications, 2013, vol. 49, # 39, p. 4304 - 4306
3-Bromo-1,2-diaminobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Bromo-1,2-diaminobenzene manufacturers
- Product
- 3-Bromo-1,2-diaminobenzene 1575-36-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-07
- Product
- 3-Bromo-1,2-diaminobenzene 1575-36-6
- Price
- US $101.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-29
- Product
- 3-Bromo-1,2-diaminobenzene 1575-36-6
- Price
- US $100.00/bag
- Min. Order
- 1bag
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-09-14